?
Экспрессия гена INK4A в клетках рака мочевого пузыря, ассоциированного с вирусом папиллом человека 16-го типа
БЮЛЛЕТЕНЬ ЭКСПЕРИМЕНТАЛЬНОЙ БИОЛОГИИ И МЕДИЦИНЫ, Россия. 2010. Т. 149. № 2. С. 204-208.
Волгарева Г. М., Завалишина Л. Э., Головина Д. А., Андреева Ю. Ю., Ермилова В. Д., Трофимова О. Б., Куевда Д. А., Шипулина О. Ю., Глазунова В.А., Чен Ш., Павлова Л. С., Чебан Н. Л., Матвеев В. Б., Франк Г. А.
Language:
Russian
Волгарева Г. М., Завалишина Л. Э., Трофимова О. Б. et al., Архив патологии 2010 Т. 72 № 4 С. 24-27
Проведено комплексное обследование больной рецидивирующим раком мочевого пузыря. Ранее в первичной опухоли, удаленной у нее в 2004 г., выявлена ДНК вируса папилломы человека (ВПЧ) 16-го типа, мРНК, соответствующая онкогену Е7 ВПЧ16, а также белок Е7 ВПЧ16. Больная является курильщицей, более 20 лет она проработала на химическом производстве. При рецидиве в 2009 г. ДНК ВПЧ типов ...
Added: July 14, 2015
Shtyrov Y., Smith M., Horner A. et al., Neuropsychologia 2012 Vol. 50 No. 11 P. 2605-2616
Previous research indicates that, under explicit instructions to listen to spoken stimuli or in speech-oriented behavioural tasks, the brain's responses to senseless pseudowords are larger than those to meaningful words; the reverse is true in non-attended conditions. These differential responses could be used as a tool to trace linguistic processes in the brain and their ...
Added: October 23, 2014
Vlassov V., Neuro-epidemiology 2015 Vol. 45 No. 3 P. 190-202
Background: Recent evidence suggests that stroke is increasing as a cause of morbidity and mortality in younger adults, where it carries particular significance for working individuals. Accurate and up-to-date estimates of stroke burden are important for planning stroke prevention and management in younger adults. Objectives: This study aims to estimate prevalence, mortality and disability-adjusted life ...
Added: October 29, 2015
Калинина Е. В., Березов Т. Т., Чернов Н. Н. et al., ВОПРОСЫ БИОЛОГИЧЕСКОЙ, МЕДИЦИНСКОЙ И ФАРМАЦЕВТИЧЕСКОЙ ХИМИИ, Россия 2012 Т. 10 № 5 С. 51-57
Проведена оценка экспрессии генов изоформ тиоредоксина и тиоредоксинредуктазы при формировании лекарственной устойчивости опухолевых клеток к доксорубицину. Показано, что у резистентных к DOX опухолевых клеток K562/DOX, MCF-7/DOX, SKVLB обнаружен рост экспрессии генов TRX2 и TRXRD1, тогда как повышение экспрессии гена TRX1 установлено только в клетках SKVLB. Во всех трех типах резистентных клеток обнаружен рост активности как ...
Added: July 14, 2015
Kobayashi Y., Kulikova Sofya P, Shibato J. et al., World Journal of Biological Chemistry 2015 Vol. 6 No. 4 P. 389-408
N-Methyl-D-aspartate receptors (NMDAr) are involved in multiple physiological functions and neuropsychiatric disorders. Dizocilpine (commonly referred to as MK-801) is a well-known non-competitive NMDAr antagonist with psychotomimetic properties. A combination of electrophysiological and molecular analyses reveals not only the synchrony of baseline oscillations by MK-801, but also more importantly new insight into differential gene expressions in ...
Added: October 22, 2015
Стара Загора : Издателски консорциум "КОТА", 2016
Юбилейна научна конференция за преподаватели, студенти и специалисти по здравни гриди с международно участие "10 години специалност "Медицинский лаборант" в Медицнски-колеж - Стара Загора" ...
