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2020 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)
Seul :
IEEE, 2020.
The IEEE International Conference on Bioinformatics and Biomedicine (BIBM) has established itself as the premier research conference in bioinformatics and biomedicine. IEEE BIBM 2020 provides a leading forum for disseminating the latest research in bioinformatics and health informatics. It brings together academic and industrial scientists from computer science, biology, chemistry, medicine, mathematics and statistics.
Chapters
Pavlov F., Poptsova M., , in: 2020 IEEE International Conference on Bioinformatics and Biomedicine (BIBM).: Seul: IEEE, 2020. P. 2800–2805.
Added: March 29, 2021
Beknazarov N., , in: Parallel Computational Technologies, 19th International Conference, PCT 2025, Moscow, Russia, April 8–10, 2025, Revised Selected Papers. (CCIS, volume 2891)Vol. 2891.: Springer, 2026. P. 3–16.
This paper addresses the challenge of efficiently training Large Language Models (LLMs) on large-scale, sparse omics datasets in high-performance computing (HPC) environments. Using over 1000 BED tracks as a representative data source, we propose a method combining interval-based chunked storage, sparse matrix transformation, and parallel data loading, integrated within a PyTorch Lightning training framework. Our ...
Added: May 19, 2026
Goltseva Y., Tsokolaeva Z., Beloglazova I. et al., Stem Cell Research and Therapy 2026 Vol. 17 No. 1 Article 112
Background Cardiac fibrosis represents a significant health burden, with endothelial dysfunction and damaged
perivascular microenvironment increasingly recognized as key contributors to fibrotic remodeling. The urokinase
plasminogen activator receptor (uPAR), a critical component of the urokinase system, plays a pivotal role in vascular
remodeling and fibrosis. While prior evidence indicates that uPAR deficiency leads to microvascular dysfunction and
perivascular fibrosis, ...
Added: May 19, 2026
NY: Association for Computing Machinery (ACM), 2026.
It is our great pleasure to welcome you to the 35th edition of the Web Conference to be held on June 29 – July 3, 2026, in Dubai, United Arab Emirates.
Following discussions with our partners and key stakeholders, we have taken the decision to postpone the ACM Web Conference 2026, initially planned for April 2026. ...
Added: April 23, 2026
Pogodaeva S., Miletina O., Antipova N. et al., Cancers 2025 Vol. 17 No. 19 Article 3228
Pediatric tumors such as neuroblastoma are characterized by a genome-wide ‘transcriptional burden’, surmising the involvement of multiple alterations of gene expression. Search for master regulators of transcription whose inactivation is lethal for tumor cells identified the non-POU domain-containing octamer-binding protein (NONO), a member of the Drosophila Behavior/Human Splicing family known for the ability to form ...
Added: April 15, 2026
Chernov K. V., Savin A. M., Otvodnikova D. E. et al., Oncology Research 2026 Vol. 34 No. 5 P. 1–40
The formation of drug resistance poses the ultimate threat in modern oncology. Targeted therapy lacks versatility, while conventional therapy is famous for its side effects. However, for the new therapeutics to address the challenge of drug resistance, such compounds should combine properties of both modalities. In this review, we argue that metal-based therapeutics are paramount ...
Added: April 15, 2026
Barskaya E. S., Savin A. M., Chernov K. V. et al., International Journal of Molecular Sciences 2026 Vol. 27 No. 6 Article 2800
Copper–organic compounds are being investigated as antitumor candidates. Besides their efficacy as cytotoxic agents alone, the oxidative potential of electrochemical Cu2+-to-Cu1+ transition emerges as an attractive approach for elimination of tumor cells otherwise resistant to chemotherapy. To minimize side effects of the potent oxidative burst upon Cu(II) reduction, the metal cations should be delivered to the ...
Added: April 15, 2026
S. V. Nikulin, Olkhovik D., A.V. Razumovskaya et al., Doklady Biochemistry and Biophysics 2026 Vol. 526 P. 59–64
A novel trend in anticancer therapy is based on the combination of cytotoxic and metabolic drugs. Bach1 is a transcription factor activating glycolysis and increasing proliferation and metastatic potential in cancer cells. The cytotoxic effect was evaluated for a combination of rotenone, an inhibitor of mitochondrial respiration, and two different inhibitors of Bach1 transcription factor ...
