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Экспрессия гена INK4A в клетках рака мочевого пузыря, ассоциированного с вирусом папиллом человека 16-го типа
БЮЛЛЕТЕНЬ ЭКСПЕРИМЕНТАЛЬНОЙ БИОЛОГИИ И МЕДИЦИНЫ, Россия. 2010. Т. 149. № 2. С. 204–208.
Волгарева Г. М., Завалишина Л. Э., Головина Д. А., Андреева Ю. Ю., Ермилова В. Д., Трофимова О. Б., Куевда Д. А., Шипулина О. Ю., Глазунова В.А., Чен Ш., Павлова Л. С., Чебан Н. Л., Матвеев В. Б., Франк Г. А.
Language:
Russian
Vlassov V., The Lancet Public Health 2026 P. 1–6
Background
Road injuries are a leading cause of mortality and morbidity worldwide. Years of international efforts have aimed to strengthen policy engagement, including the 2020 UN General Assembly's proclamation of the Second Decade of Action for Road Safety (2021–30), targeting a 50% reduction in road traffic deaths and serious injuries by 2030. The aim of this ...
Added: July 25, 2026
Kivalov S., Legacy Theses & Dissertations (2009 - 2024), 2024.
An observed 20-30% increase in forest net ecosystem exchange (NEE) on partly cloudy days is often attributed to there being more uniform canopy illumination by diffuse radiation when clouds are present. However, the sky on such days is typically populated by fair-weather cumulus clouds, bringing dynamically changing shadow-to-light conditions on the order of minutes to ...
Added: July 24, 2026
Авксентьева М. В., Ашихмин Я. И., Ашихмина О. В. et al., М.: ФГБУ "Издательство "Наука", 2023.
Предложены основные направления совершенствования планирования, организации и оплаты медицинской помощи, лекарственного обеспечения, информатизации и оценки технологий здравоохранения. Рекомендованы такие мероприятия, как конкретизация программы государственных гарантий бесплатного оказания гражданам медицинской помощи, создание системы общедоступного лекарственного обеспечения, использование клинико-статистических групп для оплаты медицинской помощи при ряде хронических неинфекционных заболеваний в амбулаторных условиях, формирование механизма привлечения соплатежей при ...
Added: July 16, 2026
Михайлов И. А., Опухоли женской репродуктивной системы 2025 Т. 21 № 1 С. 86–105
Цель исследования – определить наиболее целесообразную стратегию скрининга и ранней диагностики рака шейки матки (РШМ) в Российской Федерации с точки зрения клинической (диагностической) и экономической эффективности.
Материалы и методы. Для оценки клинической (диагностической) эффективности различных стратегий скрининга проведен систематический обзор публикаций об исследованиях, оценивающих эффективность применения цитологического исследования и тестирования на вирус папилломы человека (ВПЧ) с целью диагностики ...
Added: July 16, 2026
Иванова А. А., Коган С. А., Горбунова Т. В. et al., Менеджер здравоохранения 2026 № 3 С. 96–105
The research r elev anc e is determined by the demand for telemedicine consultations (TMC) as one of health care digitalization pathways in Russian Federation. Telemedicine, regardless of the field, continues to prove its significant role, saving health resources without losing medical care quality. The TMC is regulated by federal level framework. Each year the ...
Added: July 16, 2026
Михайлов И. А., Machine Learning and Knowledge Extraction 2026 Vol. 8 No. 1 Article 8
Whole-slide histology images (WSIs) can exceed 100 k × 100 k pixels, making direct pixel-level segmentation infeasible and requiring patch-level classification as a practical alternative for downstream WSI segmentation. However, most approaches either treat patches independently, ignoring spatial and biological context, or rely on deep graph models prone to oversmoothing and loss of local tissue ...
Added: July 16, 2026
Хайлова Ж. В., Омельяновский В. В., Михайлов И. А. et al., Менеджер здравоохранения 2026 № 4 С. 41–52
The urgency of the problem of organizing effective medical care for cancer patients is determined by the steady trend of increasing incidence of malignant neoplasms, the high proportion of this pathology in the structure of overall mortality, as well as significant medical, demographic and socio-economic losses for society.Purpose of the st udy is to conduct ...
