Сборник практических заданий по экологии
Many environmental stimuli present a quasi-rhythmic structure at different timescales that the brain needs to decompose and integrate. Cortical oscillations have been proposed as instruments of sensory de-multiplexing, i.e., the parallel processing of different frequency streams in sensory signals. Yet their causal role in such a process has never been demonstrated. Here, we used a neural microcircuit model to address whether coupled theta–gamma oscillations, as observed in human auditory cortex, could underpin the multiscale sensory analysis of speech. We show that, in continuous speech, theta oscillations can flexibly track the syllabic rhythm and temporally organize the phoneme-level response of gamma neurons into a code that enables syllable identification. The tracking of slow speech fluctuations by theta oscillations, and its coupling to gamma-spiking activity both appeared as critical features for accurate speech encoding. These results demonstrate that cortical oscillations can be a key instrument of speech de-multiplexing, parsing, and encoding.
We compare the population parameters of two common species of rats, Maxomys surifer and Niviventer huang, living in a partially disturbed tropical forest in the Cat Tien National Park (South Vietnam). Populations of M. surifer are characterized by a high proportion of young individuals and a small number of residents, which is associated with intensive population renewal processes. Populations of the N. huang, on the contrary, are distinguished by a large number of residents and a high degree of survival
Environmental protest has become the main form of political protest in Russia in 2018-2019. The decision to open a landfill for waste disposal at Shies station in the Arkhangelsk region caused dissatisfaction of residents with the policies of regional elites and strengthened the position of environmental protest in the whole country. In the article we identify the politicization of environmental discourse using the case of the landfill at Shies. We show how the political decision of the authorities, which was excluded from the public discussion and competing discourses, has led to the dominant discourse construction of an environmental problem as a political one among citizens. Based on 19 semi-structured interviews with residents of the Arkhangelsk region we conclude that the politicization of environmental discourse and high political mobilization occurred due to three main mechanisms that worked simultaneously. Citizens assess the decision as illegitimate, unfair and attributed responsibility to certain political leaders.
Hypoxia of trophoblast cells is an important regulator of normal development of the placenta. However, some pathological states associated with hypoxia, e.g. preeclampsia, impair the functions of placental cells. Oxyquinoline derivative inhibits HIF-prolyl hydroxylase by stabilizing HIF-1 transcription complex, thus modeling cell response to hypoxia. In human choriocarcinoma cells BeWo b30 (trophoblast model), oxyquinoline increased the expression of a core hypoxia response genes along with up-regulation of NOS3, PDK1, and BNIP3 genes and down-regulation of the PPARGC1B gene. These changes in the expression profile attest to activation of the metabolic cell reprogramming mechanisms aimed at reducing oxygen consumption by enabling the switch from aerobic to anaerobic glucose metabolism and the respective decrease in number of mitochondria. The possibility of practical use of the therapeutic properties of oxyquinoline derivatives is discussed.