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News
July 20, 2026
Scientists Create Open Dataset for Studying Concentration
A team of Russian researchers, including scientists from HSE University–St Petersburg, has developed the first open multimodal dataset containing recordings of brain activity, heart function, and video observations to help researchers understand what happens in the human brain during deep concentration. In the future, the dataset could accelerate the development of neural interfaces, rehabilitation technologies, and AI systems. The article has been published in Scientific Data.
July 20, 2026
‘Science Is Universal-It Knows No Borders
Fuad Aleskerov, Tenured Professor and Director of the International Centre of Decision Choice and Analysis at HSE University, together with his colleagues, has developed methods of network analysis in bibliometrics that have made it possible to identify patterns in the appearance and citation of publications in academic journals, as well as their influence on each other. When one or a number of studies are frequently cited by a wide range of journals, this is an indicator that the research is of high quality. By contrast, extensive cross-citation within a limited group of journals increases the likelihood of identifying a network of predatory publications.
July 20, 2026
Scientists Propose Method for More Efficient Resource Use in Machine Learning
An international group of researchers, including mathematicians from the AI and Digital Science Institute at the HSE Faculty of Computer Science, has provided a theoretical justification for a simple and computationally efficient method of estimating uncertainty in Stochastic Gradient Descent (SGD). The paper has been published on the scientific preprint server arXiv.org and presented at AISTATS 2026.

 

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Систематический обзор оригинальных исследований прогностических свойств белка YB-1 в отношении общей и безрецидивной выживаемости больных раком молочной железы

Value and Outcomes Spotlight. 2015. Т. 20. № 1. С. 1–12.
Генс Г. П., Федяева В. К., Rebrova O.
Priority areas: management
Language: Russian
Keywords: systematic reviewРак молочной железыBreast cancer систематический обзорYB-1disease prognosisoverall survivalprogression free survivalYB-1прогноз заболеванияобщая выживаемостьбезрецидивная выживаемость
Similar publications
Assessing the impact of economic sanctions on the socio-economic development of a sanctioned country -testing a new research approach using the data on the socio-economic development of Russia in 2022-2025
Gurkov I. B., Kossov V. V., Filinov N. et al., / NRU Higher School of Economics. Series MAN "Management". 2026. No. N/A.
This research note is devoted to assessing the socioeconomic impact of sanctions of sanctioned countries and uses the data on Russia in 2022-2024. We use for the analysis four fundamental socioeconomic parameters-the expected length of life of males at birth, the misery index (Okun's index), the level of Gross Domestic Product at purchasing parity prices, ...
Added: June 11, 2026
Оценка клинико-экономической эффективности раннего выявления злокачественных новообразований с помощью наблюдения здоровых носителей высокоонкогенных герминальных мутаций
Бодунова Н. А., Хатьков И. Е., Найговзина Н. Б. et al., Вестник Всероссийского общества специалистов по медико-социальной экспертизе, реабилитации и реабилитационной индустрии 2026 Т. 22 № 1 С. 109–122
Introduction. The increasing incidence and mortality of cancer, along with the growing contribution of hereditary malignancies, necessitate the implementation of personalized prevention models based on molecular genetic risk stratification and early cancer detection among asymptomatic carriers of highly penetrant germline mutations. Aim. The aim of this study was to evaluate the clinical and economic effectiveness ...
Added: April 22, 2026
Global, regional, and national burden of breast cancer among females, 1990–2023, with forecasts to 2050: a systematic analysis for the Global Burden of Disease Study 2023
Bhangdia K., May M. L., Kocarnik J. M. et al., The Lancet Oncology 2026 Vol. 27 No. 3 P. 302–326
Background Breast cancer is a leading cause of mortality and morbidity among females worldwide. As part of the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2023, we provided an updated comprehensive assessment of the epidemiological trends, disease burden, and risk factors associated with breast cancer globally, regionally, and nationally from 1990 to 2023. Methods Breast ...
