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Учителя большого города. Сергей Бердоносов.
Большой город. 2013.
Леенсон Е. И.
Priority areas:
engineering science
Language:
Russian
Gureev M., Advanced Science 2026 P. 1–13
Targeted protein degradation represents a promising therapeutic strategy, yet its broader application is often limited by the scarcity of usable E3 ligases. Glutathione peroxidase 4 (GPX4) is a key target for inducing ferroptosis, but achieving sustained and potent inhibition remains challenging with conventional enzymatic inhibitors. Herein, we report the first small‐molecule GPX4 degraders that incorporate ...
Added: September 26, 2026
Рупова Р. М., Вопросы теологии 2023 Т. 5 № 3
В рецензии рассматривается новый издательский проект, посвященный концептуальным основам христианской теологии образования. Предложенная в нем парадигма образования, в названии которой на первом месте стоит слово «теология», свидетельствует о том, что образованию придается богословски значимый статус, оно строится в перспективе базовых ценностей человеческого бытия, связанных с богочеловеческими отношениями. Лишь в силу выстраивания этой вертикали образование может ...
Added: September 25, 2026
Diachkova E., Nikulin D., Кубкин Я. В. et al., American Journal of Respiratory and Critical Care Medicine 2026 Vol. 212
Accurate classification of a patient with pulmonary hypertension (PH) into one of five groups is fundamental for appropriate disease management strategies. The time from disease onset to correct diagnosis is unacceptably long in many cases. Chronic thromboembolic pulmonary hypertension (CTEPH) develops as a consequence of venous thromboemboli, resulting in a more pronounced hereditary predisposition to ...
Added: September 23, 2026
Xu Y., Ryabov F., Alexandrov I. et al., USA 2026 Vol. 6 No. 8 Article 101324
Центромеры обеспечивают расхождение хромосом, однако организацию их хроматина в пределах повторяющейся альфа-сателлитной ДНК долгое время было трудно изучать. Для решения этой задачи мы создали гаплотип-разрешённые аннотации сателлитной ДНК для полной диплоидной сборки генома человека T2T-HG002. Затем с помощью метода направленного метилирования с секвенированием длинных прочтений (DiMeLo-seq) мы картировали центромерный белок A (CENP-A), модификацию H3K9me3 и ...
Added: September 23, 2026
Hebbar P., Ryabov F., Alexandrov I. et al., Cell 2026 Vol. 189 P. 4891–4908.e12
The common marmoset is a New World monkey widely used to study primate evolution and human disease. We present a telomere-to-telomere (T2T) reference assembly for the species, plus three near-T2T haplotypes. These resolve previously inaccessible regions, including the centromeres, sex chromosomes, subterminal satellites, acrocentric chromosomes, and the major histocompatibility complex (MHC). We find marmoset centromeres ...
Added: September 23, 2026
М.: Факультет журналистики МГУ им. М.В.Ломоносова, 2025.
В сборнике представлены материалы II Всероссийской научно-практической конференции медиапедагогов, проведенной 3-4 октября 2025 года факультетом журналистики МГУ имени М. В. Ломоносова. Авторы описывают актуальные медиаобразовательные практики, предлагают новейшие разработки в области медиаобразования, размышляют о различных аспектах обеспечения информационно-когнитивной безопасности детей, подростков и молодежи в условиях укрепления системы духовно-нравственных ценностей российского общества. ...
Added: September 22, 2026
Karachurina L. B., Mkrtchyan N. V., Региональные исследования 2026 Т. 91 № 1 С. 34–47
Migration for higher education is one of the largest and most intense migration flows in most developed countries, and Russia is no exception. The direction of educational migration flows is determined by many factors. Among these, traditionally significant determinants of the basic gravity model include the population size of the centers participating in migration exchange ...
Added: September 19, 2026
Agadzhanyan A., Отечественная и зарубежная педагогика 2026 Т. 1 № 4 (117) С. 96–110
In the context of the implementation of the Federal State Educational Standard and the challenges of the digital environment, which weaken the influence of traditional institutions of socialization, purposeful education and achievement of personal results of students becomes a priority task of the school. A class with a unique educational potential can be considered as ...
