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Second-to-fourth digit ratio and facial shape in Buryats of Southern Siberia
Early Human Development. 2020. Vol. 149. P. 105138.
Background: The 2nd-to-4th digit ratio (2D:4D) is a putative predictor of a prenatal exposure to sex hormones. 2D:4D is sexually dimorphic (males<females). Studies, linking digit ratio and full facial shapes among Europeans, show that a low 2D:4D is associated with a set of male-specific facial features. Buryats – Mongolian people from Southern Siberia – demonstrate a different pattern of facial sexual dimorphism than Europeans (narrower and more vertically elongated faces in men as opposed to women).
Aim: The aim of the present study was to investigate the association between facial shape and the 2D:4D in comparison to the pattern of facial sexual dimorphism in Buryats.
Subjects: Buryats: 88 men and 80 women aged 20 ± 2 years.
Outcome measures: To assess relationship between facial shape and 2D:4D we used a geometric morphometric approach based on standardized full-face frontal photographs and direct measurements of the digit lengths among right-handed individuals.
Results: The results revealed that 2D:4D was associated with facial morphology in Buryat men, and to a lesser extent in women. Narrower faces, elongated in the vertical direction, and a narrower lower facial outline, were characteristic of Buryat men with low 2D:4D ratios, which corresponded to the male-like facial shapes in Buryats.
Conclusions: In Europeans, such facial features were reported for men with a high 2D:4D, which corresponded more to female-like European facial shapes. Hence, our results show that sex-specific morphogenesis in humans is multidirectional, and that digit ratio is capable of predicting sex-specific facial traits even in populations with differing sexually-dimorphic morphology.
Diachkova E., Nikulin D., Кубкин Я. В. et al., American Journal of Respiratory and Critical Care Medicine 2026 Vol. 212
Accurate classification of a patient with pulmonary hypertension (PH) into one of five groups is fundamental for appropriate disease management strategies. The time from disease onset to correct diagnosis is unacceptably long in many cases. Chronic thromboembolic pulmonary hypertension (CTEPH) develops as a consequence of venous thromboemboli, resulting in a more pronounced hereditary predisposition to ...
Added: September 23, 2026
Kang J., Kim H. J., Kim M. S. et al., Nature Medicine 2026 No. 32 P. 527–544
Drug use disorders (DUDs) are emerging global public health challenges. Here we investigated the global and regional estimates of the prevalence and burden of DUDs, including amphetamine, cannabis, cocaine and opioid use disorders, from 1990 to 2023 for 204 countries and territories by using the Global Burden of Disease Study 2023. Overall, trends in global ...
Added: September 9, 2026
Khodadoust J., Kulikova S., Khodadoust F., Biomedical Signal Processing and Control 2027 Vol. 129 P. 111284–111284
Acute ischemic stroke (AIS) analysis from two-dimensional (2D) clinical imaging is hindered by uncontrolled slice tilt and geometric inconsistencies that violate the assumptions of pose-agnostic deep learning (DL) models. This paper proposes a unified geometry-aware, frequency-domain framework for tilted slice localization and ischemic stroke segmentation that explicitly decouples pose estimation from lesion analysis. The method ...
Added: September 2, 2026
Elena A. Andresyuk, Natalya O. Porozova, Londaridze G. et al., Frontiers in Oncology 2026 Vol. 16 Article 1875861
Inhibition of the PD-1/PD-L1 axis has become a clinical standard across multiple malignancies, yet durable benefit remains restricted to selected settings, and many biologically rational combinations fail to maintain clinical benefit in late-phase evaluation. This structured, registry-derived narrative review, supported by expert-guided interpretation, was designed to identify the most clinically meaningful development directions among strategies ...
Added: July 31, 2026
Wang R., He Y., Myachykov A. et al., Neuroimage 2026 Vol. 332 Article 121926
Insomnia disorder (ID) exhibits considerable heterogeneity in neuroimaging findings across studies, and whether functional brain alterations are consistent across resting and task states remains unclear. This study aimed to identify neural dysfunction across states in ID and explore its transcriptomic correlates. ...
