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Мутация A3243G в митохондриалыюй ДНК при диссекции магистральных артерий головы
Журнал неврологии и психиатрии им. С.С. Корсакова. 2012. Т. 112. № 1.
Калашникова Л. А., Добрынина Л. А., Сахарова А. В., Чайковская Р. П., Nazarova M., Мир-Касимов М., Патрушев Л., Коновалов Р. Н., Процкий С.
Language:
Russian
Mokienko O., Люкманов Р. Х., Bobrov P. et al., Современные технологии в медицине 2023 Т. 15 № 6 С. 63–73
Brain–computer interfaces (BCIs) are a group of technologies that allow mental training with feedback for post-stroke motor recovery. Varieties of these technologies have been studied in numerous clinical trials for more than 10 years, and their construct and software are constantly being improved. Despite the positive treatment results and the availability of registered medical devices, ...
Added: March 19, 2026
Люкманов Р. Х., Исаев М. Р., Mokienko O. et al., Анналы клинической и экспериментальной неврологии 2023 Т. 17 № 4 С. 82–88
Introduction. Non-invasive brain–computer interfaces (BCIs) enable feedback motor imagery [MI] training in neurological patients to support their motor rehabilitation. Nowadays, the use of BCIs based on functional near-infrared spectroscopy (fNIRS) for motor rehabilitation is yet to be investigated. Objective: To evaluate the potential fNIRS BCI use in hand MI training for comprehensive post-stroke rehabilitation. Materials ...
Added: March 18, 2026
Mokienko O., Современные технологии в медицине 2025 Т. 17 № 2 С. 73–85
The advancement of novel technologies for the rehabilitation of post-stroke patients represents a significant challenge for a range of interdisciplinary fields. Near-infrared spectroscopy (NIRS) is an optical neuroimaging technique based on recording local hemodynamic changes at the cerebral cortex level. The technology is typically employed in post-stroke patients for diagnostic purposes, including the assessment of ...
Added: March 18, 2026
Тарасов В. В., Lyaskovsky A., В кн.: Сборник трудов XXII Международной научно-практической конференции. Посвящается 80-летию президента РТУ МИРЭА, академика РАН, доктора физико-математических наук, профессора А.С. Сигова.: Ассоциация выпускников и сотрудников ВВИА им. проф. Жуковского, 2025. С. 198–201.
Stroke is a leading cause of long-term motor impairment, significantly limiting patients' functional capabilities and reducing their quality of life. Modern approaches to post-stroke rehabilitation include the use of robotic technologies aimed at restoring motor function. This article presents the concept of a robotic device that uses an on-demand assistance approach to adapt the level ...
Added: February 5, 2026
Korotkova E. V., S. P. Kulikova, Kotyusov A. I. et al., Neuroscience and Behavioral Physiology 2025 Vol. 55 No. 2 P. 327–339
While the outcomes of stroke in adults are relatively well-studied, our understanding of pediatric stroke remains limited. One of the key questions is how the characteristics of a stroke—such as its size and location—influence cognitive outcomes as children grow. In particular, extensive infarcts, widely linked to poor prognoses in adult stroke patients, have not been ...
Added: April 7, 2025
Buivolova O., Stepanova V., Soloukhina O. et al., Журнал неврологии и психиатрии им. С.С. Корсакова 2025 Т. 125 № 3‑2 С. 28–34
Objective. To establish the validity of a new diagnostic tool — Russian Aphasia Test (RAT) — by comparing the results of its completion with those of “The Scale for Appraising the Severity of Language Disorders in Persons with Local Brain Lesions” (Wasserman Scale), traditionally used in Russian-speaking contexts.
Material and methods. One hundred participants who had ...
Added: April 2, 2025
Safonova A., В кн.: Psy-Вышка: сборник материалов Международной научной конференции (Москва, 20–22 мая 2021 г.).: СПб.: Скифия-принт, 2022.
In this study, the influence of the context of movement on the sensorimotor rhythms of the EEG was studied when observing the movements of various objects.
The results obtained suggest that the introduction of a context about the movement of an extraneous object, namely, the connection of the observed movement with a human limb, leads to ...
