Comparing the development of border regions with the use of GIS (the case of Russia)
The objective of the paper is to analyze the trends and the dynamics of socio-economic development in the areas on both sides of all Russia's land boundaries (more than 22,000 km long) using remote sensing data and GIS applications at different scales. The originality of this research is in the processing of large amounts of data (30 meters resolution images and medium-scale topographic maps) on vast areas and the construction of maps allowing analyzing the data on a new scale. The peripheral character of most border areas is a serious challenge for the development of cross-border cooperation. Depopulation and the depressed state of their economy do not stimulate contacts between neighboring territories. The authors assess the socio-economic situation on both sides of Russian borders and the contrasts between neighboring territories in the mirror of the structure and the dynamics of land use and the density of settlements and roads. The authors come to the conclusion that the border space experiences further fragmentation. The processes on the 'new' (post-Soviet) and 'old' borders differ by their speed and the character of transformations. Their asynchrony is quickly increasing the asymmetry of cross-border interactions.
This article consists of a series of short essays dedicated to a certain chapter of the 'popular' socioeconomic history (with a particular focus on the institutional development problems) of the former East Prussia from the Antiquity to present days. The authors tackle the issues of the economic history of amber, the role of the Hanse in the development of medieval trade, the QWERTY-effects in rail rack standards, and the peculiarities of the development of the Kaliningrad region in the post-Soviet period.
The collective monograph prepared on the basis of the International Scientific-Practical Conference "Social and economic problems of modernization of contemporary society", organized by the Eurasian international scientific and analytical magazine "Problems of the modern economy", the Center for Problem Analysis and the Governance at the Department of Social Sciences, the Academy of Arts of Sciences, St.Petersburg branch of the National Research University "Higher Scool of Economics" in May 2011 in St.Petersburg.
The seven sections of the monograph presents the results of theoretical and applied research scientists on the main areas of socio-economic modernization of the society at the national, regional, sectoral level and at the level of the firm.The guestions of priority setting, study and formation of goals, objectives and implementation mechanisms of modernization processes of socio-economic system. The ways and means of improving the management of national and regional resources as the basic components of modernization.
Scientific publication is intended for a wide range of researchers and experts in the field of socio-economic processes and governance, as well as employees of vocational education.
The article discusses possibilities of socio-economic development of North-Western Federal okrug and formulates the aims and strategic tasks of this development.
Global climate change entails both threats and new opportunities for social and economic development of the Altai-Sayan Ecoregion. Taking into account the scale of climate change forecasted for the ASE, the importance of Altai-Sayan as one of the world’s biodiversity hotspots as well as an important role assigned to the region in strategic plans of Russia’s economic development, the need to develop regional measures of adaptation to both negative and positive impacts of climate change raises no doubts. In particular, climate change is referred to as a new determinant of development and a security challenge to Russia and its regions in such strategic documents as: the RF Environmental Doctrine (2002), the RF Long-Term Social and Economic Development Concept for the period to 2020 (2008), the RF Forest Complex Development Strategy for the period to 2020 (2008), the RF National Security Strategy for the period to 2020 (2009), the RF Climate Doctrine (2009), the Energy Strategy of Russia for the period to 2030 (2009), the RF Food Safety Doctrine (2010) and the Strategy of Social and Economic Development of Siberia for the period to 2020 (2010).
One of the key advances in genome assembly that has led to a significant improvement in contig lengths has been improved algorithms for utilization of paired reads (mate-pairs). While in most assemblers, mate-pair information is used in a post-processing step, the recently proposed Paired de Bruijn Graph (PDBG) approach incorporates the mate-pair information directly in the assembly graph structure. However, the PDBG approach faces difficulties when the variation in the insert sizes is high. To address this problem, we first transform mate-pairs into edge-pair histograms that allow one to better estimate the distance between edges in the assembly graph that represent regions linked by multiple mate-pairs. Further, we combine the ideas of mate-pair transformation and PDBGs to construct new data structures for genome assembly: pathsets and pathset graphs.
Papers about natural protection territories
Many environmental stimuli present a quasi-rhythmic structure at different timescales that the brain needs to decompose and integrate. Cortical oscillations have been proposed as instruments of sensory de-multiplexing, i.e., the parallel processing of different frequency streams in sensory signals. Yet their causal role in such a process has never been demonstrated. Here, we used a neural microcircuit model to address whether coupled theta–gamma oscillations, as observed in human auditory cortex, could underpin the multiscale sensory analysis of speech. We show that, in continuous speech, theta oscillations can flexibly track the syllabic rhythm and temporally organize the phoneme-level response of gamma neurons into a code that enables syllable identification. The tracking of slow speech fluctuations by theta oscillations, and its coupling to gamma-spiking activity both appeared as critical features for accurate speech encoding. These results demonstrate that cortical oscillations can be a key instrument of speech de-multiplexing, parsing, and encoding.
Neuronal nicotinic acetylcholine receptors (NNRs) of the α7 subtype have been shown to contribute to the release of dopamine in the nucleus accumbens. The site of action and the underlying mechanism, however, are unclear. Here we applied a circuit modeling approach, supported by electrochemical in vivo recordings, to clarify this issue. Modeling revealed two potential mechanisms for the drop in accumbal dopamine efflux evoked by the selective α7 partial agonist TC-7020. TC-7020 could desensitize α7 NNRs located predominantly on dopamine neurons or glutamatergic afferents to them or, alternatively, activate α7 NNRs located on the glutamatergic afferents to GABAergic interneurons in the ventral tegmental area. Only the model based on desensitization, however, was able to explain the neutralizing effect of coapplied PNU-120596, a positive allosteric modulator. According to our results, the most likely sites of action are the preterminal α7 NNRs controlling glutamate release from cortical afferents to the nucleus accumbens. These findings offer a rationale for the further investigation of α7 NNR agonists as therapy for diseases associated with enhanced mesolimbic dopaminergic tone, such as schizophrenia and addiction