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Эффективность ибупрофена в терапии боли у детей: систематический обзор результатов рандомизированных контролируемых исследований
Вопросы современной педиатрии. 2010. Т. 9. № 6. С. 52–62.
Saygitov R.
The article presents results of systematic review of data on prophylactic and therapeutic efficacy of ibuprofen. Data search was performed by PubMed database and Google search. 27 publications for analysis were available. Prophylactic efficacy of ibuprofen was studied in 14 studies. Summarizing of the results showed that ibuprofen prevents pain and decreases its following intensity after different surgical or dental operations. There is no significant difference in prophylactic efficacy of single dose ibuprofen and acetaminophen.Therapeutic efficacy of ibuprofen was described in 13 studies. Administration of the drug for pain stopping in children is reasonable. The analgesic effect of ibuprofen compared to placebo was shown in all studies of patients with migraine and diseases of ENT-organs. 5 studies performed in last 5 years showed efficacy of ibuprofen in trauma patients, including children with non-complicated fractures of extremities.
Plotnikov S., ЯКУБЕНКО Т. В., Ratio et Natura 2024 № 3 (11) Статья 10
The article presents the results of our own research aimed at studying the prospects of using genetic sequencing technologies to identify the risk of having children with genetic abnormalities. ...
Added: May 21, 2026
Андреева О. С., Просвещение, 2023.
Эта книга о том, как воспитать финансово грамотных детей. Не так важно, какой уровень дохода в вашей семье: умение зарабатывать, сберегать и тратить поможет вашим детям достичь благополучия в будущем. Все необходимые навыки для реальной сложной и порой трудной жизни вы должны вложить в детей сами.
Эта книга – пособие, которое поможет родителям понятно, последовательно и ...
Added: May 18, 2026
Андреева О. С., Росмэн-Пресс, 2026.
«Деньги. Энциклопедия российского школьника» кратко и емко расскажет:
· Чем в древности платили за товары
· Как выглядели первые деньги, из чего их делали и где хранили
· Как найти клад и можно ли выиграть в лотерею
· Как работает банк
· Как дети и подростки могут зарабатывать и распоряжаться личным бюджетом
· И еще сотни интересных научно-обоснованных фактов
Книга поможет мальчикам ...
Added: May 18, 2026
Андреева О. С., Просвещение, 2024.
В книге собраны рекомендации и практические советы приёмным родителям, с помощью которых можно сформировать у детей правильное отношение к денежным средствам, рассказывается, какими словами объяснять понятные взрослым истины относительно личных и семейных финансов ребёнку любого возраста. Одной из задач книги стала необходимость объяснения этого феномена — потребительского отношения приёмных детей к труду замещающих родителей, к ...
Added: May 18, 2026
Карцева М. А., Peresetsky A., / Высшая школа экономики. Серия WP2 "Количественный анализ в экономике". 2026. № WP2/2026/01.
This study examines the association between health status among elderly individuals living alone and pet ownership (cats, dogs). We employ data from the “Time Use Survey” conducted by the Federal State Statistics Service (Rosstat) in 2019, which contains information on more than 10,000 elderly individuals living alone aged 60 or older in Russia, including data ...
Added: May 8, 2026
Perevoznyuk G., Batov A., Pleskovskaya A. et al., Scientific Reports 2026 Vol. 16 Article 13098
Motor imagery (MI) allows individuals to mentally simulate movements without execution, engaging neural pathways that overlap with those used during real actions. However, how imagery perspective influences corticospinal excitability across different effectors remains unclear. Using neuronavigated transcranial magnetic stimulation (TMS), we compared kinesthetic (KMI), first-person visual (VMI-1PP), and third-person visual (VMI-3PP) imagery of elbow flexion-extension ...
Added: May 5, 2026
Sosnin E. I., Vasil’ev Y. L., R.A. Solovyev et al., Computer Optics 2025 Vol. 49 No. 6 P. 1129–1137
In this article, we present a new unique dataset for dental research – AlphaDent. This dataset is based on the DSLR camera photographs of the teeth of 295 patients and contains over 1200 images. The dataset is labeled for solving the instance segmentation problem and is divided into 9 classes. The article provides a detailed ...
