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September 7, 2026
Biologists Discover 'Molecular Fingerprint' of Preeclampsia
Researchers at HSE University employed a new method to model hypoxia in placental cells during pregnancies complicated by preeclampsia and identified molecular markers of tissue hypoxia. Since hypoxia is one of the key mechanisms underlying preeclampsia, these findings are important for a more accurate and timely diagnosis of the disease and for the development of effective treatment methods. The paper has been published in Placenta.
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Would you like to know whether a speaker’s trembling voice or an accidental gesture can give them away? At HSE University in Nizhny Novgorod, researchers are developing an algorithm that analyses speech, facial expressions, and gestures, and determines whether information is truthful with 92% accuracy. The project has applications ranging from forensic examination and bank recruitment to fundamental research. Anna Khomenko, head of the research group and Senior Research Fellow at the Centre for Language and Brain at the HSE Faculty of Humanities in Nizhny Novgorod, explains how students and researchers are working together to create a corpus of video recordings, train a classifier, and prepare to introduce computer vision technology.
September 4, 2026
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Advanced Fiber-Coupled Diode Laser Sensor for Calibration-Free 1f-WMS Determination of an Absorption Line Intensity

Sensors. 2020. Vol. 20. No. 21. Article 6286.
Liger V., Mironenko V., Kuritsyn Y., Bolshov M.

Abstract: A new scheme for a calibration-free diode laser absorption spectroscopy (DLAS) sensor for
measuring the parameters of harsh zones is proposed. The key element of the scheme is a micro-prism
retroreflector (MPRR). The MPRR facilitates an increase in the mechanical stability of the sensor and
a decrease in the background thermal radiation in the hot areas of a tested zone. Reduction in the
broadband thermal emission allowed the application of a differential logarithmic conversion (LC)
technique for elimination of the residual amplitude modulation and other sources of non-selective
attenuation of the probing laser beam. LC allows the use of a 1f -wavelength modulation spectroscopy
(WMS) detection scheme. Combination of LC and a 1f-WMS algorithm provided a new modification
of calibration-free DLAS, which could be particularly useful for probing harsh zones with pronounced
strong turbulence and high levels of acoustic and electrical noise. The influence of the experimental
parameters and characteristics of the main electronic components of the recording and processing
system on the accuracy of the integral line intensity determination is investigated theoretically and
experimentally. The proposed optical scheme of a DLAS sensor and algorithm for the data processing
allowed the integral intensity of an absorption line to be obtained. The potential for the scheme was
exemplified with a single water vapor absorption line at 7185.6 cm-1. Simultaneous detection of
several absorption lines and data processing using the developed algorithm provides the final goal of
a DLAS sensor—determination of temperature and partial pressure of a test molecule in a probed gas
volume. The developed scheme allows the spatial multiplexing of the radiation of di erent diode
lasers (DLs), which can be used if various test molecules are to be detected, or absorption lines of a
test molecule are detected over di erent wavelength intervals.

Research target: Physics
Language: English
Full text
DOI
Keywords: absorption spectroscopyDiode laser calibration-freewavelength modulationfirst harmonicretroreflectorlogarithmic processingДиодная лазерная абсорбционная спектроскопиямодуляция длины волныпервая гармоникаретрорефлектор
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