Added: July 16, 2026
Михайлов И. А., Здоровье мегаполиса 2026 Т. 7 № 2 С. 7–16
Objective. To evaluate the impact of a series of organizational measures for implementing innovative medical technology in a multidisciplinary hospital on patient quality of life based on patient self-assessments. Results. Patients who received care using innovative medical technology within a systemic organizational approach demonstrated a significantly higher level of overall satisfaction with the quality of care. ...
Added: July 16, 2026
Ахапкина Е. С., Омельяновский В. В., Тулупова О. Н. et al., Медицинские технологии. Оценка и выбор 2026 Т. 48 № 2 С. 70–77
OBJECTIVE
To analyze international approaches to assessing the labor complexity for different specialists with higher medical education (physicians).
MATERIAL AND METHODS
We performed a systematic searching and content analysis of foreign and national studies and documents devoted to labor complexity of different specialists with higher medical education (doctors). A group of experts among the authors of this study discussed and identified significant factors in assessing complexity.
RESULTS
There are 2 main systems to assess physician workload complexity in foreign countries. The first approach is based ...
Added: July 16, 2026
Михайлов И. А., Annals of Hematology 2025 Vol. 104 P. 2707–2715
Vamotinib (PF-114) is a 3rd -generation, ATP-competitive oral tyrosine kinase inhibitor (TKI) active against wild-type and mutated BCR::ABL1 isoforms including BCR::ABL1T315I. We present final results of a phase-1 vamotinib dose-escalation study to identify maximum tolerated dose (MTD) and dose-limiting toxicity (DLT) followed by expansion cohorts. 51 subjects with chronic myeloid leukaemia (CML) failing ≥ 1 2nd generation TKI or with BCR::ABL1T315I were ...
Added: July 16, 2026
Arina Bukina, Eritsyan K., Antonova N. et al., Frontiers in Psychology 2026 Vol. 17 Article 1824428
Background:
Numerous studies have shown that indigenous populations experience poorer health outcomes compared to people with other backgrounds. However, the interpretation of these disparities remains challenging due to differences in living conditions and social environments, as well as by potential measurement-related biases. Little is known about whether the underlying mechanisms of mental health outcomes differ between ...
Added: July 15, 2026
Stepanov A., Kivalov Sergey N., Vasenev I., Sustainability 2026 Vol. 18 No. 13 Article 6879
The carried-out microfield model research was aimed at identifying patterns in the dynamics of soil CO2 effluxes depending on the locally occurring hydrothermal regimes of regenerated lawn ecosystems on peat-sand substrates with different peat contents. Monitoring was carried out every ten days from 21 April 2019 to 30 October 2019 and included measurements of soil ...
Added: July 8, 2026
Ledesma J. R., Zhang M., Liew M. F. et al., The Lancet Infectious Diseases 2026 P. 1–12
Background
Tuberculosis (TB) is the leading global cause of death from a single infectious agent. Recent reductions in global health funding have threatened TB control, making comprehensive assessment of TB, HIV-related TB, and drug-resistant TB burdens before these disruptions essential for shaping effective responses. The WHO End TB Strategy sets targets of a 95% reduction in ...
Added: July 7, 2026
Окнина Л. Б., Подлепич В. В., Sieber I. et al., Физиология человека 2026 Т. 52 № 3 С. 5–15
The aim of this study was to evaluate the frequency following response (FFR) for the analysis of the intact perception of syllables in humans. For this purpose, event-related potentials (ERPs) in response to isolated Russian syllables were recorded and analyzed in 29 healthy persons in two frequency ranges, standard (1-40 Hz) and high frequency (70-150 ...
Added: June 30, 2026
Liapin G., Vlassov V., DIALOGUES IN HEALTH 2026 Vol. 8 Article 100317
Objectives
Due to the economic growth at the end of the 20th century, people in low-income countries live longer but still spend most of their income on food. These countries, as well as affluent countries, demonstrate a rising prevalence of obesity. The interplay of longevity and obesity at different levels of economic development is not clear.
