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Изотермическая петлевая амплификация - перспективный метод массовой диагностики COVID-19
Биотехнология. 2020. Т. 36. № 5. С. 6–12.
Makarova J., Фомичева К. А., Осипьянц А. И., Шкурников М. Ю., Покрыщенко А. А., Тоневицкий Е. А., Вечорко В. И.
Real-time RT-PCR currently remains a gold standard for early COVID-19 diagnostics. However
Loop-mediated isothermal amplification (LAMP) method outperform real-time RT-PCR in simplicity
because it doesn't require expensive lab equipment and trained personnel, and in speed. LAMP-based
diagnostic kits for COVID-19 testing are already exist, but LAMP-based tests have not been widely
accepted yet. The method has great potential for massive diagnostics. Here we discuss technical and
methodological aspects of its wide implementation.
Liaukovich K., Panfilova E., Khayrullina G. et al., International Journal of Psychophysiology 2025 Vol. 207 P. 112475
Added: September 5, 2026
Portnova G., Liaukovich K., Sharaev M., Cognitive Neurodynamics 2025 Vol. 19 Article 181
Added: September 5, 2026
Liaukovich K., Bainbridge E., Khayrullina G. et al., Neuroscience and Behavioral Physiology 2026 Vol. 56 P. 10–19
Added: September 5, 2026
Kashevarova O., Portnova G., Khayrullina G. et al., Frontiers in Psychiatry 2026 Vol. 17 P. 1776019
Added: September 5, 2026
Liaukovich K., Martynova O., Brain Sciences 2026 Vol. 5 No. 16 P. 439
Highlights
What are the main findings?
Temporal predictability may enhance auditory frequency discrimination, but only under active listening and when discrimination is difficult; the local irregularity (five-tone bundles) yields higher hit rates and perceptual sensitivity (d’) compared to oddball or two-tone paradigms, accompanied by enhanced P300 amplitude.
Participants may show a dissociation between objective performance and subjective awareness: ...
Added: September 4, 2026
Кубкин Я. В., Российский кардиологический журнал 2026 Т. 31 № 8S
Goal. To assess the contribution of polygenic risk scores to the short‑term mortality prediction model in patients with dilated cardiomyopathy (DCM).
Materials and methods. The study included 137 patients with DCM. The mean age was 56.8 ± 13.5 years; there were 115 men (83.9 %). The median follow‑up period was 17 [13; 22] months. During the follow‑up period, 26 ...
Added: August 24, 2026
Лукьяненко Д. В., Ragimova A., Мухорина А. et al., European Physical Journal: Special Topics 2026 P. 1–24
Electronic health records (EHRs) contain vast volumes of clinical information that encode complex relationships between diseases. Traditional approaches to the analysis of interrelated or co-occurring diseases have focused on pairwise associations between diagnoses, missing the higher-order structures that characterise multimorbid patients. The present paper offers a narrative review of existing statistical, machine-learning, and artificial intelligence ...
Added: August 20, 2026
Moshkin A., Fedorov M., Arlazarov V. et al., Algorithms 2026 Vol. 19 No. 7 Article 523
Artificial intelligence (AI) technologies, which are being actively developed in modern medicine today, increase the speed and quality of patient care. This article mainly seeks to demonstrate the use of various options of computer analysis of clinical images to solve practical problems of increasing the efficiency of routine diagnostics using retrospective analysis, as well as ...
Added: August 17, 2026
Badarin A., Ratnikov F., Andreev A., European Physical Journal: Special Topics 2026 P. 1–10
EEG recordings are often affected by the loss or corruption of individual channels due to electrode detachment, poor scalp contact, or external interference. Such channels must be accurately reconstructed before further analysis. In this study, we investigate Next-Generation Reservoir Computing (NG-RC) as a data-driven approach for reconstructing corrupted EEG channels and compare its performance with ...