Added: April 15, 2017
Bondarenko O. R., Ульф Л., Консультативная психология и психотерапия 2010 № 4 С. 175-190
In various comparisons between Individual Psychology and Humanistic Psychology similarities in the concept of man are seen. Furthermore the connections in the life history between Adler, the founder of Individual Psychology, and Maslow and Rogers, the two most important persons in Humanistic Psychology are shown here; Adler even was their teacher in New York in ...
Added: November 6, 2012
Сургут : Сургутский государственный университет, Копи-Центр, 2004
Главная цель Конгресса – поддержка регионообразующих процессов в зоне мирового Севера, создание единой информационной базы, отражающей современный опыт развития северных территорий, развитие межрегионального и международного сотрудничества.
Основные направления работы Конгресса: Северные регионы в системах геополитического и геоэкономического баланса Модели управления северными территориями: стратегии социального партнерства Современное предпринимательство в условиях Мирового Севера: экономические и социокультурные аспекты Гуманитарные ресурсы Севера - ...
Added: August 19, 2014
Yumaguzin V., Vinnik M. V., Вестник Башкирского университета 2015 Т. 20 № 3 С. 896-902
The article presents an analysis of the demographic losses from the main causes of death in Russia, in the Republic of Bashkortostan and in OECD countries. Based on analysis of the numbers of deaths and potential years of life lost (PYLL), there was shown the position of external factors in the structure of total mortality ...
Added: November 1, 2015
Moseley R., Shtyrov Yury, Mohr B. et al., Neuroimage 2015 Vol. 104 P. 413-422
Autism spectrum conditions (ASC) are characterised by deficits in understanding and expressing emotions and are frequently accompanied by alexithymia, a difficulty in understanding and expressing emotion words. Words are differentially represented in the brain according to their semantic category and these difficulties in ASC predict reduced activation to emotion-related words in limbic structures crucial for ...
Added: October 23, 2014
Lavrenov S. N., Luzikov Y. N., Bykov E. E. et al., Bioorganic and Medicinal Chemistry 2010 Vol. 18 No. 18 P. 6905-6913
Novel derivatives of tris(indol-3-yl)methane and tris(indol-3-yl)methylium salts with the alkyl substituents at the N-atoms of the indole rings were synthesized. An easy substitution of indole rings in trisindolylmethanes for other indoles under the action of acids is demonstrated, and the mechanism of substitution is discussed. To obtain trisindolylmethylium salts, the environmentally safe method of oxidation ...
Added: July 14, 2015
Vlassov V., Neuro-epidemiology 2015 Vol. 45 No. 3 P. 177-189
Background: There is increasing recognition of stroke as an important contributor to childhood morbidity and mortality. Current estimates of global childhood stroke burden and its temporal trends are sparse. Accurate and up-to-date estimates of childhood stroke burden are important for planning research and the resulting evidence-based strategies for stroke prevention and management. Objectives: To estimate ...
Added: October 29, 2015
Nicol R., Chapman S., Vertes P. et al., Journal of Neurophysiology (США) 2012 Vol. 107 No. 5 P. 1421-1430
How do human brain networks react to dynamic changes in the sensory environment? We measured rapid changes in brain network organization in response to brief, discrete, salient auditory stimuli. We estimated network topology and distance parameters in the immediate central response period, <1 s following auditory presentation of standard tones interspersed with occasional deviant tones ...
Added: October 23, 2014
Буторина А., Shestakova A., Николаева А. et al., Современная зарубежная психология 2012 Т. 1 С. 103-113
На сегодняшний день в клинической практике и научных исследованиях остро стоит проблема локализации речевых зон человека. Несмотря на то, что два важнейших центра речи человека были выявлены достаточно давно (зоны Брока и Вернике, отвечающая за порождение и понимание речи соответсвенно), их расположение и даже полушарная латерализация могут сильно варьировать, создавая необходимость в надежной методике картирования ...