Added: July 13, 2026
Shestoperov A. I., Ivchenko A., Fomina E. V., Microgravity Science and Technology 2025 Vol. 37 Article 19
The paper is dedicated to the analysis of medico-biological data obtained during locomotor testing of astronauts. Accurate data interpretation plays a crucial role in locomotion system monitoring, prophylaxis of long-duration spaceflight negative effects and thus in the development of an autonomous medical support system for deep space expeditions. During the locomotor testing the astronaut changes ...
Added: June 26, 2026
Vasilev R., Savchenko A., Blinov P. et al., Frontiers in Medicine 2026 Vol. 13 Article 1778404
Automated disease screening systems face challenges when applied to multi-class medical image analysis, particularly under severe class imbalance inherent in clinical datasets. Retinal fundus imaging enables non-invasive screening for multiple ocular and systemic diseases simultaneously, yet current automated systems typically assess risk for only a single pathology or a limited disease range. We developed a ...
Added: June 16, 2026
Zaikin A., Sviridov I., Sosedka A. et al., Technologies 2026 Vol. 14 No. 2 Article 84
High-dimensional tabular data are common in biomedical and clinical research, yet conventional machine learning methods often struggle in such settings due to data scarcity, feature redundancy, and limited generalization. In this study, we systematically evaluate Synolitic Graph Neural Networks (SGNNs), a framework that transforms high-dimensional samples into sample-specific graphs by training ensembles of low-dimensional pairwise ...
Added: May 23, 2026
ЯКУБЕНКО Т. В., Plotnikov S., Ratio et Natura 2024 № 3 (11) Статья 10
The article presents the results of our own research aimed at studying the prospects of using genetic sequencing technologies to identify the risk of having children with genetic abnormalities. ...
Added: May 21, 2026
Андрушкевич О. М., Калиновский А. В., Гаврюшин А. В. et al., Нейрохирургия 2026 Т. 28 № 1 С. 33–42
Background. The application of cortical and subcortical stimulation during awake craniotomy mitigates the risk of persistent postoperative speech deficits. However, the functions of some white matter pathways remain inadequately understood, particularly the frontal aslant tract (FAT) of the dominant hemisphere.
Aim. To evaluate the efficacy of cortical and subcortical stimulation techniques in the localization of glial tumors near ...
Added: May 18, 2026
Garmonova A., Shcheglova D., Камалова Г. Р. et al., Кубанский научный медицинский вестник 2026 Т. 33 № 2 С. 92–110
Introduction. The study analyzes the structure and volume of workload for faculty at Russian medical universities amidst increasing student numbers, rising demands for students' clinical training, scientific output, and continuous professional education. The relevance of the topic stems from the contradiction between official regulatory requirements and the actual excessive workload of medical educators. The aim is to provide ...
Added: April 29, 2026
Krasnov L., Malikov D., Kiseleva M. et al., Journal of Medicinal Chemistry 2026 Vol. 69 No. 8 P. 8838–8851
In this work, we developed a straightforward data-driven approach to predict the cytotoxicity of metal complexes based entirely on their (metal + ligands) composition. To this end, we have manually curated MetalCytoToxDB─a comprehensive experimental database comprising 26,500 IC50 values for 7050 metal complexes against 754 cell lines from 1921 articles. Based on these, machine learning ...
Added: April 23, 2026
Pogodaeva S., Miletina O., Antipova N. et al., Cancers 2025 Vol. 17 No. 19 Article 3228
Pediatric tumors such as neuroblastoma are characterized by a genome-wide ‘transcriptional burden’, surmising the involvement of multiple alterations of gene expression. Search for master regulators of transcription whose inactivation is lethal for tumor cells identified the non-POU domain-containing octamer-binding protein (NONO), a member of the Drosophila Behavior/Human Splicing family known for the ability to form ...
Added: April 15, 2026
Данилова Н. В., Олейникова Н. А., Mikhailov I. et al., М.: КДУ, Университетская книга, 2025.
This textbook contains all the lectures from the pathological anatomy course at the Faculty of Fundamental Medicine of Lomonosov Moscow State University. The total duration of video recordings is over 50 hours. Each lecture has a brief summary. The accessible presentation of the material will allow you to effectively use your knowledge in preparation for ...
