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Объединенная математическая модель роста первичной опухоли и первичных метастазов рака молочной железы (IV стадия РМЖ)
Гл. 5. С. 13–21.
Tyuryumina E., Neznanov A.
In press
In book
Соболевский А. Н. [б.и.], 2016.
Kazantseva A. V., A.V. Toropova, Khusnutdinova E. K. et al., ВАВИЛОВСКИЙ ЖУРНАЛ ГЕНЕТИКИ И СЕЛЕКЦИИ, Федеральный исследовательский центр Институт цитологии и генетики Сибирского отделения Российской академии наук» (ИЦиГ СО РАН) (Новосибирск) 2025 Vol. 30 No. 3 P. 470–481
The development of musical abilities, including absolute pitch, musical memory, rhythm sense, and musicality, at a high degree is determined by a hereditary component (up to 68 %). The studies implementing a genome-wide linkage and association approach to musical aptitude have revealed more than 100 genetic loci. This spectrum is comprised of the genes encoding ...
Added: May 29, 2026
Kuzmina L., Осипов Ю. В., Строительные материалы 2025 № 10 С. 83–87
Models of transport and filtration of small particles in porous media are used in the construction industry when designing foundations and underground structures. A liquid with particles moves through the channels of a porous soil. When particles are transported, some of them are locked in the pores and form a sediment. If the fluid flows ...
Added: February 25, 2026
Leonid Grinin, Markov A., Korotayev A., Journal of Big History 2025 Vol. 8 No. 3 P. 1–51
In this paper, Grinin et al. survey general similarities and differences between biological and social macroevolution and phases of Big History. The comparison of biological and social evolution is an important but (regrettably) understudied subject. The authors have endeavored to make a systematic comparison between biological and social evolution at different levels of analysis and ...
Added: November 1, 2025
Akhremenko A. S., Philippov I., Sychev V. et al., Политическая наука 2025 № 1 С. 77–102
Modern academic literature has focused on technology adaptation and innovation in politics and public administration. At present, there is a large number of studies, the central object of which is such an actively developing phenomenon as public digital services. Despite the diverse range of theoretical approaches, there is no established methodological tradition of modelling the ...
Added: May 1, 2025
Efremov Y., Ermolaeva A., Vladimirov G. et al., Plos One 2022 Vol. 17 No. 6
Cardiovascular diseases associated with high cholesterol (hypercholesterolemia) and low-density lipoproteins (LDL) levels are significant contributors to total mortality in developing and developed countries. Mathematical modeling of LDL metabolism is an important step in the development of drugs for hypercholesterolemia. The aim of this work was to develop and to analyze an integrated mathematical model of ...
Added: April 9, 2025
Silkina M., Razumovskaya A., Timur Kulagin et al., Biochimie 2025 Vol. 234 P. 48–61
Breast cancer remains a major challenge and new therapeutic approaches are needed for its treatment. Ferroptosis is considered a promising alternative cell death mechanism to eliminate resistant cancer cells. In previous works, we identified that lower IGFBP6 gene expression in tumor tissue corresponds to a worse prognosis for breast cancer patients and, at the same, time makes ...
Added: April 9, 2025
Romanova T. V., Khomenko A., Legal Issues in the Digital Age 2022 Vol. 3 No. 2 P. 90–115
The article deals with validation of an integrative attribution algorithm based on the analysis of the author’s idiostyle using methods of interpretative linguistics with ob jectification of the available data with the help of mathematical statistics. The algo rithm addresses the identification problem of the attribution. The choice of parameters describing the individual style of ...
Added: March 12, 2025
Лесин А. В., Исаев А. В., Тонконогов Б. П. et al., Тонкие химические технологии 2023 Т. 19 № 6 С. 485–496
Objectives. A quick cold start of emergency and auxiliary power units based on diesel engines should be possible at any time without
problems and in the shortest possible time. The condition of the engine oil is one of the most important factors influencing the smooth
start-up of power plants. During diesel engine operation, engine oil accumulates soot ...
Added: February 26, 2025
Ishbulatov Y., Kurbako A., Vahlaeva A. et al., European Physical Journal: Special Topics 2024 Vol. 233 P. 569–577
We propose a mathematical model of the human cardiovascular and respiratory systems. The cardiovascular segment of the model simulates the main heart rate, oscillating blood pressure, peripheral vascular resistance, and nonlinear dynamics of the autonomic control of circulation, namely α- and βsympathetic and parasympathetic control. The respiratory part includes central pattern generator, lungs, and a ...
