• A
  • A
  • A
  • АБВ
  • АБВ
  • АБВ
  • A
  • A
  • A
  • A
  • A
Обычная версия сайта
  • RU
  • EN
  • HSE University
  • Publications
  • Book chapter
  • Clonal T-cell repertoire analysis of patients with ankylosing spondylitis and HLA-B27+ healthy donors
  • RU
  • EN
Расширенный поиск
Высшая школа экономики
Национальный исследовательский университет
Priority areas
  • business informatics
  • economics
  • engineering science
  • humanitarian
  • IT and mathematics
  • law
  • management
  • mathematics
  • sociology
  • state and public administration
by year
  • 2027
  • 2026
  • 2025
  • 2024
  • 2023
  • 2022
  • 2021
  • 2020
  • 2019
  • 2018
  • 2017
  • 2016
  • 2015
  • 2014
  • 2013
  • 2012
  • 2011
  • 2010
  • 2009
  • 2008
  • 2007
  • 2006
  • 2005
  • 2004
  • 2003
  • 2002
  • 2001
  • 2000
  • 1999
  • 1998
  • 1997
  • 1996
  • 1995
  • 1994
  • 1993
  • 1992
  • 1991
  • 1990
  • 1989
  • 1988
  • 1987
  • 1986
  • 1985
  • 1984
  • 1983
  • 1982
  • 1981
  • 1980
  • 1979
  • 1978
  • 1977
  • 1976
  • 1975
  • 1974
  • 1973
  • 1972
  • 1971
  • 1970
  • 1969
  • 1968
  • 1967
  • 1966
  • 1965
  • 1964
  • 1963
  • 1958
  • More
Subject
News
April 28, 2026
Scientists Develop Algorithm for Accurate Financial Time Series Forecasting
Researchers at the HSE Faculty of Computer Science benchmarked more than 200,000 model configurations for predicting financial asset prices and realised volatility, showing that performance can be improved by filtering out noise at specific frequencies in advance. This technique increased accuracy in 65% of cases. The authors also developed their own algorithm, which achieves accuracy comparable to that of the best models while requiring less computational power. The study has been published in Applied Soft Computing.
April 27, 2026
Fair Division: How Mathematics Helps to Divide the Indivisible
How can items be allocated among participants so that no one feels short-changed? Alexander Karpov, Assistant Professor at the Faculty of Economic Sciences, and his Singaporean colleague, Prof. Warut Suksompong, set out to find a mathematical answer to this question. In this interview, they discuss how a model of rational preferences is constructed, why one cannot rely on a simple sum of values, and where an algorithm that asks a minimal number of questions can be useful.
April 24, 2026
Electronics of the Future: Why Superconductors and Spintronics Work Together
It was once believed that superconductivity and magnetism avoided each other like the devil avoids holy water. However, modern nanostructures prove the opposite. A Russian theoretical physicist and Indian experimentalists have joined forces to create the electronics of the future—free from energy losses. Nataliya Pugach, Professor at the School of Electronic Engineering at HSE MIEM and Leading Research Fellow at the Quantum Nanoelectronics Laboratory, explains how a long-standing acquaintance in Cambridge grew into a mirror laboratory project with the Indian Institute of Technology Bombay (IIT Bombay), how superconducting spintronics works, and what surprises a researcher in India beyond the university campus.

 

Have you spotted a typo?
Highlight it, click Ctrl+Enter and send us a message. Thank you for your help!

Publications
  • Books
  • Articles
  • Chapters of books
  • Working papers
  • Report a publication
  • Research at HSE

?

Clonal T-cell repertoire analysis of patients with ankylosing spondylitis and HLA-B27+ healthy donors

P. 119–119.
Komech E. A., Zvyagin I. V., Pogorelyy M. V., Nazarov V. I., Bochkova A. G., Mamedov I. Z., Lebedev Y. B.
Language: English
Keywords: bioinformaticsбиоинформатика

