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Biomarkers of Obsessive-Compulsive Disorder Subtypes: A Literature Review
International Journal of Molecular Sciences. 2025. Vol. 26. No. 17. Article 8578.
Proshina E., Anastasia Gaidareva, Margarita Beskhizhko, Kazaryan G., Bainbridge E., Khayrullina G.
Obsessive–compulsive disorder (OCD) is a heterogeneous mental illness characterized by a variety of clinical manifestations and underlying neurobiological mechanisms. Modern research highlights the importance of identifying subtypes of OCD—separate categories that are characterized by specific phenotypic manifestations. This review provides a systematic integration of multi-level biomarker data (genetic, neuroimaging, neuropsychological) specifically aligned with the most consistently replicated, symptom-based subtypes of OCD. Our findings demonstrate that distinct OCD subtypes are underpinned by divergent neurobiological pathways, involving dysregulation across glutamatergic, serotonergic, dopaminergic, and neurotrophic systems, as well as distinct patterns of brain region engagement. The most extensive body of evidence currently exists for the contamination/cleaning and symmetry/ordering OCD subtypes. In contrast, other subtypes require more rigorous investigation. The findings from this study can provide theoretical prerequisites for future experimental studies involving larger cohorts of OCD patients, who can then be classified based on their detected biomarkers and tested accordingly.
Medushevsky A. N., Liberal.ru 2026
The Liberal Mission Foundation continues to introduce readers to new concepts of democracy and relevant publications. This discussion focuses on the challenges facing democracy in the era of globalization, as addressed in two recent books: *The Backsliders: Why Leaders Undermine Their Own Democracies* by S.C. Stokes (2025) and *Critical Theories and the Postsocialist Challenge: Race, ...
Added: August 26, 2026
Medushevsky A. N., Вопросы теоретической экономики 2026 № 2 С. 146–164
It is generally accepted that the basis of social and legal stability in any society is a consensus on vir tue — the fundamental values of proper behavior, ways of maintaining and reproducing them. And, conversely, the destruction of this consensus is a sign of the loss of stability and divergence of positions of social ...
Added: August 26, 2026
Кубкин Я. В., Российский кардиологический журнал 2026 Т. 31 № 8S
Goal. To assess the contribution of polygenic risk scores to the short‑term mortality prediction model in patients with dilated cardiomyopathy (DCM).
Materials and methods. The study included 137 patients with DCM. The mean age was 56.8 ± 13.5 years; there were 115 men (83.9 %). The median follow‑up period was 17 [13; 22] months. During the follow‑up period, 26 ...
Added: August 24, 2026
Vlasenko D., Saranskaia I., Zakharov D., European Physical Journal: Special Topics 2026 P. 1–16
Hypergraphs provide a natural framework for representing neurophysiological interactions distributed across sets of sensors. A key methodological question is how hyperedges should be defined from frequency-resolved electroencephalography/magnetoencephalography (EEG/MEG) data. We demonstrate a construction strategy in which hyperedges are obtained from canonical coherence (caCOH), an extension of coherence that estimates coupling between multidimensional signal spaces. To ...
Added: August 18, 2026
Diachkova M., Lelik V., Dorofeeva S. et al., Language Resources and Evaluation 2026 Vol. 60 Article 68
This article presents the Russian Language-Monolingual corpus (RusLan-M, v.1.0), a longitudinal multimedia collection of early child speech from two Russian-speaking monolingual children: Tosya (ages 0;10–3;10, 246 recordings) and Yasha (ages 1;04–3;00, 42 recordings). The corpus consists of approximately 41 h (2,454 min.) of video recordings and 35,386 child utterances, available with transcriptions in the CHAT ...
Added: August 17, 2026
Badarin A., Ratnikov F., Andreev A., European Physical Journal: Special Topics 2026 P. 1–10
EEG recordings are often affected by the loss or corruption of individual channels due to electrode detachment, poor scalp contact, or external interference. Such channels must be accurately reconstructed before further analysis. In this study, we investigate Next-Generation Reservoir Computing (NG-RC) as a data-driven approach for reconstructing corrupted EEG channels and compare its performance with ...