Added: December 24, 2024
Razumovskaya A., Кулагин Т. А., Fatkulin A. et al., Биотехнология 2024 Т. 40 № 6 С. 74–83
To date, breast cancer is the most common oncological pathology among the female population both in Russia and worldwide. Previously, our laboratory team identified a significant prognostic marker for breast cancer, namely the ELOVL5 gene, the expression level of which in couple with the IGFBP6 gene allowed to predict the probability of breast cancer recurrence ...
Added: November 11, 2024
Nefedova Y., Меди@льманах 2023 № 6(119) С. 44–51
В статье предлагается новый подход к анализу социальных конфликтов в цифровой медиасреде на основе автоматизированных методов обработки текстовой информации. Медиасообщество рассматривается как система, имеющая вход и выход, и задача математической модели сводится к определению наличия конфликта в ответных сообщениях и его основных характеристик, таких как количество конфликтных тем, длительность их обсуждения, уровень агрессии, а также ...
Added: September 29, 2024
Panchenko S. V., Dli M. I., Chernovalova M. V. et al., CIS Iron and Steel Review 2022 Vol. 23 P. 119–124
Mathematical model for theoretical analysis of thermophysical processes of melt drops solidification is examined during their motion inside cooling gas, applying to granulation task. The heat exchange equations during granulation, taking into account convection, heat conductivity in solid phase and Stefan conditions on the boundary of phase transition, are presented. The relationships characterizing correlation of ...
Added: September 26, 2024
Shkurnikov M., Darya Averinskaya, Stekolshchikova E. et al., Biochimie 2024 Vol. 227 P. 77–85
Breast cancer recurrence is associated with the growth of disseminated cancer cells that separate from the primary tumor before surgical treatment and hormonal therapy and form a metastatic niche in distant organs. We previously demonstrated that IGFBP6 expression is associated with the risk of early relapse of luminal breast cancer. Knockdown of IGFBP6 in MDA-MB-231 breast cancer ...
Added: August 14, 2024
Akhremenko A. S., Полис. Политические исследования 2024 № 2 С. 118–134
The influence of Internet communication on “street” protest activity is the focus of this paper. In recent years, there has been some stagnation in this area of research: a shortage of breakthrough works that indicate new research directions or at least significantly strengthen the empirical foundation of already established hypotheses. The paradox is that when ...
Added: March 31, 2024
Vladimir Staroverov, Alexei Galatenko, Evgeny Knyazev et al., PeerJ 2024 Vol. 12 Article e16964
Within-host infection dynamics of Omicron dramatically differs from previous variants of SARS-CoV-2. However, little is still known about which parameters of virus-cell interplay contribute to the observed attenuated replication and pathogenicity of Omicron. Mathematical models, often expressed as systems of differential equations, are frequently employed to study the infection dynamics of various viruses. Adopting such ...
Added: March 20, 2024
Petrov A., Sergey Zheglov, Akhremenko A. S., , in: 16th International Conference Management of large-scale system development (MLSD).: IEEE, 2023. Ch. 1 P. 1–5.
The paper studies protest campaigns consisting of both days with protest activity and days without activity. A dynamical agent-based model has been constructed. Numerical experiments showed that repression reduces the surviving probability of the campaign, but moderate repression may increase the turnout for the campaigns that survive. ...
Added: March 7, 2024
Yanova M., Zhiyanov A., Antipenko I. et al., Доклады российской академии наук. Науки о жизни 2023 Т. 513 № 1 С. 581–585
Gemcitabine monophosphate (dFdCMP), one of the intracellular forms of phosphorylated gem- citabine, determines its antitumor activity. A pharmaco-molecular model for determining relative gemcit- abine monophosphate level based on the assessment of the activity of ENT1 and ENT2 channels as well as dCK and CDA enzymes in tumor tissue was developed. Relative gemcitabine monophosphate level is ...
Added: November 17, 2023
Yurii Averboukh, Mathematical Control and Related Fields 2023 Vol. 13 No. 3 P. 1109–1130
In the paper, we study the dependence of solutions of the continuous-time finite state mean field game on initial distribution of players. Our approach relies on the concept of value multifunction of the mean field game that is a mapping assigning to an initial time and an initial distribution a set of expected outcomes of ...
Added: September 1, 2023
Nikulin S., Razumovskaya A., Poloznikov A. et al., Frontiers in Molecular Biosciences 2023 Vol. 10 Article 1075704
Relapse of breast cancer is one of the key obstacles to successful treatment. Previously we have shown that low expression of ELOVL5 and IGFBP6 genes in breast cancer tissue corresponded to poor prognosis. ELOVL5 participates directly in the elongation of polyunsaturated fatty acids (PUFAs) that are considered to play an important role in cancer cell metabolism. Thus, in this work we ...
Added: February 22, 2023