Are subjective language complaints in memory clinic patients informative?

Aging, Neuropsychology, and Cognition. 2024. Vol. 31. No. 5. P. 795–822.

Malyutina S., Alina Zabolotskaia, Savilov V., Syunyakov T., Kurmyshev M., Kurmysheva E., Irina Lobanova, Osipova N., Karpenko O., Andriushchenko A.

To diagnose mild cognitive impairment, it is crucial to understand whether subjective cognitive complaints reflect objective cognitive deficits. This question has mostly been investigated in the memory domain, with mixed results. Our study was one of the first to address it for language. Participants were 55-to-93-year-old memory clinic patients (n = 163). They filled in a questionnaire about subjective language and memory complaints and performed two language tasks (naming-by-definition and sentence comprehension). Greater language complaints were associated with two language measures, thus showing a moderate value in predicting language performance. Greater relative severity of language versus memory complaints was a better predictor, associated with three language performance measures. Surprisingly, greater memory complaints were associated with better naming, probably due to anosognosia in further disease progression or personality-related factors. Our findings highlight the importance of relative complaint severity across domains and, clinically, call for developing self-assessment questionnaires asking specific questions about multiple cognitive functions.

Keywords: пожилые люди, грамматический анализ, language processing, лексический доступ, Lexical retrieval, aging, grammatical processing, возрастные изменения, age-related changes, mild cognitive impairment, subjective cognitive complaints, мягкое когнитивное снижение, речевая функция, субъективные когнитивные жалобы

Publication based on the results of: A Multidisciplinary Study of the Human Brain: Behavioral, Psychophysiological and Mathematical Approaches to Cognitive Functioning (2024)