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News
August 25, 2026
Scientists Develop Algorithm for More Reliable Processors in Data Centres
Researchers from HSE MIEM and Samara University have developed the LRF-3D algorithm to automatically bypass idle nodes in three-dimensional networks-on-chip. Thanks to its hierarchical architecture, the algorithm outperforms existing solutions in both speed and path accuracy, improving processor reliability for use in data centres, supercomputers, and AI computing. The source code and test results are publicly available.
August 24, 2026
Researchers Develop Method for Direct Generation of Regulatory DNA
Researchers at HSE University have developed a model for generating promoters and enhancers—DNA sequences that regulate gene activity. The model works directly with DNA nucleotides, without first transforming them into a continuous numerical representation. This solution could be useful for applications in synthetic biology and gene therapy. The study results were presented at the ICLR 2026 Workshop ‘Generative AI in Genomics (Gen^2): Barriers and Frontiers.’
August 21, 2026
Social Integration: At the Crossroads of Knowledge and Values
The International Laboratory for Social Integration Research (ILSIR) at HSE University studies the challenges faced by vulnerable groups and explores ways to help them participate fully in everyday life. To develop effective solutions, the laboratory’s researchers combine cutting-edge methods with practical fieldwork. In this interview with the HSE News Service, Laboratory Head Elena Iarskaia-Smirnova discusses the laboratory’s work.

 

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Интеграция лабораторных и больничных информационных систем

Здравоохранение. 2005. № 2. С. 183–188.
Берсенева Е. А.
Research target: Basic Medicine Health Studies
Priority areas: business informatics
Language: Russian
Keywords: информационные технологии в здравоохранении
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Benchmarking Synolitic Graphs for Autism Classification from Multisite Resting-State fMRI
Zaikin A., Vlasenko D., Zakharov D. et al., Diagnostics 2026 Vol. 16 No. 17 P. 1–15
Background/Objectives: Synolitic graphs (SGs) were developed for task-based fMRI, where edge weights encode the discriminative power of pairwise regional features; whether similar information can be recovered from resting-state data was untested. We benchmarked SGs for autism spectrum disorder (ASD) classification using the multisite ABIDE-I dataset (871 subjects: 403 subjects with ASD, 468 typical controls; 17 sites; CC200 atlas). Methods: Using ...
Added: August 27, 2026
Measuring the composition and availability of human resources for health by sex in 204 countries and territories, 1990–2023, and workforce gaps for universal health coverage: a systematic analysis for the Global Burden of Disease Study 2023
Vlassov V., The Lancet Public Health 2026 Vol. 11 No. 9 P. e604–e629
Background Understanding the size, gender composition, and cadre mix of the health workforce and how it has evolved across time and locations can inform policies for planning, recruitment, training, and retention of human resources for health (HRH), and improvement of access to the health-care workforce among populations. Using comparable and standardised data sources, we aim to ...
Added: August 25, 2026
Localization in Medical Imaging: A Unified AI Approach for Ovaries, Follicles, and Vertebral Arteries
Moshkin A., Fedorov M., Arlazarov V. et al., Algorithms 2026 Vol. 19 No. 7 Article 523
Artificial intelligence (AI) technologies, which are being actively developed in modern medicine today, increase the speed and quality of patient care. This article mainly seeks to demonstrate the use of various options of computer analysis of clinical images to solve practical problems of increasing the efficiency of routine diagnostics using retrospective analysis, as well as ...
Added: August 17, 2026
Assessing walkability and climate adaptive capacity in relation to urban morphology and historical development
Shartova N., Mironova E., Geo Journal 2026 Vol. 91 Article 78
The historical timeline of urban development profoundly shapes the contemporary form and functionality of cities. Traditionally, cities were planned with limited consideration for the promotion of a healthy urban environment. Using Nizhny Novgorod, Russia, a city that has evolved from a medieval market town to an industrial centre and later into a multifunctional city with ...
