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October 8, 2026
HSE Experts Take Part in 23rd Annual Meeting of Valdai Discussion Club
The 23rd Annual Meeting of the Valdai Discussion Club was held from September 28 to October 1, 2026 under the theme ‘Responsibility for the Future: Limits of the Possible, or Limitless Possibilities?’ The forum brought together 120 experts from 40 countries, including representatives of China, the United States, India, Brazil, the United Kingdom, Germany, Egypt, Iran, and Japan.
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The HSE International Centre of Decision Choice and Analysis studies a wide range of methods for analysing decision-making and possible scenarios for the development of natural, socio-economic, and political phenomena using various mathematical models. The application of advanced mathematical methods to forecasting helps to prevent negative outcomes and avoid erroneous decisions. The HSE News Service spoke to the centre’s director, Prof. Fuad Aleskerov, about its work.
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The International N5 Symposium ‘Neural Networks and Nonlinearity in Nizhny Novgorod’ was held at the Nizhny Novgorod House of Scientists from September 23 to 26. The event was organised by HSE University–Nizhny Novgorod and the Nizhny Novgorod House of Scientists, with the participation of Sberbank and the Institute of Physics Belgrade. The symposium was held for the second time: the first conference took place in 2025 and attracted considerable interest from the academic community.

 

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Simulating the differences in directional cardiorespiratory coupling in the awake state and different stages of sleep using a comprehensive mathematical model

European Physical Journal: Special Topics. 2024. Vol. 233. P. 569–577.
Ishbulatov Y., Kurbako A., Vahlaeva A., Prokhorov M., Gridnev V., Karavaev A., Penzel T.

We propose a mathematical model of the human cardiovascular and respiratory systems. The cardiovascular segment of the model simulates the main heart rate, oscillating blood pressure, peripheral vascular resistance, and nonlinear dynamics of the autonomic control of circulation, namely α- and βsympathetic and parasympathetic control. The respiratory part includes central pattern generator, lungs, and a control loop sensitive to the concentration of CO2 and O2 in the arterial blood. Both parts of the model are linked in a physiological manner. The adequacy of the model is demonstrated by comparing the simulated time series to the experimental records of healthy subjects from the SIESTA database using spectral analysis, statistical analysis, and nonlinear measures of directional coupling. The proposed model can become a useful tool for investigation of the cardiovascular dynamics during sleep.

Research target: Mathematics
Language: English
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Keywords: mathematical modelsleepcardiovascular system
Publication based on the results of:
Математическое и радиофизическое моделирование сложной динамики живых систем для развития методов анализа экспериментальных данных (2025)
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