Added: September 18, 2026
Ravedovskaya U., Didenko A., Journal of Teaching English for Specific and Academic Purposes 2025 Vol. 13 No. 3 P. 529–538
Emergence of generative artificial intelligence (GenAI) is revolutionizing teaching and evaluation in higher education. Early adopters have already demonstrated how large language model (LLM) conversational agents can serve as on-demand tutors, yet empirical evidence regarding their effectiveness in facilitating conceptual learning in non-computational domains is scant. Based on constructivist learning theory, this paper presents a ...
Added: September 18, 2026
Шиповалова Л. В., Социология власти 2026 Vol. 38 No. 1 P. 224–243
This article examines the integration of large language model based chatbots into educational practices in Russian higher education through the lens of critical theory and curriculum ideologies. Drawing on Ivan Illich’s concept of convivial tools and Jürgen Habermas’s distinction between instrumental and communicative rationality, the authors conceptualize large language models as technologies capable of operating ...
Added: September 18, 2026
Shaitan A., Ke Y., Shutao C. et al., 2026 No. 24 Article 181
Background Therapeutic peptides exert pivotal effects in diverse biological processes, and have attracted significant interest in the field of biomedicine in recent years. However, most existing methods often fail to adequately capture the intricate interactions among amino acid residues and the contextual dependencies within peptide sequences, which hampers the extraction of deep semantic representations and ...
Added: September 18, 2026
Anton Rogachev, Sysoeva O., Frontiers in Systems Neuroscience 2025 Vol. 19 Article 1658243
Added: September 17, 2026
Rogachev A.O., Sysoeva O. V., Cognitive Systems Research 2024 Vol. 86 Article 101236
Receptive speech is the ability to understand speech addressed to a person. It is a crucial process for a child’s cognitive development. We examine the relationship between receptive speech and neural tracking of natural speech in 52 children aged 3–8 years to infer the neurophysiological mechanisms underlying speech development. We registered a 32-channel electroencephalogram (EEG) ...
Added: September 17, 2026
Blinova E., Sherbakova O., Learning and Instruction 2026 Vol. 106 Article 102432
Abstract
Background
Knowledge abstractness is one of the factors affecting learning outcomes, particularly in learning from multimedia texts. However, most previous studies on multimedia learning have focused on manipulating pictorial abstractness, while the role of text topic abstractness remains largely unexplored.
Aims
1. Examine how topic abstractness influences multimedia learning outcomes when pictorial abstractness remains constant. 2. Investigate how ...
Added: September 16, 2026
Poddiakov A., / Series Social Science Research Network "Social Science Research Network". 2026. No. 7437658.
Clarity of knowledge and reasoning is necessary in many cases. Yet vagueness in scientific thinking related to surprise, curiosity, "ability to engage with not-knowing" (de Freitas) and abductive reasoning is also a crucially important source of scientific creativity which supplements combinatorial logic when dealing with the already known. Starting from studies by C. S. Peirce ...
Added: September 15, 2026
Gaete Sepulveda M. A., Dymarskaya O. Y., Sosa Gómez G., Mexico: Centros Culturales de México, 2026.
Universities are called to respond to social fragility, the environmental crisis, technological transformation, artificial
intelligence, and the loss of trust in institutions. This book argues that higher education cannot be limited to teaching,
research, or technology transfer. Its deepest purpose is to contribute to the holistic human development of individuals,
communities, and territories.
By articulating the third mission, service-learning, and the Fifth ...
Added: September 15, 2026
Гулов А. П., Касаткин П. И., Bakulev A., Вестник Томского государственного университета 2026 № 524 С. 165–176
The article examines how digitalization transforms the scale, structure, and typology of the All-Russian School Olympiad by conceptualizing it as an integrated digital environment and a cultural-educational institution. The study aims to use official Olympiad statistical reports for 2023–2025 and an analysis of the Olympiad’s digital infra-structure to describe types of Olympiad cultures at regional ...