Added: August 9, 2026
Global Burden of Elevated LDL-C: Findings From the Global Burden of Disease Study 2023
Vlassov V., JAMA - Journal of the American Medical Association 2026 Vol. 336 No. 8 P. 673–696
Importance  Elevated low-density lipoprotein cholesterol (LDL-C) is a modifiable risk factor for cardiovascular disease, the leading cause of premature death worldwide. Assessing the LDL-C–related burden is critical for guiding prevention and treatment strategies. Objectives  To estimate the global, regional, and national burden of ischemic heart disease and ischemic stroke attributable to elevated LDL-C (relative to 35-54 mg/dL) from ...
Added: August 4, 2026
Late-phase strategies to overcome limitations of PD-1/PD-L1 therapy: a clinical development trajectory through 2030
Andresyuk E., Porozova N., Londaridze G. D. et al., Frontiers in Oncology 2026 Vol. 16 Article 1875861
Inhibition of the PD-1/PD-L1 axis has become a clinical standard across multiple malignancies, yet durable benefit remains restricted to selected settings, and many biologically rational combinations fail to maintain clinical benefit in late-phase evaluation. This structured, registry-derived narrative review, supported by expert-guided interpretation, was designed to identify the most clinically meaningful development directions among strategies ...
Added: July 31, 2026
Reach: Recognising episodes of acute complexity in health: a predictive older patient prioritisation machine learning model
Maghsoohi A., Pavlov V., Rouse P. et al., Health Care Management Science 2026 Vol. 29 Article 37
As the numbers of older people (65 +) rise globally, the pressure on acute hospitals to provide efficient and effective care while addressing resource inequities increases. In this study we introduce Recognising Episodes of Acute Complexity in Health (REACH), a novel Automatic Machine Learning (AutoML)-based predictive model that prioritises older patients and assigns them to complex ...
Added: July 30, 2026
Global, regional, and national burden of road injuries 1990–2023: a systematic analysis for the Global Burden of Disease Study 2023
Vlassov V., The Lancet Public Health 2026 Vol. 11 No. 9 P. e589–e603
Background Road injuries are a leading cause of mortality and morbidity worldwide. Years of international efforts have aimed to strengthen policy engagement, including the 2020 UN General Assembly's proclamation of the Second Decade of Action for Road Safety (2021–30), targeting a 50% reduction in road traffic deaths and serious injuries by 2030. The aim of this ...
Added: July 25, 2026
Система здравоохранения России: что можно изменить уже сегодня. Идеи и предложения. 2-е издание, переработанное и дополненное
Авксентьева М. В., Ашихмин Я. И., Ашихмина О. В. et al., М.: ФГБУ "Издательство "Наука", 2023.
Предложены основные направления совершенствования планирования, организации и оплаты медицинской помощи, лекарственного обеспечения, информатизации и оценки технологий здравоохранения. Рекомендованы такие мероприятия, как конкретизация программы государственных гарантий бесплатного оказания гражданам медицинской помощи, создание системы общедоступного лекарственного обеспечения, использование клинико-статистических групп для оплаты медицинской помощи при ряде хронических неинфекционных заболеваний в амбулаторных условиях, формирование механизма привлечения соплатежей при ...
Added: July 16, 2026
Клиническая и экономическая оценка эффективности современных стратегий скрининга и ранней диагностики рака шейки матки в Российской Федерации
Хайлова Ж. В., Омельяновский В. В., Терян Р. А. et al., Опухоли женской репродуктивной системы 2025 Т. 21 № 1 С. 86–105
Цель исследования – определить наиболее целесообразную стратегию скрининга и ранней диагностики рака шейки матки (РШМ) в Российской Федерации с точки зрения клинической (диагностической) и экономической эффективности. Материалы и методы. Для оценки клинической (диагностической) эффективности различных стратегий скрининга проведен систематический обзор публикаций об исследованиях, оценивающих эффективность применения цитологического исследования и тестирования на вирус папилломы человека (ВПЧ) с целью диагностики ...
