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July 13, 2026
Biologists Discover Unique Properties of MiR-93-5p MicroRNA in Prostate Cancer
Researchers at the International Laboratory of Microphysiological Systems of the HSE Faculty of Biology and Biotechnology investigated how different isoforms of the same microRNA influence gene function in prostate adenocarcinoma. The study found that in some cases, microRNAs can reinforce each other’s effects by targeting and suppressing the same genes. This finding offers a fresh perspective on the molecular mechanisms underlying tumour development and on the search for disease biomarkers. The results have been published in PeerJ.
July 13, 2026
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Mikhail Samatov focuses on the theoretical study of perovskite solar cells. In this interview for the HSE Young Scientists project, he talks about working on HSE University’s supercomputer, collaborating with Peking University, and making furniture.
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Web application for motor rehabilitation after stroke based on neuroeconomic approaches

European Stroke Journal. 2021. Vol. 6. No. 1S. P. 512–513.
Novikov P., Panidi K., Germanova K., Nikulin V., Nazarova M.

Background and Aims:Learned non-use is a substantial problem for neurorehabilitation and it represents the difference between the functional capacity of an affected limb (e.g. based on the Fugl-Mayer scale) and the actual use of this limb in a daily life (e.g. using AAUT scale). Although the Constraint-Induced Therapy has proved its effectiveness, this approach has some methodological limitations, and it does not always guarantee active use of the affected limb after discharge from clinical premises. Regardless of an introduction of the International Classification of Functioning (ICF), which aims to integrate biological, psychological, and social factors for effective individualized rehabilitation protocols, rehabilitation is still on its way to becoming an ecological intervention. Nowadays, researchers are actively investigating possible directions towards making rehabilitation more patient-oriented, hence stimulating active participation in the treatment procedures. Methods: We developed a web application for stroke patients to investigate their motor decision making. The software is developed using the Blazor web framework. It allows to trace hand movements using the touch screen. Results: Web application is available by https://risk-n-reach. azurewebsites.net/. Two aims, sure and risky, are available for reaching by subject’s hand during each trial. Baseline stage consists of determining the probabilities of reaching a ‘risky’ aim at its different positions on a screen. After baseline stage it’s possible to suggest scores dependent on a ‘risky’ aim position. Conclusions: We expect that investigation of neuroeconomic parameters of motor decision making will be a step forward, which will help to overcome the learned non-use problem in stroke patients.

Research target: Basic Medicine Medical Technologies Biology Computer Science Psychology
Language: English
DOI
Keywords: web applicationneuroeconomicsmotor cortexstroke rehabilitationSoftwareupper limb
Publication based on the results of:
Fundamental study of the mechanisms of brain activity in the performance of cognitive and neuroeconomic tasks in health and disease using psychophysiological, neuroanatomical, neurocomputational and behavioral approaches (2021)
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