Added: October 23, 2014
Holland R., Brindley L., Shtyrov Y. et al., Neuropsychologia 2012 Vol. 50 No. 14 P. 3713-3720
especially impaired on regular past-tense forms like played, whether the task requires production, comprehension or even the judgement that "play" and "played" sound different. Within a dual-mechanism account of inflectional morphology, these deficits reflect disruption to the rule-based process that adds (or strips) the suffix -ed to regular verb stems; but the fact that the ...
Added: October 23, 2014
Shchekotikhin A. E., Glazunova V.A., Dezhenkova L. G. et al., Bioorganic and Medicinal Chemistry 2009 Vol. 17 No. 5 P. 1861-1869
We developed the synthesis of a series of thiophene-fused tetracyclic analogues of the antitumor drug ametantrone. The reactions included nucleophilic substitution of methoxy groups in 4,11-dimethoxyanthra[2,3-b]thiophene-5,10-diones with ethylenediamines, producing the derivatives of 4,11-diaminoanthra[2,3-b]thiophene-5,10-dione in good yields. Several compounds showed marked antiproliferative potency against doxorubicin-selected, P-glycoprotein-expressing tumor cells and p53-/- cells. The cytotoxicity of some novel compounds ...
Added: July 14, 2015
Vlassov V., The Lancet 2016 Vol. 388 No. 10053 P. 1545-1602
Background
Non-fatal outcomes of disease and injury increasingly detract from the ability of the world's population to live in full health, a trend largely attributable to an epidemiological transition in many countries from causes affecting children, to non-communicable diseases (NCDs) more common in adults. For the Global Burden of Diseases, Injuries, and Risk Factors Study 2015 ...
Added: October 13, 2016
Vlassov V., The Lancet 2016 Vol. 388 No. 10053 P. 1725-1774
Background
Established in 2000, Millennium Development Goal 4 (MDG4) catalysed extraordinary political, financial, and social commitments to reduce under-5 mortality by two-thirds between 1990 and 2015. At the country level, the pace of progress in improving child survival has varied markedly, highlighting a crucial need to further examine potential drivers of accelerated or slowed decreases in ...
Added: October 13, 2016
Vlassov V.V., The Lancet 2016 Vol. 388 No. 10049 P. 1081-1088
Background
With recent improvements in vaccines and treatments against viral hepatitis, an improved understanding of the burden of viral hepatitis is needed to inform global intervention strategies. We used data from the Global Burden of Disease (GBD) Study to estimate morbidity and mortality for acute viral hepatitis, and for cirrhosis and liver cancer caused by viral ...
Added: July 9, 2016
Vlassov V., The Lancet 2014 Vol. 348 No. 9947 P. 1005-1070
Abstract: Background
The Millennium Declaration in 2000 brought special global attention to HIV, tuberculosis and malaria through the formulation of Millennium Development Goal 6 (MDG 6). The Global Burden of Disease 2013 study provides a consistent and comprehensive approach to disease estimation 1990 to 2013, and an opportunity to assess if there has been accelerated progress since the Millennium ...
Added: May 30, 2014
Moseley R., Pulvermuller F., Mohr B. et al., Journal of Autism & Developmental Disorders 2014 Vol. 44 No. 1 P. 137-153
Reading utilises at least two neural pathways. The temporal lexical route visually maps whole words to their lexical entries, whilst the nonlexical route decodes words phonologically via parietal cortex. Readers typically employ the lexical route for familiar words, but poor comprehension plus precocity at mechanically 'sounding out' words suggests that differences might exist in autism. ...
Added: October 23, 2014
Dmitrieva E., Talibov A. K., Фадейкин М. А., Ученые записки университета им. П.Ф. Лесгафта 2015 № № 3(121) С. 142-146
http://lesgaft-notes.spb.ru ...
Added: February 12, 2016
Thiel S., Bitzer S., Nierhaus T. et al., Plos One 2014 Vol. 2 No. 9 P. e89802
Perceptual decisions not only depend on the incoming information from sensory systems but constitute a combination of current sensory evidence and internally accumulated information from past encounters. Although recent evidence emphasizes the fundamental role of prior knowledge for perceptual decision making, only few studies have quantified the relevance of such priors on perceptual decisions and ...
Added: October 23, 2014