In book

Abstract Book of the 4th European Congress of Immunology
Вена: [б.и.], 2015.
Similar publications
Multimodal graph, surface, and language-based model for protein protein interaction prediction
Arteaga Moreano B. D., Chervov N., Poptsova M., Scientific Reports 2026 Vol. 16 No. 1 Article 4772
Accurate prediction of protein-protein interactions (PPIs) is fundamental to understanding biological processes and disease mechanisms. While deep learning offers a powerful alternative to costly experimental methods, existing approaches often overlook critical protein-surface information and rely on simplistic feature fusion techniques, thereby limiting performance. To address this, we introduce GSMFormer-PPI, a novel multimodal framework that integrates ...
Added: February 4, 2026
Prediction of protein-protein interactions using point transformer and spherical Convex Hull graphs
David Arteaga, Poptsova M., Computational and Structural Biotechnology Journal 2026 Vol. 31 P. 82–93
Accurate predictions and large-scale identification of protein-protein interactions (PPIs) are crucial for understanding their inherent biological mechanisms and protein functions in virtually all biological processes. Nowadays, graph-based deep learning models have made significant contributions in modeling proteins with physicochemical and geometric features. However, most of these models rely on conventional graph construction methods, such as ...
Added: December 22, 2025
Utilizing the VirIdAl Pipeline to Search for Viruses in the Metagenomic Data of Bat Samples
Budkina A., Korneenko E., Kotov I. et al., Viruses 2021 No. 10 P. 2006
According to various estimates, only a small percentage of existing viruses have been discovered, naturally much less being represented in the genomic databases. High-throughput sequencing technologies develop rapidly, empowering large-scale screening of various biological samples for the presence of pathogen-associated nucleotide sequences, but many organisms are yet to be attributed specific loci for identification. This ...
Added: September 19, 2025
Transcriptomic Maps of Colorectal Liver Metastasis: Machine Learning of Gene Activation Patterns and Epigenetic Trajectories in Support of Precision Medicine
KUDRYAVTSEVA A., Cancers 2023
Liver metastasis is a significant factor contributing to mortality associated with colorectal cancer. Establishing the biological mechanisms of metastasis is crucial for refining diagnostics and identifying therapeutic windows for interventions. Currently, little is known of the processes that govern the development of liver metastases, the role of the tumor microenvironment, the role of epigenetics, and ...
Added: July 1, 2025
Новая эра биоинформатики
Аксенова А. Ю., Жук А. С., Степченкова Е. И. et al., Экологическая генетика 2025 Т. 23 № 2 С. 1–14
Биоинформатика — это быстро развивающаяся дисциплина на стыке биологии, информатики и математики. Научно-технический прогресс в области биологических и биомедицинских наук за последние годы привел к стремительному росту объемов данных. Для анализа и интерпретации больших данных нужны мощные вычислительные инструменты и специалисты с глубокими знаниями в различных областях, включая молекулярную биологию, генетику, программирование и математику. В ...
Added: May 20, 2025
Genome-wide association studies of ischemic stroke based on interpretable machine learning
Stefan Nikolić, Ignatov D. I., Khvorykh G. et al., PeerJ Computer Science 2024 Vol. 10 Article e2454
Despite the identification of several dozen genetic loci associated with ischemic stroke (IS), the genetic bases of this disease remain largely unexplored. In this research we present the results of genome-wide association studies (GWAS) based on classical statistical testing and machine learning algorithms (logistic regression, gradient boosting on decision trees, and tabular deep learning model ...
Added: December 11, 2024
Proceedings of Science, volume 429. The 6th International Workshop on Deep Learning in Computational Physics
[б.и.], 2023.
The Workshop will be held in the Meshcheryakov Laboratory of Information Technologies (MLIT) of the Joint Institute for Nuclear Research (JINR) on July 6-8, 2022. The workshop primarily focuses on the use of machine learning in particle astrophysics and high energy physics, but is not limited to this area. Topics of interest are various applications of ...
Added: March 12, 2024
Unsupervised domain adaptation methods for cross-species transfer of regulatory code signals
Pavel Latyshev, Fedor Pavlov, Herbert A. et al., , in: Proceedings of 11th Moscow Conference on Computational Molecular Biology MCCMB'23.: IITP RAS, 2023.
Added: December 1, 2023
Proceedings of 11th Moscow Conference on Computational Molecular Biology MCCMB'23
IITP RAS, 2023.
В сборнике представлены тезисы работ участников 11-ой Московской конференции по вычислительной молекулярной биологии MCCMB'23. Работы посвящены актуальным вопросам анализа аминокислотных и нуклеотидных последовательностей, структур биополимеров, молекулярной эволюции, методов высокопроизводительного секвенирования, системной биологии и биоалгоритмов. ...
Added: November 30, 2023
10th International Conference, PReMI 2023, Kolkata, India, December 12–15, 2023, Proceedings. Pattern Recognition and Machine Intelligence. LNCS, volume 14301
Cham: Springer, 2023.
Added: November 29, 2023
