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Updated Understanding of the Degenerative Disc Diseases - Causes Versus Effects - Treatments, Studies and Hypothesis
Current Genomics. 2020. Vol. 21. No. 6. P. 464–477.
Muresanu C., Somasundaram S., Neganova M., Bovina E., Vissarionov S., Ofodile O. ., Fisenko V., Bragin V., Minyaeva N. N., Chubarev V., Klochkov S., Tarasov V., Kirkland C., Aliev G.
Background: In this review we survey medical treatments and research strategies, and we discuss why they have failed to cure degenerative disc diseases or even slow down the degenerative process.
Objective: We seek to stimulate discussion with respect to changing the medical paradigm associated with treatments and research applied to degenerative disc diseases.
Method Proposal: We summarize a Biological Transformation therapy for curing chronic inflammations and degenerative disc diseases, as was previously described in the book Biological Transformations controlled by the Mind Volume 1.
Preliminary Studies: A single-patient case study is presented that documents complete recovery from an advanced lumbar bilateral discopathy and long-term hypertrophic chronic rhinitis by application of the method proposed.
Conclusion: Biological transformations controlled by the mind can be applied by men and women in order to improve their quality of life and cure degenerative disc diseases and chronic inflammations illnesses.
Priority areas:
engineering science
Language:
English
Салагай О. О., Сахарова Г. М., Антонов Н. С. et al., Здоровье населения и среда обитания 2026 Т. 34 № 6 С. 7-17
Introduction: Tobacco and nicotine use is a risk factor for noncommunicable diseases, malignant neoplasms, and a severe course of infectious diseases. This factor, however, is manageable and can be modified through prevention programs allowing for trends and specifics of the use of tobacco and nicotine products.
Objective: To analyze patterns of tobacco and nicotine product use among the ...
Added: September 15, 2026
Салагай О. О., Сахарова Г. М., Антонов Н. С. et al., Медицинский вестник Юга России 2026 Т. 17 № 2 С. 109–119
Objective: analysis of the structure and characteristics of the consumption of various types of tobacco and nicotine-containing products by Veterans.
Materials and methods: the analysis was carried out based on the results of a survey of Veterans using a developed questionnaire. The survey was conducted at the offices of the Defenders of the Fatherland Foundation. The proportions ...
Added: September 15, 2026
Dimertsev A. V., Batmanova Y. V., Zhikhar T. V. et al., Burdenko's Journal of Neurosurgery, Россия 2025 Vol. 6 P. 38–45
Background. There are some unresolved issues in surgery for gliomas of Broca’s area (optimal intraoperative testing, cortical mapping, and stimulation parameters).
Objective. To clarify the peculiarities of neurosurgical technique and speech testing in surgery for gliomas of Broca’s area.
Material and methods. A single-center cohort retrospective study was devoted to surgical treatment of patients with Broca’s area ...
Added: September 14, 2026
Zheltyakova M., Korotkov A., Bursov K. et al., Herald of the Russian Academy of Sciences 2026 Vol. 95 P. 1048–1057
The Reading the Mind in the Eyes Test (RMET) is a widely used tool for assessing affective mentalization in both clinical and research contexts. Although translated into many languages, no validated Russian-language version has been available. Furthermore, the limited number of stimuli in the original RMET constrains its applicability in neuroimaging studies. This study presents ...
Added: September 13, 2026
Kang J., Kim H. J., Kim M. S. et al., Nature Medicine 2026 No. 32 P. 527–544
Drug use disorders (DUDs) are emerging global public health challenges. Here we investigated the global and regional estimates of the prevalence and burden of DUDs, including amphetamine, cannabis, cocaine and opioid use disorders, from 1990 to 2023 for 204 countries and territories by using the Global Burden of Disease Study 2023. Overall, trends in global ...