Added: August 12, 2026
Dmitrova E., Буклина С. Б., Gronskaya N. E. et al., Вопросы нейрохирургии им. Н.Н. Бурденко 2026 Т. 90 № 4 С. 87–94
Effective intraoperative speech mapping requires specific test with standardized linguistic material. The last one should capture speech function supported by brain region targeted for resection. It is necessary to develop a test tailored to specific patient’s needs and document intraoperative linguistic support. The objective of this report was to describe the procedure of intraoperative speech testing and battery of intraoperative tests for Russian language. We correlated intraoperative tests with brain regions and speech functions, as well as presented an application ...
Added: August 12, 2026
Lucas J., Hebbar P., Ryabov F. et al., / Series 10.64898/2026.07.21.739710 "10.64898/2026.07.21.739710". 2026.
A pangenome reference overcomes the inherent limitation of any individual reference genome by integrating the variation present in a population. We present the Human Pangenome Reference Consortium’s (HPRC) Release 2 (HPRC2), an openly available, second phase pangenome that is an approximately fivefold expansion in genome number over HPRC Release 1 (HPRC1) and measurable improvement in ...
Added: August 10, 2026
Rakhlin N., Li N., Momotenko D. et al., American Journal of Speech-Language Pathology 2026 P. 1–18
Purpose:
We (a) investigated whether children of lower socioeconomic status (SES) are at a greater risk of developmental language disorder (DLD) than children of higher SES, based on standardized assessment; (b) identified the language skills most strongly affected by SES; and (c) examined which standardized and naturalistic measures best differentiate DLD in children from lower SES ...
Added: August 10, 2026
Sandlerskiy R., Elsevier, 2026.
Encyclopedia of Ecology, Third Edition, Four Volume Set - with over 300 chapters - once again provides a comprehensive reference work covering the current ideas and practices in ecology.
Ecology is the ideal field for studying complex, adaptive, and self-organizing systems and by observing and understanding ecosystems, it provides valuable insights into creating sustainable systems. This knowledge is ...
Added: August 9, 2026
Dadinova L., Petoukhov M., Mozhaev A. et al., Crystallography Reports 2026 Vol. 71 P. 52–58
Bacterial chromosomes are tightly packed in the cells due to interactions with specific nucleoid-associated proteins. Among them, the IHF protein draws attention due to its presumed influence on intracellular crystallization processes, leading to bacterial resistance to drugs. The crystal structure of the IHF heterodimer is known only in complex with a short DNA fragment, whereas ...
Added: August 6, 2026
A. Radygina, S. Kulikova, Herald of the Russian Academy of Sciences 2025 Vol. 95 No. 6 P. 963–970
Musical training has a significant impact on brain organization, leading to functional and structural
adaptations that enhance auditory, visual, motor, and cognitive processes. This study investigates how
extensive musical training shapes functional brain connectivity by comparing professional musicians and
non-musicians. Using EEG phase-locking value (PLV) analysis, we examined neural synchronization across
alpha, beta, and gamma frequency ranges during music ...
Added: August 5, 2026
Provlotskaya I., Minnigulova A., Gordeyeva E. et al., Brain Structure and Function 2026 Vol. 231 Article 113
The Wada test is an invasive procedure used to assess language and memory lateralization. Despite the widespread use of the Wada test in the population of people with epilepsy, the two existing standardized protocols for conducting the procedure are methodologically different and do not fully account for language comprehension as a separate domain. In this ...
Added: August 4, 2026
Mikhaylets E. V., Razorenova A. М., Chernyshev V. L. et al., Scientific Reports 2026 Vol. 16 Article 23560
Meditation offers a naturalistic paradigm for studying introspection, yet the neural dynamics of advanced tantric practices remain largely unexplored. Buddhist Highest Yoga Tantra (BHYT) comprises a sequence of eight dissolution stages culminating in the “clear light” state. We recorded EEG during eyes-closed BHYT meditation performed in monasteries and hermitages (51 sessions from 36 male practitioners; ...
