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Article

Адаптация и валидизация вопросника для оценки риска систематических ошибок в рандомизированных контролируемых испытаниях

Реброва О. Ю., Федяева В. К., Хачатрян Г. Р.

The questionnaire of the Cochrane Collaboration developed to assess risks of the main bias in randomized controlled trials (RCT) was translated into Russian. It was also adapted and validated. We proposed to consider the risk of the conflict of interests as a mandatory part of the questionnaire. Also we slightly modified the rule to determine the total risk of bias in RCTs. Validation of the questionnaire accomplished by two experts on 20 RCTs demonstrated good agreement: Kappa = 0.785, 95% CI (0.503; 1.000)