Применение фозиноприла при лечении пожилых больных с мягкой и умеренной эссенциальной артериальной гипертензией

Мартынов А. И.; Остроумова О. Д.; Мамаев В. И.; Н. А. Варако; Нестерова М. В.; Рыбкина Т. Е.; Гедгафова С. Ю.

Publications

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Применение фозиноприла при лечении пожилых больных с мягкой и умеренной эссенциальной артериальной гипертензией

Российские медицинские вести. 2000. № 2. С. 54–62.

Мартынов А. И., Остроумова О. Д., Мамаев В. И., Varako N. A., Нестерова М. В., Рыбкина Т. Е., Гедгафова С. Ю.

Research target: Basic Medicine Health Studies

Language: Russian

Keywords: сердечно-сосудистые заболевания артериальная гипертензия фозиноприл

Политика в отношении абортов и оценка их распространенности в мире и в России

Sakevich V. I., Демографическое обозрение 2026 Т. 13 № 3 С. 4–28

The article analyzes modern legislation regarding artificial termination of pregnancy in countries around the world. Depending on the grounds on which abortion is permitted, five groups of countries are distinguished. Estimates have shown that about 60% of women of reproductive age live in countries with liberal legislation, where abortion is allowed at the request of ...

Added: October 15, 2026

Household environmental management practices, community engagement, and self-reported malaria incidence in urban and rural communities of Malawi

Lungu M. M., Davitadze A., Frontiers in Public Health 2026 Vol. 14 Article 1919768

Malaria control in Malawi relies primarily on long-lasting insecticide-treated nets (LLITNs) and indoor residual spraying (IRS), but transmission remains heterogeneous across districts. Previous research indicates that community-based environmental management strategies, such as routine drainage maintenance, vegetation removal, and effective household waste disposal, may reduce environmental conditions conducive to malaria vector proliferation. This study investigated the ...

Added: October 15, 2026

Pericyte-derived cancer-associated fibroblasts correlate with poor survival and are enriched after chemoradiotherapy in glioblastoma

Aly Ismailov, Poptsova M., Plos One 2026 Vol. 21 No. 9 Article e0355902

Added: October 2, 2026

Изменения в организации медицинской помощи, обусловленные новыми цифровыми технологиями. Аналитический обзор

Shishkin S., Almazov A., Vlassov V. et al., Электронный научный журнал "Социальные аспекты здоровья населения" 2026 Т. 72 № 4 Статья 4

Abstract Significance. The epidemiological, clinical, and socioeconomic effects of healthcare digitalization are actively discussed in the scientific literature. Less attention has been paid to changes in the organization of healthcare resulting from the introduction of digital technologies. These changes have not been the subject of specific research. However, digital technologies is becoming a driver for the ...

Added: September 29, 2026

Применение бета-адреноблокаторов в реальной клинической практике. Анализ результата опроса врачей экспертами Евразийской Ассоциации Терапевтов

Арутюнов Г. П., Тарловская Е. И., Батлук Т. И. et al., Российский кардиологический журнал 2025 Т. 30 № 10 С. 111–120

The use of beta-blockers (BB) plays a crucial role in the treatment of cardiovascular diseases. However, there are significant discrepancies with current guidelines in real-world practice. The main issues related to suboptimal dosing regimens and poor medication adherence reduce the effectiveness of therapy and worsen the prognosis of patients. Under the auspices of the Eurasian ...

Added: September 28, 2026

Онтологический разрыв: когда Другой — алгоритм

Ugleva A. V., Социологическое обозрение 2026 Т. 25 № 3 С. 268–293

This article undertakes a socio-philosophical analysis of a situation in which the place of the Other within the structure of subjective experience is occupied by an algorithmic agent – an entity that simulates understanding yet remains devoid of genuine subjectivity. To investigate this configuration, the author turns to psychiatric practice as a representative case study: ...

Added: September 26, 2026

Экспертная оценка ответов больших генеративных моделей на запросы врачей в клинической практике

Тыров И. А., Васильев Ю. А., Владзимирский А. В. et al., Труды Института системного анализа Российской академии наук 2026 Т. 76 № 3 С. 79–89

Large language models (LLMs) in healthcare currently attract significant interest. This study compared GigaChat and YandexGPT by evaluating 1,200 LLM-generated responses to physician queries from outpatient and inpatient settings across 7 topics. Thirteen expert physicians assessed the responses using a 5-point scale across five criteria: relevance, correctness, safety, completeness, and language literacy. We performed paired ...