Added: August 12, 2026
Lucas J., Hebbar P., Ryabov F. et al., / Series 10.64898/2026.07.21.739710 "10.64898/2026.07.21.739710". 2026.
A pangenome reference overcomes the inherent limitation of any individual reference genome by integrating the variation present in a population. We present the Human Pangenome Reference Consortium’s (HPRC) Release 2 (HPRC2), an openly available, second phase pangenome that is an approximately fivefold expansion in genome number over HPRC Release 1 (HPRC1) and measurable improvement in ...
Added: August 10, 2026
Sandlerskiy R., Elsevier, 2026.
Encyclopedia of Ecology, Third Edition, Four Volume Set - with over 300 chapters - once again provides a comprehensive reference work covering the current ideas and practices in ecology.
Ecology is the ideal field for studying complex, adaptive, and self-organizing systems and by observing and understanding ecosystems, it provides valuable insights into creating sustainable systems. This knowledge is ...
Added: August 9, 2026
Dadinova L., Petoukhov M., Mozhaev A. et al., Crystallography Reports 2026 Vol. 71 P. 52–58
Bacterial chromosomes are tightly packed in the cells due to interactions with specific nucleoid-associated proteins. Among them, the IHF protein draws attention due to its presumed influence on intracellular crystallization processes, leading to bacterial resistance to drugs. The crystal structure of the IHF heterodimer is known only in complex with a short DNA fragment, whereas ...
Added: August 6, 2026
Vasilieva E., Trifonova A., Bultseva M. A., Current Psychology 2026 Vol. 45 Article 1320
The current exploratory study aims to reveal identity gaps and interpersonal communication strategies used by Russians to overcome social identity crises. Based on previous research, we assume that many Russians who live both in Russia and abroad face ethnic and national identity threats and experience different social identity crises due to recent geopolitical events. This ...
Added: August 6, 2026
Ulgen H., Journal of International Students 2026 Vol. 16 No. 17 P. 283–312
This study reports a secondary analysis of phenomenologically informed, semistructured interviews with 15 Turkish undergraduate and graduate students at three universities in Moscow and examines how peer networks function beyond emotional buffering to support academic engagement and institutional navigation in Russian–medium higher education. Drawing on social support theory, communities of practice, and community cultural wealth ...
Added: August 5, 2026
A. Radygina, S. Kulikova, Herald of the Russian Academy of Sciences 2025 Vol. 95 No. 6 P. 963–970
Musical training has a significant impact on brain organization, leading to functional and structural
adaptations that enhance auditory, visual, motor, and cognitive processes. This study investigates how
extensive musical training shapes functional brain connectivity by comparing professional musicians and
non-musicians. Using EEG phase-locking value (PLV) analysis, we examined neural synchronization across
alpha, beta, and gamma frequency ranges during music ...
Added: August 5, 2026
Zolotareva A., Социальные науки и детство 2026 Т. 7 № 2 С. 66–77
Context and relevance. Early detection of anxiety and depression symptoms is a priority task for the child and adolescent mental health system. As Russian practice traditionally relies on separate instruments, assessing anxiety and depression in isolation, there is a need for integrated instruments. Objective. To examine the factor structure of the Russian version of the ...
Added: August 4, 2026
Iskakova B., Kleinlein E. V., Prisyazhniuk D. et al., European Journal of Education 2026 Vol. 61 No. 3 Article e70810
This study examines pre-service teachers' (PSTs) attitudes towards inclusive education in Germany and Russia and investigates how they relate to teacher training curricula and teacher educators' discourse. A mixed-methods design was used, including an online survey of PSTs (n = 460) with an open-ended question, curriculum review and exploratory interviews with university educators in both contexts. The ...
Added: August 3, 2026
Andresyuk E., Porozova N., Londaridze G. D. et al., Frontiers in Oncology 2026 Vol. 16 Article 1875861
Inhibition of the PD-1/PD-L1 axis has become a clinical standard across multiple malignancies, yet durable benefit remains restricted to selected settings, and many biologically rational combinations fail to maintain clinical benefit in late-phase evaluation. This structured, registry-derived narrative review, supported by expert-guided interpretation, was designed to identify the most clinically meaningful development directions among strategies ...