Added: July 16, 2026
Телемедицинские консультации в детской онкологии – гематологии: современный взгляд на актуальность, проблемы и их решения при оказании профильной медицинской помощи
Иванова А. А., Коган С. А., Горбунова Т. В. et al., Менеджер здравоохранения 2026 № 3 С. 96–105
The research r elev anc e is determined by the demand for telemedicine consultations (TMC) as one of health care digitalization pathways in Russian Federation. Telemedicine, regardless of the field, continues to prove its significant role, saving health resources without losing medical care quality. The TMC is regulated by federal level framework. Each year the ...
Added: July 16, 2026
WSI-GT: Pseudo-Label Guided Graph Transformer for Whole-Slide Histology
Sun Z., Khvostikov A., Krylov A. et al., Machine Learning and Knowledge Extraction 2026 Vol. 8 No. 1 Article 8
Whole-slide histology images (WSIs) can exceed 100 k × 100 k pixels, making direct pixel-level segmentation infeasible and requiring patch-level classification as a practical alternative for downstream WSI segmentation. However, most approaches either treat patches independently, ignoring spatial and biological context, or rely on deep graph models prone to oversmoothing and loss of local tissue ...
Added: July 16, 2026
Оценка социальных эффектов от внедрения системы организационных мероприятий для совершенствования оказания медицинской помощи при онкологических заболеваниях на региональном уровне в субъектах Центрального федерального округа
Хайлова Ж. В., Омельяновский В. В., Михайлов И. А. et al., Менеджер здравоохранения 2026 № 4 С. 41–52
The urgency of the problem of organizing effective medical care for cancer patients is determined by the steady trend of increasing incidence of malignant neoplasms, the high proportion of this pathology in the structure of overall mortality, as well as significant medical, demographic and socio-economic losses for society.Purpose of the st udy is to conduct ...
Added: July 16, 2026
Социологическое исследование влияния комплекса организационных мероприятий по внедрению инновационных медицинских технологий в многопрофильном стационаре на качество жизни пациентов
Габриелян А. Р., Александрова О. Ю., Михайлов И. А., Здоровье мегаполиса 2026 Т. 7 № 2 С. 7–16
Objective. To evaluate the impact of a series of organizational measures for implementing innovative medical technology in a multidisciplinary hospital on patient quality of life based on patient self-assessments. Results. Patients who received care using innovative medical technology within a systemic organizational approach demonstrated a significantly higher level of overall satisfaction with the quality of care. ...
Added: July 16, 2026
Международные подходы к оценке сложности труда специалистов с высшим медицинским образованием (врачей) разных специальностей
Ахапкина Е. С., Омельяновский В. В., Тулупова О. Н. et al., Медицинские технологии. Оценка и выбор 2026 Т. 48 № 2 С. 70–77
OBJECTIVE To analyze international approaches to assessing the labor complexity for different specialists with higher medical education (physicians). MATERIAL AND METHODS We performed a systematic searching and content analysis of foreign and national studies and documents devoted to labor complexity of different specialists with higher medical education (doctors). A group of experts among the authors of this study discussed and identified significant factors in assessing complexity. RESULTS There are 2 main systems to assess physician workload complexity in foreign countries. The first approach is based ...
Added: July 16, 2026
Phase-1 study of vamotinib (PF-114), a 3rd generation BCR::ABL1 tyrosine kinase-inhibitor, in chronic myeloid leukaemia
Turkina A., Vinogradova O., Lomaia E. et al., Annals of Hematology 2025 Vol. 104 P. 2707–2715
Vamotinib (PF-114) is a 3rd -generation, ATP-competitive oral tyrosine kinase inhibitor (TKI) active against wild-type and mutated BCR::ABL1 isoforms including BCR::ABL1T315I. We present final results of a phase-1 vamotinib dose-escalation study to identify maximum tolerated dose (MTD) and dose-limiting toxicity (DLT) followed by expansion cohorts. 51 subjects with chronic myeloid leukaemia (CML) failing ≥ 1 2nd generation TKI or with BCR::ABL1T315I were ...