Added: September 22, 2026

Изоформы микроРНК hsa-miR‐143-3p как регуляторы HK2 и SERPINE1 при гипоксии трофобласта и преэклампсии

Чеботарева О. Е., Пирогов А. А., Antipenko I. et al., Доклады российской академии наук. Науки о жизни 2026 Т. 529 № 1 С. 389–395

Preeclampsia (PE) is a severe obstetric complication caused by chronic placental ischaemia. Genome-wide profiling of microRNA isoforms in two trophoblast hypoxia models (CoCl2 and the oxyquinoline derivative neuradapt, BeWo b30 cells) and clinical PE samples (placental tissue, syncytiotrophoblast vesicles) revealed concordant downregulation of hsa-miR-143-3p isoforms. Under a strict fold-change threshold, the canonical isoform (21 nt) ...

Added: September 16, 2026

Validation of novel naturalistic limb movement stimuli for studying biological motion perception in adults

Koriakina M., Ntoumanis I., Blagoveshchensky E. et al., Frontiers in Human Neuroscience 2026 Vol. 20 Article 1754368

Introduction: Understanding how we perceive and interpret the movements of other living beings is fundamental to social interaction, survival, and navigating our dynamic environment. Traditional studies of biological motion perception have predominantly employed simplified stimuli, such as point-light displays, which sacrifice ecological validity for experimental control. Methods: To overcome this limitation, we created a novel stimulus set featuring ...

Added: September 15, 2026

Discovering New Orthologous Groups with P-COGs

Bug D. S., Kuzovenkova D. A., Tishkov A. V. et al., Biochemical Genetics 2026

Deciphering the evolutionary history of genes is foundational for biomedical research, enabling the identification of compensatory mutations in disease-associated genes and the selection of evolutionarily relevant model organisms. However, challenges of multi-isoform handling, the presence of incomplete genomes/proteomes initial datasets, and problems of evolutionary history representation are still present. To address these issues, we introduce ...

Added: September 14, 2026

Global burden of amphetamine, cannabis, cocaine and opioid use in 204 countries, 1990–2023: a Global Burden of Disease Study

Kang J., Kim H. J., Kim M. S. et al., Nature Medicine 2026 No. 32 P. 527–544

Added: September 9, 2026

Salivary Antioxidant Capacity and Magnesium in Generalized Anxiety Disorder

Proskurnina E., Liaukovich K., Bychkovskaya L. et al., Metabolites 2023 Vol. 13 No. 1 P. 73

Added: September 7, 2026

Benchmarking Synolitic Graphs for Autism Classification from Multisite Resting-State fMRI

Zaikin A., Vlasenko D., Zakharov D. et al., Diagnostics 2026 Vol. 16 No. 17 Article 2746

Background/Objectives: Synolitic graphs (SGs) were developed for task-based fMRI, where edge weights encode the discriminative power of pairwise regional features; whether similar information can be recovered from resting-state data was untested. We benchmarked SGs for autism spectrum disorder (ASD) classification using the multisite ABIDE-I dataset (871 subjects: 403 subjects with ASD, 468 typical controls; 17 sites; CC200 atlas). Methods: Using ...

Added: August 27, 2026

Measuring the composition and availability of human resources for health by sex in 204 countries and territories, 1990–2023, and workforce gaps for universal health coverage: a systematic analysis for the Global Burden of Disease Study 2023

Knight M., Bienhoff K., A B. et al., The Lancet Public Health 2026 Vol. 11 No. 9 P. e604–e629

Background Understanding the size, gender composition, and cadre mix of the health workforce and how it has evolved across time and locations can inform policies for planning, recruitment, training, and retention of human resources for health (HRH), and improvement of access to the health-care workforce among populations. Using comparable and standardised data sources, we aim to ...

Added: August 25, 2026

Localization in Medical Imaging: A Unified AI Approach for Ovaries, Follicles, and Vertebral Arteries

Moshkin A., Fedorov M., Arlazarov V. et al., Algorithms 2026 Vol. 19 No. 7 Article 523

Artificial intelligence (AI) technologies, which are being actively developed in modern medicine today, increase the speed and quality of patient care. This article mainly seeks to demonstrate the use of various options of computer analysis of clinical images to solve practical problems of increasing the efficiency of routine diagnostics using retrospective analysis, as well as ...

Added: August 17, 2026

Assessing walkability and climate adaptive capacity in relation to urban morphology and historical development

Shartova N., Mironova E., Geo Journal 2026 Vol. 91 Article 78

The historical timeline of urban development profoundly shapes the contemporary form and functionality of cities. Traditionally, cities were planned with limited consideration for the promotion of a healthy urban environment. Using Nizhny Novgorod, Russia, a city that has evolved from a medieval market town to an industrial centre and later into a multifunctional city with ...

Added: August 9, 2026

Global Burden of Elevated LDL-C: Findings From the Global Burden of Disease Study 2023

Razo C., DeCleene N., Johnson C. et al., JAMA - Journal of the American Medical Association 2026 Vol. 336 No. 8 P. 673–696

Importance Elevated low-density lipoprotein cholesterol (LDL-C) is a modifiable risk factor for cardiovascular disease, the leading cause of premature death worldwide. Assessing the LDL-C–related burden is critical for guiding prevention and treatment strategies. Objectives To estimate the global, regional, and national burden of ischemic heart disease and ischemic stroke attributable to elevated LDL-C (relative to 35-54 mg/dL) from ...

