?
Нарушение оценки значимости информации при шизофрении
The history of study of schizophrenia has more than 100 years. During all this period there was collected
a lot of data on clinical picture of the disease, psychological peculiarities of patients, biochemical and
electrophysiological phenomena. In this respect it becomes actual nowadays to look for a concept that
could combine different levels of schizophrenia research (clinical, biochemical, social, etc.) and explain
relationships with various symptoms of the disease. In this article we analyze experimental psychological
data on thinking of patients, instrumental studies (ERP, fMRI, rhythmic patterns of thinking, dopamine
theory) and their relationship with clinical implications. It is shown that all these data complement each
other and allow us to tell about a basic violation in schizophrenia – the difficulty of patients to differentiate
between more and less salient information. We can observe the violation on different levels of
schizophrenia investigation and explain different symptoms of the disease as manifestations of that basic
violation.