Added: March 6, 2026
НЕВРОЛОГИЧЕСКИЕ СИМПТОМЫ У ДЕТЕЙ С ДЕБЮТОМ ИШЕМИЧЕСКОГО ИНСУЛЬТА В РАННЕМ ВОЗРАСТЕ: ПРОСПЕКТИВНОЕ ИССЛЕДОВАНИЕ
Троцкая И. А., Львова О. А., Короткова Е. В. et al., В кн.: Медицинское образование, наука, практика : Сборник статей X Международной научно-практической конференции молодых ученых и студентов, 22-23 апреля 2025 г. Т.2.: Екатеринбург: ФГБОУ ВО УГМУ Минздрава России, 2025. С. 673–679.
Pediatric ischemic stroke is considered to be a rare condition. Correct recognition of the acute symptoms and further monitoring of the dynamics of them may allow predicting the child's development and further adaptation. The aim of the study was to provide clinical and imaging features of the acute period of ischemic stroke with debut at an ...
Added: March 2, 2026
Being Innovative or Being on the Safe Side - Managing the Risk of Failure
Meissner D., Salati Marcondes de Moraes G. H., Brandão Fischer B. et al., / NRU Higher School of Economics. Series WP BRP "Science, Technology and Innovation". 2025. No. WP BRP /STI/2025.
Innovation has long been at the center of debates in economics, management, and organizational studies. However, innovation is never free of uncertainty and risk. Every act of innovation implies a departure from established paths and a willingness to embrace the unknown. From the beginning it's never clear if there is an audience which appreciates the ...
Added: November 28, 2025
Enabling the ‘Education Revolution’ through the Sustainability Mindset Principles
Cripps K., Ivanova E., Sridaran K. et al., / Series 0 "0". 2024.
Imagine a world where individuals are considering the impact on the long term of the decisions they are making. Where, as they analyze information, they wonder who are the stakeholders impacted – extending beyond the traditional ones to include Nature, the ecosystem as a stakeholder, and the next generations. Imagine young people reminding each other ...
Added: November 5, 2025
Causal Estimands for Policy Evaluation and Beyond
Sokolov B., / Series OSF "SocArXiv". 2025.
This paper reviews various estimands used in modern scientific and applied research to operationalize causal inquiries within the Rubin Causal Model framework. I first introduce the most widely utilized average treatment effects, such as ATE, ATT, and ATC. I then describe their popular extensions, including those targeting local and conditional treatment effects; causal interactions and mediation; effects ...
Added: May 6, 2025
Divergent ferroptotic pathways in breast cancer cells: IGFBP6-regulated mitochondrial lipid peroxidation under erastin and omega-3 DHA treatment
Silkina M., Razumovskaya A., Timur Kulagin et al., Biochimie 2025 Vol. 234 P. 48–61
Breast cancer remains a major challenge and new therapeutic approaches are needed for its treatment. Ferroptosis is considered a promising alternative cell death mechanism to eliminate resistant cancer cells. In previous works, we identified that lower IGFBP6 gene expression in tumor tissue corresponds to a worse prognosis for breast cancer patients and, at the same, time makes ...
Added: April 9, 2025
Ангедония при расстройствах настроения и соматических заболеваниях: результаты разведочного Менделевского рандомизационного анализа.
Касьянов Е. Д., Пинахина Д. В., Ракитько А.С. et al., Журнал неврологии и психиатрии им. С.С. Корсакова 2023 Т. 123 № 4-2 С. 65–73
Цель исследования. Провести разведочный Менделевский рандомизационный анализ причинных связей ангедонии с широким кругом психиатрических и соматических фенотипов на основе генетических данных участников популяционного исследования. ...
Added: March 4, 2025
Cultural characteristics of Digital Ecosystem Product Teams and Operational Efficiency
Ovanesova Y., Moshiashvili M. M., Типсина Н. О., / Series "Working Papers". 2021.
The purpose of this article is to analyze and evaluate the cultural characteristics of the digital ecosystem product teams leaders and operational efficiency. Using binary choice models (the main conclusions were made on the basis of logit regressions), has been found a significant negative relationship between the probability of achieving business goals by a team ...
Added: February 17, 2025
Забытая классика: теория империализма Й. А. Шумпетера
Kapeliushnikov R., / Высшая школа экономики. Серия WP3 "Проблемы рынка труда". 2024. № WP3/2024/03.