Added: August 4, 2026

Нейросетевая система диагностики и прогнозирования развития сердечно-сосудистых заболеваний KARDIONET как источник получения новых медицинских знаний

Думлер А. А., Каракулова Ю. В., Yasnitsky L., В кн.: Искусственный интеллект в решении актуальных социальных и экономических проблем ХХI века : Сборник статей по материалам Десятой всероссийской научно-практической конференции с международным участием (г. Пермь, ПГНИУ, 9–10 октября 2025 г.).: Пермский государственный национальный исследовательский университет, 2025. С. 236–239.

В статье представлены данные использования нейросетевой системы KardioNet для получения новых медицинских данных, таких как «парадокс курильщика», «парадокс физкультуры», меняющие традиционные представления о профилактике сердечно-сосудистых заболеваний и требующие дальнейшего изучения и объяснения. Ключевые слова: сердечно-сосудистые заболевания, нейросетевая система диагностики, ишемическая болезнь сердца, «парадокс курильщика», «парадокс физкультуры» ...

Added: February 15, 2026

Global, Regional, and National Burden of Cardiovascular Diseases and Risk Factors in 204 Countries and Territories, 1990-2023

Stark B., DeCleene N., Desai E. et al., Journal of the American College of Cardiology 2025 Vol. 86 No. 22 P. 2167–2243

Background: Cardiovascular diseases (CVDs) are the leading cause of mortality and are among the foremost causes of disability globally. CVD burden has continued to increase in most countries since 1990, with trends driven by changing exposures to harmful risk factors, population growth, and population aging. Objectives: We report estimates of global, national, and subnational CVD burden, including 18 ...

Added: December 7, 2025

Обзор данных отчетов по развитию электрокардиостимуляции в Российской Федерации за 2008 год

Дроздов В. Н., Федорец В. Н., Бения Р. М. et al., В кн.: Комплексные проблемы сердечно-сосудистых заболеванийТ. 10. Вып. S2 .: Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний, 2021. С. 137–137.

Передовые статьи, обзоры, лекции, клинические случаи. Основные направления в развитии научных исследований по фундаментальным и прикладным проблемам сердечно-сосудистых заболеваний, мультифокального атеросклероза, клинической и профилактической медицины, организации медицинской помощи и общественного здоровья, эпидемиологии сердечно-сосудистых заболеваний. ...

Added: November 25, 2025

Результаты длительного динамического наблюдения уровня поляризации желудочковых электродов MEMBRANE 1450 (ST. JUDE MEDICAL)

Федорец В. Н., Дроздов В. Н., Бения Р. М. et al., В кн.: Комплексные проблемы сердечно-сосудистых заболеванийТ. 10. Вып. S2 .: Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний, 2021. С. 177–177.

Added: March 25, 2025

Socioeconomic inequalities in physiological risk biomarkers and the role of lifestyles among Russians aged 35-69 years

Trias-Llimos S., Cook S., Eggen A. E. et al., International Journal for Equity in Health 2022 Vol. 21 No. 1 Article 51

Socioeconomic inequalities in cardiovascular (CVD) health outcomes are well documented. While Russia has one of the highest levels of CVD mortality in the world, the literature on contemporary socio-economic inequalities in biomarker CVD risk factors is sparse. This paper aims to assess the extent and the direction of SEP inequalities in established physiological CVD risk biomarkers, and to ...

Added: July 21, 2022

Профилактика сердечно-сосудистых заболеваний на предприятии: систематический обзор

Гарипова Ф. Г., Khabibullina A., Aleksandrova E., Здоровье населения и среда обитания 2021 Т. 12 № 12 С. 17–29

Introduction. Cardiovascular diseases have a tremendous impact on the health of the working-age population, causing high economic costs to the country as a whole and to various individual companies. Primary prevention of cardiovascular diseases in the workplace can have a considerable effect on reducing human and labour losses. To determine effective measures in lowering the ...

Added: March 17, 2022

Studying accelerated cardiovascular ageing in Russian adults through a novel deep-learning ECG biomarker

Diez Benavente E., Jimenez-Lopez, F., Attia, Z. I. et al., Wellcome Open Research 2021 Vol. 6 P. 1–12

Background: A non-invasive, easy-to-access marker of accelerated cardiac ageing would provide novel insights into the mechanisms and aetiology of cardiovascular disease (CVD) as well as contribute to risk stratification of those who have not had a heart or circulatory event. Our hypothesis is that differences between an ECG-predicted and chronologic age of participants (δage) would ...

Added: June 10, 2021