Methods
We ...
Added: June 29, 2026
Podolskaia E., Вопросы лесной науки 2022 Т. 5 № 4 Статья 115
Paper presents an overview of history and current research state on the use of remote sensing data from
space to recognize roads for the regional projects. We have characterized principles of road detection on the imagery. A group of direct deciphering signs used in combinations such as brightness and texture, geometry and
brightness. Three research directions with ...
Added: June 25, 2026
Князева С. В., Ершов Д. В., Никитина А. Д. et al., Современные проблемы дистанционного зондирования Земли из космоса 2025 Т. 22 № 6 С. 383–386
This brief report summarizes the key outcomes of the IX All-Russia (with International Participation)
Scientific Conference “Aerospace Methods and Geoinformation Technologies in Forest Science,
Forestry and Ecology”. The conference was held April 15–17, 2025, in Moscow at Isaev Center for
Forest Ecology and Productivity RAS with organizational support from Space Research Institute RAS.
The conference was attended about 130 ...
Added: June 24, 2026
Ekaterina S. Podolskaia, Sinitsina A., European Journal of Forest Engineering 2026 Vol. 12 No. 1 P. 7–22
Machine learning in transport modeling has become a trend in science and industry. In this paper, we observe its main directions and focus on a dataset of seasonal road creation. Seasonality as a parameter in transport modeling has a significant impact on transport scenarios but is underestimated worldwide and in Russia, despite modern data challenges. ...
Added: June 24, 2026
Ryskina H., Лобаева Т. А., Ануркина А. И., Ваш формат, 2025.
Я
Эволюция, экология, генетика человека, медицинская паразитология. Практикум. Аннотация
Аннотация к практикуму «Эволюция, экология, генетика человека, медицинская паразитология»
Учебное пособие «Эволюция, экология, генетика человека, медицинская паразитология. Практикум» (авторы: Лобаева Т. А., Рыскина Е. А., Ануркина А. И.; издательство «Ваш формат», 2025 год, 194 страницы) предназначено для студентов высших учебных заведений. Цель практикума — обеспечить комплексное освоение ключевых разделов биологии с акцентом на их прикладное значение в медицине. ...
Added: June 23, 2026
Herbert A., Cherednichenko O., Lybrand T. et al., International Journal of Molecular Sciences 2025 Vol. 26 No. 6 Article 2422
The double-stranded RNA editing enzyme ADAR1 connects two forms of genetic programming, one based on codons and the other on flipons. ADAR1 recodes codons in pre-mRNA by deaminating adenosine to form inosine, which is translated as guanosine. ADAR1 also plays essential roles in the immune defense against viruses and cancers by recognizing left-handed Z-DNA and ...
Added: June 22, 2026
Пузанов Г., Сенченко В., Молекулярная биология 2021 Т. 55 № 4 С. 531–542
Small SCP phosphatases CTDSP1, CTDSP2, and CTDSPL specifically dephosphorylate serine and threonine residues in protein molecules. The enzymes are involved in regulating activity of RNA polymerase II at the transition from transcription initiation to elongation, regulating expression of neuron-specific genes, and activating the key cell-cycle protein pRb at the G1/S boundary. In addition, the substrates ...
Added: October 11, 2022
Волгарева Г. М., Завалишина Л. Э., Трофимова О. Б. et al., Архив патологии 2010 Т. 72 № 4 С. 24–27
Проведено комплексное обследование больной рецидивирующим раком мочевого пузыря. Ранее в первичной опухоли, удаленной у нее в 2004 г., выявлена ДНК вируса папилломы человека (ВПЧ) 16-го типа, мРНК, соответствующая онкогену Е7 ВПЧ16, а также белок Е7 ВПЧ16. Больная является курильщицей, более 20 лет она проработала на химическом производстве. При рецидиве в 2009 г. ДНК ВПЧ типов ...
Added: July 14, 2015