Molecular mechanisms of synthesis of noradrenaline as an inducer of development in the adrenal glands of rats in ontogenesis
The level of gene expression and the protein content of tyrosine hydroxylase and dopamine β-hydroxylase were determined. In the perinatal period of rats, when noradrenaline functions as a morphogenetic factor, the level of gene expression of these enzymes increased and the content of protein products of these genes was almost unchanged, indicating the difference in the regulatory mechanisms of their transcription and translation.
Original Russian Text © N.S. Bondarenko, A.R. Murtazina, Yu.O. Nikishina, A.Ya. Sapronova, M.V. Ugrumov, 2017, published in Doklady Akademii Nauk, 2017, Vol. 472, No. 3, pp. 341–344.