Added: July 16, 2026
Shared environment, shared mechanisms: comparing pathways to mental health outcomes among indigenous youth and youth with other ethnic backgrounds
Arina Bukina, Eritsyan K., Antonova N. et al., Frontiers in Psychology 2026 Vol. 17 Article 1824428
Background:  Numerous studies have shown that indigenous populations experience poorer health outcomes compared to people with other backgrounds. However, the interpretation of these disparities remains challenging due to differences in living conditions and social environments, as well as by potential measurement-related biases. Little is known about whether the underlying mechanisms of mental health outcomes differ between ...
Added: July 15, 2026
Global, regional, and national burden of tuberculosis and multidrug-resistant tuberculosis by HIV status, 1990–2023: a systematic analysis for the Global Burden of Disease Study 2023
Vlassov V., The Lancet Infectious Diseases 2026 P. 1–12
Background Tuberculosis (TB) is the leading global cause of death from a single infectious agent. Recent reductions in global health funding have threatened TB control, making comprehensive assessment of TB, HIV-related TB, and drug-resistant TB burdens before these disruptions essential for shaping effective responses. The WHO End TB Strategy sets targets of a 95% reduction in ...
Added: July 7, 2026
Оценка моделей LLM по степени готовности решать задачи управления в области ESG
Storchevoy M., Mylnikov L., Чернышев В. В. et al., / SSRN. Серия "Working Papers". 2025.
Внимание к охране природы принимает все большую значимость для бизнеса с одной стороны в связи с ужесточением в природоохранном законодательстве, а с другой в связи с использованием ESG рейтингов при принятии решений о коммерческой деятельности компаний. Составление рейтинга LLM систем, способных оказывать консультационные услуги в области природоохраны и ESG, позволяет осуществить выбор такой системы для ...
Added: September 18, 2025
Causal Estimands for Policy Evaluation and Beyond
Sokolov B., / Series OSF "SocArXiv". 2025.
This paper reviews various estimands used in modern scientific and applied research to operationalize causal inquiries within the Rubin Causal Model framework. I first introduce the most widely utilized average treatment effects, such as ATE, ATT, and ATC. I then describe their popular extensions, including those targeting local and conditional treatment effects; causal interactions and mediation; effects ...
Added: May 6, 2025
Cultural characteristics of Digital Ecosystem Product Teams and Operational Efficiency
Ovanesova Y., Moshiashvili M. M., Типсина Н. О., / Series "Working Papers". 2021.
The purpose of this article is to analyze and evaluate the cultural characteristics of the digital ecosystem product teams leaders and operational efficiency. Using binary choice models (the main conclusions were made on the basis of logit regressions), has been found a significant negative relationship between the probability of achieving business goals by a team ...
Added: February 17, 2025
Versions of least-squares k-means algorithm for interval data
Mirkin B., Parinov A., Halynchyk M. et al., / Series WP7 "Математические методы анализа решений в экономике, бизнесе и политике". 2024.
Recently, k-means clustering has been extended to the so-called interval data. In contrast to conventional data case, the interval data feature values are intervals rather than single reals. This paper further explores the least-squares criterion for k-means clustering to tackle the issue of initialization, that is, finding a proper set of initial cluster centers at ...
Added: November 26, 2024
Текущее состояние и потенциал применения информационно-аналитических технологий при решении задач управления в здравоохранении: мнение врачей и экспертов сферы здравоохранения
Русских С. В., Tarasenko E. A., Москвичева Л. И. et al., Профилактическая медицина 2023 Т. 26 № 3 С. 39–50
In recent years in Russia, information and analytical technologies have been increasingly used in healthcare. Therefore, analyzing the opinion of doctors and healthcare experts on the current practice and the potential of the use of information and analytical technologies in solving management issues becomes highly urgent. Objective. To study the opinion of doctors and health ...
Added: April 18, 2023
Fairness of Machine Learning Algorithms in Demography
Emmanuel I. C., Mitrofanova E., / Series 4064475 "ArXiv Preprint". 2022.
The paper is devoted to the study of the model fairness and process fairness of the Russian demographic dataset by making predictions of divorce of the 1st marriage, religiosity, 1st employment and completion of education. Our goal was to make classifiers more equitable by reducing their reliance on sensitive features while increasing or at least ...
Added: May 31, 2022
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