Added: July 29, 2026
Kotyrlo E., Zhang W., Applied Economics 2026
The study investigates the heterogeneity of the effect of COVID-19 pandemic-related restrictions on economic well-being in Russia based on labour market size, socio-demographic groups and income distribution. We examine the effect by composing a group of private-sector workers affected by pandemic-related restrictions in the labour market. We use public-sector workers as a counterfactual. Difference in ...
Added: July 20, 2026
Хайлова Ж. В., Омельяновский В. В., Терян Р. А. et al., Опухоли женской репродуктивной системы 2025 Т. 21 № 1 С. 86–105
Цель исследования – определить наиболее целесообразную стратегию скрининга и ранней диагностики рака шейки матки (РШМ) в Российской Федерации с точки зрения клинической (диагностической) и экономической эффективности.
Материалы и методы. Для оценки клинической (диагностической) эффективности различных стратегий скрининга проведен систематический обзор публикаций об исследованиях, оценивающих эффективность применения цитологического исследования и тестирования на вирус папилломы человека (ВПЧ) с целью диагностики ...
Added: July 16, 2026
Sun Z., Khvostikov A., Krylov A. et al., Machine Learning and Knowledge Extraction 2026 Vol. 8 No. 1 Article 8
Whole-slide histology images (WSIs) can exceed 100 k × 100 k pixels, making direct pixel-level segmentation infeasible and requiring patch-level classification as a practical alternative for downstream WSI segmentation. However, most approaches either treat patches independently, ignoring spatial and biological context, or rely on deep graph models prone to oversmoothing and loss of local tissue ...
Added: July 16, 2026
Turkina A., Vinogradova O., Lomaia E. et al., Annals of Hematology 2025 Vol. 104 P. 2707–2715
Vamotinib (PF-114) is a 3rd -generation, ATP-competitive oral tyrosine kinase inhibitor (TKI) active against wild-type and mutated BCR::ABL1 isoforms including BCR::ABL1T315I. We present final results of a phase-1 vamotinib dose-escalation study to identify maximum tolerated dose (MTD) and dose-limiting toxicity (DLT) followed by expansion cohorts. 51 subjects with chronic myeloid leukaemia (CML) failing ≥ 1 2nd generation TKI or with BCR::ABL1T315I were ...
Added: July 16, 2026
Васильчук М. С., Шаньков Ф. М., Chumakova M. et al., Psychology. Journal of the Higher School of Economics 2021 Vol. 18 No. 2 P. 247–258
The 2019 Coronavirus disease outbreak leads to negative psychological outcomes not only for healthcare workers and patients, but also for the general public. S. Hobfoll’s Conservation of Resources theory is one of the most applicable models for conceptualizing and evaluating natural and social catastrophes and their impact. A web-based screening has been conducted at the ...
Added: June 30, 2026
Levin J., Oprea T. I., Davidovich S. et al., Nature Biotechnology 2020 P. 1127–1131
The COVID-19 pandemic has transformed the way scientific and clinical results are shared and disseminated. According to a recent analysis, an average of 367 COVID-19 papers are being published every week, with a median time from submission to acceptance of just 6 days (compared with 84 days for non-COVID-19 content)1. These unprecedented peer review turnaround ...
Added: June 1, 2026
Dvoynikova A., Маркитантов М. В., Рюмина Е. В. et al., Информатика и автоматизация (Труды СПИИРАН) 2021 Т. 20 № 5 С. 1116–1152
Начиная с 2019 года все страны мира столкнулись со стремительным распространением пандемии, вызванной коронавирусной инфекцией COVID-19, борьба с которой продолжается мировым сообществом и по настоящее время. Несмотря на очевидную эффективность средств индивидуальной защиты органов дыхания от заражения коронавирусной инфекцией, многие люди пренебрегают использованием защитных масок для лица в общественных местах. Поэтому для контроля и своевременного ...
Added: April 24, 2026