Added: September 9, 2026
Ребрейкина А. Б., Liaukovich K., Современная зарубежная психология 2024 Т. 13 № 2 С. 33–43
Создание методик диагностики на основе анализа движений глаз является особенно актуальным для оценки когнитивных функций у детей, которые не могут дать речевой или моторный ответ в силу своего возраста или из-за нарушений развития. Для таких детей использование объективных методов оценки когнитивных функций на основе айтрекинга может стать полезным диагностическим инструментом, дополняющим традиционные поведенческие опросники и ...
Added: September 8, 2026
Ребрейкина А. Б., Liaukovich K., Современная зарубежная психология 2023 Т. 12 № 4 С. 51–61
Активное развитие метода видеоокулографии, т. е. регистрации движений глаз, создает возможности для создания новых подходов для развития когнитивных функций и обучения. Методики, основанные на видеоокулографии, могут быть полезны не только для детей с серьезными нарушениями моторных функций, но и детей с нарушениями развития когнитивных функций, прежде всего внимания, так как контроль движений глаз тесно связан ...
Added: September 8, 2026
Proskurnina E., Liaukovich K., Bychkovskaya L. et al., Metabolites 2023 Vol. 13 No. 1 P. 73
Added: September 7, 2026
Alshanskaia E., Portnova G., Liaukovich K. et al., Frontiers in Neuroscience 2024 Vol. 18
Added: September 7, 2026
Liaukovich K., Panfilova E., Khayrullina G. et al., International Journal of Psychophysiology 2025 Vol. 207 P. 112475
Added: September 5, 2026
Liaukovich K., Bainbridge E., Khayrullina G. et al., Neuroscience and Behavioral Physiology 2026 Vol. 56 P. 10–19
Added: September 5, 2026
Kashevarova O., Portnova G., Khayrullina G. et al., Frontiers in Psychiatry 2026 Vol. 17 P. 1776019
Added: September 5, 2026
Khodadoust J., Kulikova S., Khodadoust F., Biomedical Signal Processing and Control 2027 Vol. 129 P. 111284–111284
Acute ischemic stroke (AIS) analysis from two-dimensional (2D) clinical imaging is hindered by uncontrolled slice tilt and geometric inconsistencies that violate the assumptions of pose-agnostic deep learning (DL) models. This paper proposes a unified geometry-aware, frequency-domain framework for tilted slice localization and ischemic stroke segmentation that explicitly decouples pose estimation from lesion analysis. The method ...
Added: September 2, 2026
Daria Lukianenko, Ragimova A., Mukhorina A. et al., European Physical Journal: Special Topics 2026 P. 1–24
Electronic health records (EHRs) contain vast volumes of clinical information that encode complex relationships between diseases. Traditional approaches to the analysis of interrelated or co-occurring diseases have focused on pairwise associations between diagnoses, missing the higher-order structures that characterise multimorbid patients. The present paper offers a narrative review of existing statistical, machine-learning, and artificial intelligence ...
Added: August 20, 2026
Moshkin A., Fedorov M., Arlazarov V. et al., Algorithms 2026 Vol. 19 No. 7 Article 523
Artificial intelligence (AI) technologies, which are being actively developed in modern medicine today, increase the speed and quality of patient care. This article mainly seeks to demonstrate the use of various options of computer analysis of clinical images to solve practical problems of increasing the efficiency of routine diagnostics using retrospective analysis, as well as ...
Added: August 17, 2026
Dmitrova E., Буклина С. Б., Gronskaya N. E. et al., Вопросы нейрохирургии им. Н.Н. Бурденко 2026 Т. 90 № 4 С. 87–94
Effective intraoperative speech mapping requires specific test with standardized linguistic material. The last one should capture speech function supported by brain region targeted for resection. It is necessary to develop a test tailored to specific patient’s needs and document intraoperative linguistic support. The objective of this report was to describe the procedure of intraoperative speech testing and battery of intraoperative tests for Russian language. We correlated intraoperative tests with brain regions and speech functions, as well as presented an application ...
Added: August 12, 2026
Provlotskaya I., Minnigulova A., Gordeyeva E. et al., Brain Structure and Function 2026 Vol. 231 Article 113
The Wada test is an invasive procedure used to assess language and memory lateralization. Despite the widespread use of the Wada test in the population of people with epilepsy, the two existing standardized protocols for conducting the procedure are methodologically different and do not fully account for language comprehension as a separate domain. In this ...