Added: August 29, 2023
Pavlyuchenkova A., Roman A. Zinovkin, Makievskaya C. et al., Life Sciences 2022 Vol. 288 Article 120174
FcεRI-dependent activation and degranulation of mast cells (MC) play an important role in allergic diseases. We have previously demonstrated that triphenylphosphonium (TPP)-based antioxidant SkQ1 inhibits mast cell degranulation, but the exact mechanism of this inhibition is still unknown. This study focused on investigating the influence of TPP-based compounds SkQ1 and C12TPP on FcεRI-dependent mitochondrial dysfunction and signaling during MC ...
Added: December 10, 2022
Lyamzaev K., Zinovkin R., Chernyak B., Journal of Cellular Physiology 2022 Vol. 237 No. 5 P. 2345–2356
Mitochondria are dynamic organelles that regulate various intracellular signaling pathways, including the mechanisms of programmed cell death, differentiation, inflammation, and so on. Mitochondria may be extruded as membrane enveloped or as free organelles during developmental processes, inflammatory activation, and in the process of “garbage clearance” of damaged mitochondria in postmitotic cells. Extracellular mitochondria can be ...
Added: December 10, 2022
Razmyslovich A., Buivolova O., Samoukina A. et al., The Russian Journal of Cognitive Science 2021 Vol. 8 No. 3 P. 33–45
Non-invasive brain stimulation (NIBS) techniques combined with behavioral speech/language therapies have recently been suggested as a promising method for language recovery in people with aphasia (PWA). Repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (tDCS) are currently the most common types of NIBS for aphasia rehabilitation. In this study, we combined either rTMS ...
Added: June 9, 2022
Bogolyubova-Kuznetsova A., Биохимия 2018 Т. 83 № 2
Ультрацентрифугирование в градиенте плотности остается самым надежным способом получения высоко-очищенных препаратов митохондрий. Однако не всегда у исследователя есть необходимое оборудование, кроме того данный метод обладает невысоким выходом, что может иметь критическое значение, когда исходный биологический материал весьма скуден. В данной работе описан комбинированный метод выделения митохондрий для протеомных исследований, объединяющий разрушение клеток ультразвуком, дифференциальное центрифугирование ...
Added: March 4, 2022
Zyryanov A., Stupina E., Gordeyeva E. et al., Brain and Language 2022 Vol. 224 Article 105057
Unlike stroke, neurosurgical removal of left-hemisphere gliomas acts upon a reorganized language network and involves brain areas rarely damaged by stroke. We addressed whether this causes the profiles of neurosurgeryand stroke-induced language impairments to be distinct. K-means clustering of language assessment data (neurosurgery cohort: N = 88, stroke cohort: N = 95) identified similar profiles ...
Added: December 8, 2021
Nazarova M., Цивилева В., Иванов Т. et al., European Stroke Journal 2021 Vol. 6 P. 248–248
Background and Aims: The possibility to evoke a motor response
(MEP) in a hand muscle by transcranial magnetic stimulation (TMS) is a
common proxy of the corticospinal tract integrity after a motor stroke.
However, it is still not clear how many muscles should be studied, and
which muscles are preferable to probe. Here we aimed to investigate
corticospinal excitability in ...
Added: November 1, 2021
Vadinova V., Buivolova O., Dragoy O. et al., Neuropsychologia 2020 Vol. 147 Article 107591
Background
Implicit-statistical learning (ISL) research investigates whether domain-general mechanisms are recruited in the linguistic processes that require manipulation of patterned regularities (e.g. syntax). Aphasia is a language disorder caused by focal brain damage in the left fronto-temporal-parietal network. Research shows that people with aphasia (PWA) with frontal lobe lesions manifest convergent deficits in syntax and ISL mechanisms. ...
Added: September 15, 2020
Nazarova M., Novikov P., Nikulin V. et al., Нервно-мышечные болезни 2020 Т. 10 № 1 С. 64–74
Transcranial magnetic stimulation is a method of focal non-invasive brain stimulation, characterized by high spatial and temporal resolution. To date, diagnostic transcranial magnetic stimulation has been used in clinical practice primarily to assess an involvement of the upper motor neurons and to measure the velocity of the neuronal impulse propagation. However, in the last 10 ...
Added: June 4, 2020
Мехряков С. А., Кулеш А. А., Покаленко Е. А. et al., Неврология, нейропсихиатрия, психосоматика (Российская Федерация) 2020 Т. 12 № 1 С. 13–21
Patent foramen ovale (PFO) is an important cause of embolic cryptogenic stroke (ECS) in young patients. The main mechanism in this case is paradoxical embolism (PE), the basis for which is a right-to-left (R-L) shunt. Objective: to comparatively characterize patients who have undergone ECS, with and without an R-L shunt, as evidenced by transcranial Doppler ...