The paper analyses the little-known essay of one of the classics of economic thought, J. A. Schumpeter (1883–1950), “The Sociology of Imperialisms,” where he appears not as an economic theorist, but as an economic sociologist. The problem of imperialism interested Schumpeter almost throughout his scientific career. His theory was polemically directed against various Marxist interpretations, ...
Added: December 18, 2024
Эскалация вакансий на российском рынке труда (динамика, структура, триггеры)
Kapeliushnikov R., / Высшая школа экономики. Серия WP3 "Проблемы рынка труда". 2024. № WP3/2024/02.
The paper explores the key development in the Russian labor market of the 2020s – emergence of a massive overhang of vacant jobs, which has already reached a record level of 7 percent. The paper discusses theoretical aspects of the problem of labor “shortage”, examines probable triggers for the vacancy escalation, and analyzes its dynamics and ...
Added: December 18, 2024
Юность эконометрики: кейнсианцы contra Кейнс
Kapeliushnikov R., / Высшая школа экономики. Серия WP3 "Проблемы рынка труда". 2024. № WP3/2024/01.
The history of economic thought knows a few of heated methodological controversies (Methodenstreit), the most famous of which was a “battle” at the end of the 19th century between Austrian and New historical schools on proper methods of social sciences. Later at the turn of the 1930–1940s a dispute arose between J.M. Keynes, on the one ...
Added: December 18, 2024
Региональная неоднородность экономики России и работа трансмиссионного механизма денежно-кредитной политики
Zvereva V., / Банк России. Серия 1 "Аналитические записки". 2024. № 10.
Россия относится к числу стран, которым присуща выраженная региональная неоднородность. Эта неоднородность может быть связана с географическим расположением региона. Например, регионы Дальнего Востока имеют внешнеэкономические связи преимущественно со странами Азии, в то же время регионы запада России преимущественно связаны с Европой. Неоднородность также может быть следствием разной структуры экономик регионов. Например, в южных регионах традиционно ...
Added: December 12, 2024
Реакция банковских ставок на изменение ключевой ставки Банка России в условиях региональной неоднородности (оценки на панельных данных)
Zvereva V., Скуратова А. В., / Банк России. Серия 1 "Доклады об экономических исследованиях". 2024. № 129.
Целью данного исследования являлась оценка вклада федеральных и региональных факторов в работу процентного канала трансмиссионного механизма денежно-кредитной политики (ТМ ДКП) после начала пандемии COVID-19 в 2020 году и усиления санкционного давления в 2022 году. Полученные результаты свидетельствуют о том, что наблюдается заметная асимметрия и неоднородность в реакции региональных банковских ставок на ДКП в зависимости от рынка (корпоративное кредитование или депозиты населения), характера ДКП (сдерживающая или стимулирующая) и влияния региональных факторов. Лаг ДКП составляет: 2–3 месяца для рынка корпоративного кредитования и 3–4 месяца для рынка ...
Added: December 12, 2024
Снижение экспрессии гена ELOVL5 изменяет механизм ферроптоза в клетках рака молочной железы MDA-MB-231
Razumovskaya A., Кулагин Т. А., Fatkulin A. et al., Биотехнология 2024 Т. 40 № 6 С. 74–83
To date, breast cancer is the most common oncological pathology among the female population both in Russia and worldwide. Previously, our laboratory team identified a significant prognostic marker for breast cancer, namely the ELOVL5 gene, the expression level of which in couple with the IGFBP6 gene allowed to predict the probability of breast cancer recurrence ...
Added: November 11, 2024
A Systematic Review of the Use of Technology in Educational Assessment Practices: Lesson Learned and Direction for Future Studies
Retnawati H., Kardanova E., Sumaryanto ,. et al., INTERNATIONAL JOURNAL OF ROBOTICS AND CONTROL SYSTEMS 2024 Vol. 4 No. 4 P. 1656–1693
Previous studies have demonstrated that technology helps achieve learning outcomes. However, many studies focus on just one aspect of technology’s role in educational assessment practices, leaving a gap in studies that examine how various aspects affect the use of technology in assessments. Hence, through a systematic work, we analyzed the extent and manner in which technology is integrated into educational assessments and how education level, domain of ...