Added: May 4, 2026
Назаренко А. Г., Федоров М. В., Moshkin A. et al., Вестник Росздравнадзора 2026 № 1 С. 14–29
Multimodal foundation models and medical multimodal large language models are establishing a new class of diagnostic clinical decision support systems capable of operating on heterogeneous data sources, including medical imaging (X-ray, CT, MRI, ultrasound, histopathology), physiological signals (ECG, EEG), clinical text (electronic health records, reports, discharge summaries), laboratory measurements, molecular profiling data, and related modalities. ...
Added: May 4, 2026
Sorokina I., Социологические исследования 2026 № 4 С. 31–42
This article examines conceptual and terminological inconsistencies in studies of job
quality, quality of employment, and quality of working life within English- and Russian- language academic
literature. Through a systematic review of publications, the study examines key concepts such as job
quality, quality of employment, decent work, and quality of working life, identifying their conceptual
distinctions, disciplinary specificities, and ...
Added: May 2, 2026
Radygina A., Zaripova J., Semenova D. et al., FRONTIERS IN NUTRITION 2026 Vol. 13 Article 1741707
This paper introduces a novel, open-access dataset designed to advance research into early childhood eating behaviors and their familial determinants. The dataset integrates anthropometric measurements (weight, height, age, BMI, and Estimated Energy Requirement) from 203 children aged 4–14 years alongside rich, granular data on food selection behaviors gathered via Dish-I-Wish—a custom, gamified web application developed ...
Added: April 24, 2026
Kashevnik A., Glekler E., Artemenko E. et al., Scientific data 2026 Article 7209
We present a multimodal dataset containing electroencephalography (EEG), electrocardiography (ECG), and video recordings from 49 participants. Each participant completed a single session lasting approximately 45 minutes. During each session they performed five tasks: resting state, inward concentration (focusing on the center of the forehead), outward concentration (visual search), and mind-wandering. EEG data were recorded from ...
Added: April 23, 2026
Kopoleva E., Sergey A. Tsymbal, Kuchur O. et al., Drug Delivery and Translational Research 2026 P. 1–16
Multidrug resistance (MDR) remains one of the principal challenges in cancer chemotherapy, necessitating new strategies to restore drug efficacy. In this study we developed and characterize a redox-responsive nanoplatform based on trithiocyanuric acid and polyethylene glycol (TTCA-PEG NPs) as a potential tool to overcome MDR and provide a biocompatible delivery system for conventional antitumor drugs. ...
Added: April 20, 2026
Makarova M., Fedosov N., Mikhailova I. et al., FRONTIERS IN SIGNAL PROCESSING 2026 Vol. 6 Article 1776807
Introduction:
While self-referential attention is thought to enhance interoceptive sensitivity, its effect on cardiac modulation of corticospinal excitability remains unexplored. This pilot study investigated how viewing one’s own face (self-face processing) modulates the cardiac-phase coupling of motor output and whether this heart-brain coupling depends on interoceptive accuracy (heartbeat perception).
Methods:
In 15 healthy adults, motor-evoked potentials (MEPs) were ...
Added: April 17, 2026
Pogodaeva S. S., Miletina O. O., Mammadova L. V. et al., Frontiers in Bioscience - Landmark 2026 Vol. 31 No. 4 Article 48544
Background: Neuroblastoma (NB), a transcriptionally driven pediatric malignancy, exhibits a remarkable clinical and biological heterogeneity. Two major subtypes, adrenergic and mesenchymal, are differentially governed by distinct subsets of transcription factors that constitute the core regulatory circuitry (CRC). The adrenergic subtype is often associated with MYCN amplification and is particularly aggressive and therapy-resistant, underscoring the need ...
Added: April 15, 2026
Chernov I., Protas A., Popova E. et al., Biochemistry. Biokhimiia 2025 Vol. 19 No. 3 P. 279–287
This article reports the synthesis, characterization, cytotoxic activity, DNA binding study and antioxidant activity of N-(2-(2-(2-azidoethoxy)ethoxy)ethyl)-4,6-di(aziridin-1-yl)-1,3,5-triazin-2-amine. The synthesized compound was found to possess cytotoxic effects against six various cancer cell lines including HeLa, HCT116, T96G, A549, MCF7, and PANC-1 and non-cancer ECV cell line. Additionally, the capacity for DNA binding was assessed. The addition of 1,3,5-triazine ...