Added: February 25, 2020
Vlassov V., Neuroepidemiology 2017 Vol. 49 No. 1-2 P. 45–61
BACKGROUND:
The burden of stroke in low- and middle-income countries (LMICs) is large and increasing, challenging the already stretched health-care services.
AIMS AND OBJECTIVES:
To determine the quality of existing stroke-care services in LMICs and to highlight indigenous, inexpensive, evidence-based implementable strategies being used in stroke-care.
METHODS:
A detailed literature search was undertaken using PubMed and Google scholar from January ...
Added: January 18, 2019
Vlassov V., New England Journal of Medicine 2018 Vol. 379 No. 25 P. 2429–2437
BACKGROUND: The lifetime risk of stroke has been calculated in a limited number of selected populations. We sought to estimate the lifetime risk of stroke at the regional, country, and global level using data from a comprehensive study of the prevalence of major diseases.
METHODS: We used the Global Burden of Disease (GBD) Study 2016 estimates ...
Added: December 29, 2018
Shendyapina M., Kuzmina E., Kazymaev S. et al., Neuropsychology 2019 Vol. 33(1) P. 77–92
Abstract
OBJECTIVE:
The Oxford Cognitive Screen (OCS) is a screening tool for the assessment of poststroke deficits in attention, memory, praxis, language, and number processing. The goal of the present study was to develop a Russian version of the OCS (Rus-OCS) via translation of the original battery, its cultural and linguistic adaptations, and reporting preliminary findings on ...
Added: November 1, 2018
Ulanov M., Shtyrov Y., Stroganova T., Журнал высшей нервной деятельности им. И.П. Павлова 2018 Т. 68 № 6 С. 703–718
In recent years, possible therapeutic effects of transcranial direct current stimulation (tDCS) have
been widely investigated in studies dealing with different types of neural pathologies. Initially, tDCS
was applied for treatment of patients with motor stroke; later on, it was introduced into studies of
patients with Alzheimer’s disease, multiple sclerosis, Parkinson’s disease, schizophrenia and poststroke aphasia. Recent reviews ...
Added: October 25, 2018
Malyutina S., Искра Е. В., Consilium Medicum 2017 Т. 19 № 2.1 С. 56–59
Афазия (нарушения сформировавшейся речи вследствие поражений головного мозга) серьезно ограничивает возможности коммуникации и отрицательно влияет на качество жизни пациентов. Зачастую социальная активность и качество жизни пациентов с афазией снижаются, в том числе из-за низкой общественной информированности и, как следствие, неготовности общества к их интеграции; также успех реабилитации во многом зависит от информированности родственников пациентов. Нами ...
Added: October 5, 2018
Nazarova M., В кн.: Восстановительная неврология, инновационные технологии в нейрореабилитации.: М.: Издательство "Медицинское информационное агентство", 2016. Гл. 6 С. 138–158.
Глава 6. Зеркальная терапия в нейрореабилитации (М.А. Назарова)...........................................138
6.1. Общее понятие о зеркальной терапии............................................................... 138
6.2. Пластичность сенсорных и моторных карт мозга человека...........................139
6.3. Фантомные боли и история открытия ЗТ..........................................................141
6.4. Принципы и методология ЗТ.............................................................................. 144
6.5. Зеркальная иллюзия/иллюзорное восприятие движения у здоровых..............................................................................................................145
6.6. Механизмы ЗТ и зеркальной иллюзии...............................................................147
6.7. Область применения ЗТ....................................................................................... 151
6.7.1. ЗТ в реабилитации после инсульта.......................................................... 151
6.7.2. ЗТ при ...
Added: October 20, 2016
М.: Издательство "Медицинское информационное агентство", 2016.
В первой части книги раскрываются современные представления о двигательном контроле, а также теориях и подходах двигательного обучения, на основе которых возникли многие инновационные реабилитационные технологии, составляющие основу современной восстановительной неврологии. В этой же части обсуждаются современные взгляды на нейропластичность, в том числе на функциональные и структурные изменения в головном мозге человека, лежащие в основе механизма ...
Added: October 20, 2016