Added: April 13, 2026
Zolotova N., Kirillova M., Dzhalilova D. et al., International Journal of Molecular Sciences 2025 Vol. 26 No. 23 Article 11511
Recently, evidence indicating that microplastics (MPs) have a hazardous effect on human health is accumulating. The potential of MPs having a role in carcinogenesis was suggested. Therefore, the aim of this study was to evaluate MPs’ effect on colitis-associated colorectal cancer (CAC) development. The AOM/DSS-induced CAC model was reproduced in two groups of adult male ...
Added: March 24, 2026
Silina M., Dzhalilova D., Fokichev N. et al., Frontiers in Molecular Biosciences 2025 Vol. 12 Article 1674608
Humans and laboratory animals differ in their resistance to hypoxia, which affects the severity of inflammatory diseases and the rate of tumor progression. Therefore, it is necessary to search for methods for assessing the initial tolerance to oxygen deficiency and the risks of developing acute mountain sickness without direct hypoxia exposure on the organism. The ...
Added: March 24, 2026
Shchetinin I., Nikolenko P., Nizamov T. et al., Ceramics International 2026 Vol. 52 No. 3 P. 3500–3511
In this work, we comprehensively investigated the influence of Indium doping on the structure, magnetic and functional properties of strontium M-type hexaferrites SrFe12-xInxO19 nanoparticles (where x = 1.7, 1.8, 2.0). Colloidally stable SrFe12-xInxO19 nanoparticles (∼10 nm) were synthesized using a combination of the citrate method and high-energy ball milling. We demonstrate that doping reduces both the specific saturation magnetization and, ...
Added: March 16, 2026
Mungalov R. V., Vand N. S., Chudakov D. M. et al., Биоорганическая химия 2025 Т. 51 № 5 С. 1827–1837
The development of therapeutic antigen-specific T-cell receptors (TCRs) requires comprehensive preclinical validation of their functional activity. One of the approaches in the development of new drugs for cell therapy based on antigen-specific T lymphocytes is the modification of autologous T lymphocytes with endogenous T-cell receptors. The present work reviews modern laboratory platforms used to assess ...
Added: March 4, 2026
Roman V. Mungalov, Mushenkova N., Chudakov D. et al., Frontiers in Immunology 2025 Vol. 16 Article 1551424
T-cell engagers represent a transformative approach to cancer immunotherapy leveraging bispecific and multispecific antibody constructs to redirect T-cell cytotoxicity toward malignant cells. These molecules bridge T cells and tumor cells by simultaneously binding CD3 on T cells and tumor-associated antigens on cancer cells, thereby enabling precise immune targeting even in immunologically “cold” tumors. Recent advancements ...
Added: March 4, 2026
Алматы: Институт информационных и вычислительных технологий КН МНВО РК, 2024.
The collection contains papers presented by scientists from the Republic of Kazakhstan, the Russian Federation, Latvia, Poland, the Republic of Belarus, Japan, Iran, Malaysia, the Kyrgyz Republic, the Republic of Uzbekistan, and others. It addresses current issues in mathematics, computer science, and management, including mathematical modeling of complex systems and business processes, research and development ...
Added: March 3, 2026
Садовская Я. О., Гусев Д. В., Karimova A. et al., Российский онкологический журнал 2025 Т. 30 № 3 С. 247–258
Обоснование. Активаторы STING с направленной доставкой в опухолевые узлы обладают высоким потенциалом в иммунотерапии рака, особенно в формате иммуноконъюгатов. Известные соединения, такие как MSA-2, не обладают достаточной активностью для их использования в качестве активной составляющей иммуноконъюгата, поэтому требуется разработка новых, более активных соединений.
Цель. Изучение биологической активности нового соединения SAD-2 и оценка его перспективности с целью ...
Added: February 19, 2026
Karimova A., Садовская Я. О., Солопова О. Н., Российский онкологический журнал 2025 Т. 30 № 3 С. 156–169
ABSTRACT Modern oncology needs to develop and implement antineoplastic agents that provide sustained remission without serious side effects. Immunotherapy and targeted therapy agents that activate innate immunity may address this issue. The stimulator of interferon genes (STING), an intracellular protein, mediates the synthesis of type I interferons, which have antiviral, antitumor, and antiproliferative properties. The ...