Added: October 10, 2024
IGFBP6 regulates extracellular vesicles formation via cholesterol abundance in MDA-MB-231 cells
Shkurnikov M., Darya Averinskaya, Stekolshchikova E. et al., Biochimie 2024 Vol. 227 P. 77–85
Breast cancer recurrence is associated with the growth of disseminated cancer cells that separate from the primary tumor before surgical treatment and hormonal therapy and form a metastatic niche in distant organs. We previously demonstrated that IGFBP6 expression is associated with the risk of early relapse of luminal breast cancer. Knockdown of IGFBP6 in MDA-MB-231 breast cancer ...
Added: August 14, 2024
Imidazole-4-N-acetamide Derivatives as a Novel Scaffold for Selective Targeting of Cyclin Dependent Kinases
Rusina P., Gandalipov E., Abdyusheva Y. et al., Cancers 2023 Vol. 15 No. 15 Article 3766
General toxicity for the organism is a major drawback of anticancer drugs. Development of new generation chemotherapeutics requires the knowledge about macromolecules critical for tumor cell viability. Among these species (called therapeutic targets), the protein kinases are the established enzymes. However, the parts of protein kinases that are supposed to be targeted by drugs can ...
Added: November 1, 2023
THE IMPACT OF FAMILY TIES AND FOUNDER INVOLVEMENT ON INNOVATION IN HIGH-TECH FIRMS
Хмелева П. А., Stepanova A. N., / Series WP BRP "Basic research program". 2022.
This paper investigates the impact of family participation and founder involvement in business on innovation in high-tech companies from the S&P500 index over the period 1999–2017. We demonstrate that the family firm paradox (family firms tend to invest less in innovation while remaining more efficient in innovation output) is not so obvious for technological companies. ...
Added: May 14, 2023
ELOVL5 and IGFBP6 genes modulate sensitivity of breast cancer cells to ferroptosis
Nikulin S., Razumovskaya A., Poloznikov A. et al., Frontiers in Molecular Biosciences 2023 Vol. 10 Article 1075704
Relapse of breast cancer is one of the key obstacles to successful treatment. Previously we have shown that low expression of ELOVL5 and IGFBP6 genes in breast cancer tissue corresponded to poor prognosis. ELOVL5 participates directly in the elongation of polyunsaturated fatty acids (PUFAs) that are considered to play an important role in cancer cell metabolism. Thus, in this work we ...
Added: February 22, 2023
A novel approach for a joint analysis of isomiR and mRNA expression data reveals features of isomiR targeting in breast cancer
Nersisyan S., Zhiyanov A., Еngibaryan N. et al., Frontiers in Genetics 2022 Vol. 13 Article 1070528
A widely used procedure for selecting significant miRNA-mRNA or isomiR-mRNA pairs out of predicted interactions involves calculating the correlation between expression levels of miRNAs/isomiRs and mRNAs in a series of samples. In this manuscript, we aimed to assess the validity of this procedure by comparing isomiR-mRNA correlation profiles in sets of sequence-based predicted target mRNAs ...
Added: December 1, 2022
One man’s pill is another man’s poison. Ambivalence of definitional power: the case of breast cancer drugs in Russia
Berdysheva E., , in: The Ambivalence of Power in the Twenty-First Century Economy: Cases from Russia and beyond.: L.: UCL Press, 2022. Ch. 13 P. 261–279.
Russian cancer policy is being shaped in line with the militaristic metaphor of pharmacological war against cancer with  the drug-bullets that are produced in Russia. This study examines the role of meaning making (definitional) power in the arrangement of political choice with regard to this policy. It is aimed at demonstrating that in contrast to ...
Added: October 31, 2022
Рандомисты: новая экономика развития
Kapeliushnikov R., / Высшая школа экономики. Серия WP3 "Проблемы рынка труда". 2022. № WP3/2022/07.
The paper explores a curious phenomenon in the modern economic science — the intellectual confrontation between proponents of the “new” development economics (“randomistas”) and its opponents. The general message of the new approach is that the technique of randomized controlled experiments (RCT) should be considered the only truly scientific method and only this technique should be ...
Added: October 26, 2022
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