Added: April 15, 2026
Chernov K., Savin A., Otvodnikova D. et al., Oncology Research 2026 Vol. - No. -
The formation of drug resistance poses the ultimate threat in modern oncology. Targeted therapy lacks versatility, while conventional therapy is famous for its side effects. However, for the new therapeutics to address the challenge of drug resistance, such compounds should combine properties of both modalities. In this review, we argue that metal-based therapeutics are paramount ...
Added: April 15, 2026
Chernov K. V., Savin A. M., Otvodnikova D. E. et al., Oncology Research 2026 Vol. 34 No. 5 P. 1–40
The formation of drug resistance poses the ultimate threat in modern oncology. Targeted therapy lacks versatility, while conventional therapy is famous for its side effects. However, for the new therapeutics to address the challenge of drug resistance, such compounds should combine properties of both modalities. In this review, we argue that metal-based therapeutics are paramount ...
Added: April 15, 2026
Barskaya E. S., Savin A. M., Chernov K. V. et al., International Journal of Molecular Sciences 2026 Vol. 27 No. 6 Article 2800
Copper–organic compounds are being investigated as antitumor candidates. Besides their efficacy as cytotoxic agents alone, the oxidative potential of electrochemical Cu2+-to-Cu1+ transition emerges as an attractive approach for elimination of tumor cells otherwise resistant to chemotherapy. To minimize side effects of the potent oxidative burst upon Cu(II) reduction, the metal cations should be delivered to the ...
Added: April 15, 2026
Victoria Sakevich, Denisov B., Демографическое обозрение 2024 Vol. 11 No. 3 P. 67–87
The article presents a spatial analysis of abortion rates in Russia. The study draws on official abortion statistics, which, following methodological revisions in 2018, now include information that was not available in previous years. Regional differences are examined in terms of the incidence of induced and spontaneous abortions, the share of abortions performed in the ...
Added: April 9, 2026
Begicheva A., Бегичева С. В., Прикладная информатика 2025 Т. 20 № 5 (119) С. 4–21
Territorial inequality in access to healthcare remains a pressing issue for the healthcare system of the Russian Federation. Significant disparities in transport accessibility, staffing levels, and the spatial distribution of medical facilities complicate evidence-based decision-making, especially in regions with uneven population density and fragmented infrastructure. This creates the need for formalized and reproducible approaches to ...
Added: March 30, 2026
Maiukova E., Kudryashov M., Gorbunova E. et al., Современная зарубежная психология 2026 Т. 15 № 1 С. 68–84
Context and relevance. The psychological well-being of students has become a key priority in the university environment, as it is closely linked to successful adaptation, academic performance, and mental health. Despite the growing number of studies in this field, there is still no systematic understanding of the factors that influence different aspects of student well-being. Objective. ...
Added: March 28, 2026
Бегичева С. В., Begicheva A., Прикладная эконометрика 2026 № 1(81) С. 117–139
The article examines the factors of spatial accessibility of outpatient healthcare at the municipal level. The study is based on data from 65 municipalities of Sverdlovsk Region for the year 2021. A modified gravity-based accessibility index was applied, accounting for the distribution of medical personneland the transport connectivity of territories. The impact of explanatory factors ...
Added: March 27, 2026
Изнак Е. В., Дамянович Е. В., Береснева А. Ф. et al., Психиатрия 2024 Т. 22 № 6 С. 27–33
Background: the need to study and clarify the neurobiological basis of depression is due to the widespread prevalence and heavy socioeconomic burden of this disease. In order to prevent relapses, it is recommended to continue treatment for depression for a long time after the relief of the main depressive symptoms. The study of neurobiological pathways ...
Added: March 20, 2026
Изнак А. Ф., Изнак Е. В., Дамянович Е. В. et al., Журнал неврологии и психиатрии им. С.С. Корсакова 2024 Т. 124 № 9 С. 100–103
Objective. To search for neurophysiological correlates of the characteristics of the brain functional state in patients with endogenous depression with an ultra-high risk of developing psychosis in comparison with EEG parameters of patients without symptoms of a risk of developing psychosis and patients who have suffered psychotic episode. Material and methods. The study included 92 ...
Added: March 20, 2026