Added: February 19, 2026
Arteaga Moreano B. D., Chervov N., Poptsova M., Scientific Reports 2026 Vol. 16 No. 1 Article 4772
Accurate prediction of protein-protein interactions (PPIs) is fundamental to understanding biological processes and disease mechanisms. While deep learning offers a powerful alternative to costly experimental methods, existing approaches often overlook critical protein-surface information and rely on simplistic feature fusion techniques, thereby limiting performance. To address this, we introduce GSMFormer-PPI, a novel multimodal framework that integrates ...
Added: February 4, 2026
Portnova G., Proskurnina E., Liaukovich K. et al., Journal of Molecular Neuroscience 2026 Vol. 76 Article 19
This study investigates the relationship between stress coping ability, salivary antioxidant capacity (AOC), and trace element concentrations, focusing on zinc (Zn) and potassium (K). A cohort of 73 participants, divided into groups based on stress coping ability (SCA) (“adaptive”, “intermediate”, and “maladaptive”), underwent cognitive tasks while physiological and behavioral data were collected. Saliva samples were ...
Added: February 2, 2026
Obiedkov S., Switzerland: Springer, 2024.
This book constitutes the proceedings of the First International Joint Conference on Conceptual Knowledge Structures, CONCEPTS 2024, which took place in Cádiz, Spain, during September 9-13, 2024. The conference is an amalgamation of the 18th International Conference on Formal Concept Analysis (ICFCA); the 17th International Conference on Concept Lattices and Their Applications (CLA); and the 28th ...
Added: January 23, 2026
I. A. Khaustov, Yu. A. Safronova, O. E. Chebotareva et al., Applied Biochemistry and Microbiology 2025 Vol. 61 No. 9 P. 1753–1759
Polydimethylsiloxane (PDMS) remains one of the most popular materials for microfluidic chips, but its high gas permeability can lead to the formation of gas bubbles in microchannels, which hampers the reproducibility of experiments in organ-on-a-chip systems. The dependence of the gas permeability of PDMS on the ratio of base to hardener (2.5 : 1, 5 : 1, and ...
Added: December 22, 2025
David Arteaga, Poptsova M., Computational and Structural Biotechnology Journal 2026 Vol. 31 P. 82–93
Accurate predictions and large-scale identification of protein-protein interactions (PPIs) are crucial for understanding their inherent biological mechanisms and protein functions in virtually all biological processes. Nowadays, graph-based deep learning models have made significant contributions in modeling proteins with physicochemical and geometric features. However, most of these models rely on conventional graph construction methods, such as ...
Added: December 22, 2025
Posnenkova O., Simonyan M., Akimova N., Blood Pressure Monitoring 2025 No. 11
We aimed to evaluate the accuracy of B.Well PRO-33 (B.Well, Widnau, Switzerland) oscillometric device for professional office measurement of blood pressure (BP) on the upper arm in the general population in accordance with the Amendment 2.2024-01 of the Standard 81060-2:2018 by the International Organization for Standardization (ISO 81060-2:2018/AMD 2:2024). Study participants were recruited according to ...
Added: December 11, 2025
Silkina M., T.A. Kulagin, K.V. Klycheva et al., Doklady Biochemistry and Biophysics 2026 Vol. 526 P. 11–16
Ferroptosis is considered a promising strategy for inducing the death of tumor cells. However, the effectiveness of known ferroptosis inducers, such as erastin, is in some cases limited, which stimulates the search for new combined application strategies. In this study, the combined effect of erastin and docosahexaenoic acid (DHA) on prostate cancer cells was examined ...
Added: December 11, 2025
Абрамова А. В., Белоусова Е. Н., Ватюков С. Е. et al., Проблемы стандартизации в здравоохранении 2025 № 5-6 С. 3–14
The improvement of artificial intelligence (AI) technologies and their rapid integration into the socially and economically significant medical industry create broad prospects for ensuring accessibility and quality of medical care, while at the same time creating new challenges related to the safety and ethical risks of using innovative solutions. This creates the need to develop ...
Added: December 7, 2025
Antipenko I., Knyazev E., Timur Kulagin et al., Frontiers in Molecular Biosciences 2025 Vol. 12 Article 1731126
Preeclampsia is a leading cause of maternal and perinatal morbidity associated with systemic lipid metabolism disturbances, yet the underlying molecular mechanisms remain incompletely understood. In this study, we integrated single-cell RNA-seq data from preeclamptic placentas with an in vitro hypoxia model to analyze gene expression changes across distinct trophoblast subpopulations. While all trophoblast lineages exhibited ...
Added: December 2, 2025