Added: August 4, 2026
Elena A. Andresyuk, Natalya O. Porozova, Londaridze G. et al., Frontiers in Oncology 2026 Vol. 16 Article 1875861
Inhibition of the PD-1/PD-L1 axis has become a clinical standard across multiple malignancies, yet durable benefit remains restricted to selected settings, and many biologically rational combinations fail to maintain clinical benefit in late-phase evaluation. This structured, registry-derived narrative review, supported by expert-guided interpretation, was designed to identify the most clinically meaningful development directions among strategies ...
Added: July 31, 2026
Хайлова Ж. В., Омельяновский В. В., Терян Р. А. et al., Опухоли женской репродуктивной системы 2025 Т. 21 № 1 С. 86–105
Цель исследования – определить наиболее целесообразную стратегию скрининга и ранней диагностики рака шейки матки (РШМ) в Российской Федерации с точки зрения клинической (диагностической) и экономической эффективности.
Материалы и методы. Для оценки клинической (диагностической) эффективности различных стратегий скрининга проведен систематический обзор публикаций об исследованиях, оценивающих эффективность применения цитологического исследования и тестирования на вирус папилломы человека (ВПЧ) с целью диагностики ...
Added: July 16, 2026
Sun Z., Khvostikov A., Krylov A. et al., Machine Learning and Knowledge Extraction 2026 Vol. 8 No. 1 Article 8
Whole-slide histology images (WSIs) can exceed 100 k × 100 k pixels, making direct pixel-level segmentation infeasible and requiring patch-level classification as a practical alternative for downstream WSI segmentation. However, most approaches either treat patches independently, ignoring spatial and biological context, or rely on deep graph models prone to oversmoothing and loss of local tissue ...
Added: July 16, 2026
Turkina A., Vinogradova O., Lomaia E. et al., Annals of Hematology 2025 Vol. 104 P. 2707–2715
Vamotinib (PF-114) is a 3rd -generation, ATP-competitive oral tyrosine kinase inhibitor (TKI) active against wild-type and mutated BCR::ABL1 isoforms including BCR::ABL1T315I. We present final results of a phase-1 vamotinib dose-escalation study to identify maximum tolerated dose (MTD) and dose-limiting toxicity (DLT) followed by expansion cohorts. 51 subjects with chronic myeloid leukaemia (CML) failing ≥ 1 2nd generation TKI or with BCR::ABL1T315I were ...
Added: July 16, 2026
Гущина В. А., / Series chemrxiv-2023-vpzhz-v2 "ChemRxiv". 2023.
All-inorganic perovskite CsPbBr3 and Cs4PbBr6 nanoparticles are being intensively studied due to their unique properties and wide range of applications; however, however, the nature of their optical properties is not yet fully understood due to the difficulty of synthesis of singlephase nanoparticles. In this article we describe the features of the synthesis of single-phase particles ...
Added: May 14, 2026
Pilé I., Deng Y., Shchur L., / Series arXiv "math". 2026. No. 2604.10254.
We investigate the spatial overlap of successive spin configurations in Markov chain Monte Carlo simulations using the local Metropolis algorithm and the Svendsen-Wang and Wolff cluster algorithms. We examine the dynamics of these algorithms for two models in different universality classes: the Ising model and the Potts model with three components. The overlap of two ...
Added: April 20, 2026
Sun L., Jin L., Sun T. et al., IMETA 2026 Vol. 5 No. 1 Article e70108
Climate adaptation genomics of cattle. We comparatively analyzed genomic data from 85 Old World cattle breeds/populations of Eurasia and Africa to identify genetic factors associated with climate factors. Environmental genome-wide association studies revealed 3165 single-nucleotide polymorphisms (SNPs) with strong correlations between climate factors and allele frequencies. We also identified loci that were significantly associated with ...
Added: March 25, 2026