Added: March 3, 2026
Екатеринбург: ФГБОУ ВО УГМУ Минздрава России, 2025.
2
Федеральное государственное бюджетное образовательное учреждение
высшего образования
«Уральский государственный медицинский университет»
Министерства здравоохранения Российской Федерации
Научное общество молодых ученых и студентов
Медицинское образование, наука,
практика
Сборник статей X Международной научно-практической конференции
молодых ученых и студентов
Medical education, science, practice
22-23 апреля 2025 г. ...
Added: March 2, 2026
Пермский государственный национальный исследовательский университет, 2025.
Представлены материалы Десятой всероссийской научно-практической конференции с международным участием «Искусственный интеллект в решении
актуальных социальных и экономических проблем ХХI века», которая проводилась 9–10 октября 2025 г. в Перми, ПГНИУ.
Сборник предназначен для научных и педагогических работников, преподавателей, аспирантов, магистрантов, студентов и всех, кто интересуется и занимается проблемами развития и применения методов искусственного интеллекта. ...
Added: February 15, 2026
М.: Эксмо, 2025.
"Сердечная недостаточность"— это современное и всестороннее практическое руководство для врачей, посвященное одной из ключевых проблем кардиологии. В основе книги лежат принципы доказательной медицины, актуальные клинические рекомендации и последние научные достижения в области диагностики и лечения хронической сердечной недостаточности (ХСН).
В руководстве подробно рассмотрены:
- этиология и патофизиологические механизмы развития ХСН;
- современные классификации и критерии диагностики;
- дифференциальная диагностика ...
Added: February 7, 2026
Ларина Е. В., М.: Юрайт, 2026.
-В курсе представлены сведения, необходимые для совершенствования теоретических и практических навыков диагностики, лечения и профилактики хронических неинфекционных заболеваний у мультиморбидных пациентов пожилого и старческого возраста. Информационный материал систематизирован, нагляден, соответствует последним достижениям науки и клинической практики в области внутренних болезней, сопровождается ссылками на современную литературу для самостоятельного изучения. Курс подготовлен в соответствии с действующим Федеральным ...
Added: February 6, 2026
Ларина В. Н., Матвейчук Т. А., Ларина Е. В., Клиницист 2026 Т. 19 № 4 С. 34–42
In response to the global increase in chronic noncommunicable diseases, the World Health Organization and the United Nations have adopted strategies to reduce premature mortality. Improving the health literacy of the population which is defined as a combination of knowledge, motivation and practical skills to maintain health is recognized as a key task for achieving ...
Added: February 6, 2026
Miske O., Abatayo A. L., Daley M. et al., Nature 2026 Vol. 652 P. 126–134
Published claims should be reproducible, yielding the same result when applying the same analysis to the same data. ...
Added: January 19, 2026
Pothi.com, 2025.
Материалы XXXVIII международной научно-практической конференции ...
Added: January 15, 2026
Махачкала: ИПЦ ДГМУ, 2025.
В сборнике опубликованы доклады научной конференции, посвященные 80-летию Победы в Великой Отечественной войне. ...
Added: December 28, 2025
Sokolov B., Социология: методология, методы, математическое моделирование 2025 № 61 С. 7–76
This article reviews a set of estimands commonly used in modern applied research to operationalize causal inquiries within the Rubin Causal Model (RCM). I first introduce the basic average treatment effects (ATE, ATT, ATC) and then describe their main extensions, including local and conditional treatment effects, causal interactions, causal mediation, multivalued or continuous treatments, and ...
Added: December 19, 2025
Yanova M., Maltseva D., Tonevitsky A., Frontiers in Cell and Developmental Biology 2025 Vol. 13 Article 1720996
Colorectal cancer (CRC) remains one of the leading causes of cancer-related morbidity and mortality worldwide. Tumor sidedness, distinguishing left- (LCRC) and right-sided (RCRC) cancers, has emerged as a critical clinical determinant, influencing patient prognosis and therapeutic response. However, the cellular and molecular mechanisms underlying these differences remain poorly understood. Recent advances in single-cell RNA sequencing ...
Added: December 12, 2025