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Regular version of the site

Book chapter

SEARCHING FOR NON-B-DNA STRUCTURES AS NUCLEOSOME BARRIERS WITH MACHINE LEARNING METHODS

P. 363-364.
Tevanyan E., Poptsova M.

We trained Random Forest model to recognize patterns of nucleosome and non-B DNA structures, considered as potential nucleosome barriers in the mouse genome. We showed that among four types of structures – Z-DNA, H-DNA, G-Quadruplexes and SIDD regions – recognition of G-Quadruplexes and H-DNA showed the best performance.