Added: July 31, 2026
Silina M., Dzhalilova D., Fokichev N. et al., Frontiers in Molecular Biosciences 2025 Vol. 12 Article 1674608
Humans and laboratory animals differ in their resistance to hypoxia, which affects the severity of inflammatory diseases and the rate of tumor progression. Therefore, it is necessary to search for methods for assessing the initial tolerance to oxygen deficiency and the risks of developing acute mountain sickness without direct hypoxia exposure on the organism. The ...
Added: March 24, 2026
Паникратова Я. Р., Пчелинцева М. Е., Егорова М. В. et al., Психиатрия, психотерапия и клиническая психология 2025 Т. 16 № 4 С. 528–543
Working memory (WM) may largely determine human cognitive capabilities and, consequently, daily functioning and performance in leading activity for diverse ages. Therefore, WM training seems to be relevant for both healthy individuals and patients with neurological or mental conditions of a broad age range. The kinds of WM training described in the literature are highly ...
Added: March 15, 2026
Isaev M., Pavel Bobrov, Olesya Mokienko et al., Sensors 2025 Vol. 25 No. 16 Article 5040
Understanding patterns of interhemispheric asymmetry is crucial for monitoring neuroplastic changes during post-stroke motor rehabilitation. However, conventional laterality indices often pose computational challenges when applied to functional near-infrared spectroscopy (fNIRS) data due to the bidirectional hemodynamic responses. In this study, we analyze fNIRS recordings from 15 post-stroke patients undergoing motor imagery brain-computer interface training across ...
Added: March 6, 2026
Portnova G., Proskurnina E., Liaukovich K. et al., Journal of Molecular Neuroscience 2026 Vol. 76 Article 19
This study investigates the relationship between stress coping ability, salivary antioxidant capacity (AOC), and trace element concentrations, focusing on zinc (Zn) and potassium (K). A cohort of 73 participants, divided into groups based on stress coping ability (SCA) (“adaptive”, “intermediate”, and “maladaptive”), underwent cognitive tasks while physiological and behavioral data were collected. Saliva samples were ...
Added: February 2, 2026
Petrova D., EBioMedicine 2024
Added: January 18, 2026
Petrova D., Biomolecules 2025
Added: January 18, 2026
Pechenkova E., Королькова О. А., Паникратова Я. Р. et al., В кн.: Когнитивная наука в Москве: новые исследования. Материалы конференции 25 – 26 июня 2025.: М.: Буки Веди, 2025. С. 394–399.
Working memory (WM) is a system for the short-term storage and processing of a limited amount of information required for a current cognitive activity. WM largely determines a person's cognitive abilities throughout life and has been shown to decline with aging. This decline affects WM updating to a greater degree than maintenance and is more ...
Added: December 29, 2025
Грищенко Д. И., Falikman M., Pechenkova E. et al., В кн.: Когнитивная наука в Москве: новые исследования. Материалы конференции 25 – 26 июня 2025.: М.: Буки Веди, 2025. С. 153–157.
The human gaze is a significant source of information during social interactions, and as such, it has been the focus of intensive study by researchers from various scientific disciplines for many decades. Two types of social gaze that develop sequentially in phylogeny and ontogeny are gaze following and mutual gaze. Previous behavioral research has identified ...
Added: December 29, 2025
Schoenmaekers C., Jillings S., Mortaheb S. et al., NPJ MICROGRAVITY 2025 Vol. 11 Article 71
Long-duration spaceflight affects otolith-mediated ocular counter-roll (OCR) and brain function, but the relationship between these changes is unclear. This study examines whether OCR changes correlate with functional connectivity (FC) changes in the vestibular network in the same cosmonauts after a long-duration (6-month) spaceflight mission. Using a human vestibular atlas, we found that changes in FC ...
Added: December 28, 2025