Added: September 14, 2026
Chertenkov K., Вопросы статистики 2026 Т. 33 № 4 С. 80–89
В статье рассматривается дифференциация итоговой рождаемости в зависимости от уровня образования женщин. Используются данные Всероссийских переписей населения 2010 и 2020 гг., а также Всесоюзной переписи населения 1989 г. Применяются методы когортного анализа, включающие расчет среднего числа рожденных детей, доли бездетных и доли матерей, родивших трех и более детей, для реальных женских поколений 1930–1981 годов рождения. ...
Added: September 12, 2026
JOURNAL OF INTERDISCIPLINARY STUDIES IN EDUCATION 2026 Vol. 15 No. 7
Soyut
Bu makale, Rusça eğitim veren yükseköğretim kurumlarında öğrenim gören Türk öğrencilerin akademik yeterliliklerinin tanınması ve yanlış tanınmasını nasıl deneyimlediklerini incelemektedir. 15 görüşmenin ikincil nitel analizine dayanarak, dilsel performansın sınıf içi katılım ve sözlü değerlendirmede güvenilirlik yargılarını nasıl şekillendirdiğini açıklamak için dilsel olarak aracılık edilen tanıklık adaletsizliği kavramını geliştirmektedir. Üçbiriyle ilişkili dinamik ortaya çıkmıştır: değerlendirmede epistemik ...
Added: September 11, 2026
Tikhomirova A., Chowdhury M. A., Мир России: Социология, этнология 2026 Vol. 35 No. 4 P. 98–117
Cooperation between Russia and China in the field of education has expanded significantly.
In 2026, the number of Russian students studying in China reached 21,000. However, empirical
evidence shows that students face many difficulties adapting to the new environment. Given
the growing popularity of Chinese universities among Russian students, the present study
aimed to identify the factors and mechanisms ...
Added: September 11, 2026
Novikov A., Polyhedron 2026 Vol. 299 Article 118358
Two new supramolecular halometalate hybrid complexes, (H2bpen){[MCl5](I2)} (M = Sb(III) (1) and Bi(III) (2); bpen – 1,2-Bis(4-pyridyl)ethylene, have been prepared. Despite very close similarity of the nature of cations, they reveal significant structural difference from the (H2bpe){[MCl5](I2)} (bpe – 1,2-bis(4-pyridil)ethane) reported earlier. We discuss these features, along with thermal stability, optical properties as well as Raman spectra ...
Added: September 2, 2026
Obijiofor O., Alexander S. Novikov, New Journal of Chemistry 2026 Vol. 50 No. 33 P. 13931–13957
The rational design of coinage metal nanocarriers requires a mechanistic understanding of metal-drug binding and predictive descriptors that translate molecular interactions into design rules. Using DFT (B3LYP-D3BJ/def2-TZVP, SMD water), we systematically investigated the binding of 5-fluorouracil (5-FU) and levodopa (l-DOPA) to neutral and cationic homo- and heteronuclear dimers of Au, Ag, and Cu (Au2, Ag2, ...
Added: August 12, 2026
Stognieva O., Новикова В. П., М.: Флинта, 2026.
Инновационный курс английского языка для специальных целей для студентов педагогических вузов предлагает погружение в актуальный образовательный дискурс: от вопросов воспитания и когнитивного развития детей и подростков до переосмысления роли школы в цифровую эпоху. Содержательной основой курса выступают аутентичные мультимодальные материалы, позволяющие анализировать глобальные тренды современных образовательных систем и подходов. Издание идеально подходит вузам, стремящимся подготовить ...
Added: July 16, 2026
Obijiofor O., Novikov A., New Journal of Chemistry 2026 Vol. 50 No. 23 P. 9749–9768
Rational design of gold-based nanocarriers for neurotherapeutics requires atomic-scale understanding of drug-material interactions. Density functional theory calculations were performed to investigate levodopa (L-DOPA) adsorption on small gold clusters (Au2–Au4) with cationic, neutral, and anionic charges, with additional validation on a larger Au10 cluster using multiple low-energy isomers. Binding free energies (ΔGbind), charge transfer, and electronic descriptors ...
Added: June 3, 2026