Cross-Domain Limitations of Neural Models on Biomedical Relation Classification
Alimova I., Tutubalina E., Nikolenko S. I., IEEE Access 2022 Vol. 10 P. 1432–1439
Relation extraction (RE) aims to extract relational facts from plain text, which is essential to the biomedical research field with the rapid growth of biomedical literature and generally large volumes of biomedicine-related text coming from various sources. Numerous annotated corpora and state-of-the-art models have been introduced in the past five years. However, there are no ...
Added: April 10, 2023
Identification of key genes of the ccRCC subtype with poor prognosis
Grigory Andreevich Puzanov, Scientific Reports 2022 Vol. 12 No. 1 Article 14588
Clear cell renal carcinoma has been reported in many research studies as a rather heterogeneous disease. Identification of different subtypes and their molecular characteristics can help in choosing a more effective treatment and predicting a response to it. In this study, using multi-omics clustering of RNA-Seq data of patients with clear cell renal carcinoma from ...
Added: September 23, 2022
Proceedings of the 12th ACM Conference on Bioinformatics, Computational Biology, and Health Informatics
NY: Association for Computing Machinery (ACM), 2021.
Continuing the annual tradition, the conference focuses on interdisciplinary research linking computer science, mathematics, statistics, biology, bioinformatics, biomedical informatics, and health informatics. ...
Added: December 7, 2021
Characterisation of the Mouse Cerebellar Proteome in the GFAP-IL6 Model of Chronic Neuroinflammation
Asgarov R., Sen M. K., Meena M. et al., Cerebellum 2021 P. 1–21
GFAP-IL6 transgenic mice are characterised by astroglial and microglial activation predominantly in the cerebellum, hallmarks of many neuroinflammatory conditions. However, information available regarding the proteome profile associated with IL-6 overexpression in the mouse brain is limited. This study investigated the cerebellum proteome using a top-down proteomics approach using 2-dimensional gel electrophoresis followed by liquid chromatography-coupled ...
Added: November 15, 2021
Characterisation of the Mouse Cerebellar Proteome in the GFAP-IL6 Model of Chronic Neuroinflammation
Asgarov R., / Series PMID: 34324160 "PMID: 34324160". 2021.
GFAP-IL6 transgenic mice are characterised by astroglial and microglial activation predominantly in the cerebellum, hallmarks of many neuroinflammatory conditions. However, information available regarding the proteome profile associated with IL-6 overexpression in the mouse brain is limited. This study investigated the cerebellum proteome using a top-down proteomics approach using 2-dimensional gel electrophoresis followed by liquid chromatography-coupled ...
Added: November 6, 2021
MATHEMATICAL MODELING AND HIGH-PERFORMANCE COMPUTING IN BIOINFORMATICS, BIOMEDICINE AND BIOTECHNOLOGY (MM-HPC-BBB-2018). The 3rd International Symposium
Novosibirsk: Институт вычислительной математики и математической геофизики Сибирского отделения РАН, 2018.
Problems of mathematical modeling in biomedicine, direct and inverse problems of determining the parameters of biophysical processes with the help of computer simulations will be discussed. The second international conference MM-HPC-BBB-2018 will include the following research sections and meetings:– High-performance and distributed computing in biomedicine; – Applications of bioinformatics and systems biology; – Data mining ...
Added: September 24, 2021
Proceedings of the 26th Conference of Open Innovations Assosiation FRUCT
IEEE, 2020.
This proceeding includes the papers of the following topics: Bioinformatics, e-Health and Wellbeing Internet of Things and enabling technologies Smart Spaces, Linked Data and Semantic Web Big Data and Data Mining, Data Storage and Management Knowledge and Data Managements Systems Location Based Services: Navigation, Logistics, e-Tourism Context Awareness and Proactive Services Sensor Design, Ad-hoc and ...
Added: September 24, 2021
Two Cobalt Chelatase Subunits Can Be Generated from a Single chlD Gene via Programed Frameshifting
Antonov I., , in: Proceedings of 10th Moscow Conference on Computational Molecular Biology MCCMB'21.: M.: IITP RAS, 2021. Ch. 11.
Magnesium chelatase chlIDH and cobalt chelatase cobNST enzymes are required for biosynthesis of (bacterio)chlorophyll and cobalamin (vitamin B12), respectively. Each enzyme consists of large, medium, and small subunits. Structural and primary sequence similarities indicate common evolutionary origin of the corresponding subunits. It has been reported earlier that some of vitamin B12 synthesizing organisms utilized unusual ...
Added: September 10, 2021
Proceedings of 10th Moscow Conference on Computational Molecular Biology MCCMB'21
M.: IITP RAS, 2021.
10th Moscow Conference on Computational Molecular Biology MCCMB'21 ISBN 978-5-901158-32-6 ...
Added: September 10, 2021
  • About
  • About
  • Key Figures & Facts
  • Sustainability at HSE University
  • Faculties & Departments
  • International Partnerships
  • Faculty & Staff
  • HSE Buildings
  • HSE University for Persons with Disabilities
  • Public Enquiries
  • Studies
  • Admissions
  • Programme Catalogue
  • Undergraduate
  • Graduate
  • Exchange Programmes
  • Summer University
  • Summer Schools
  • Semester in Moscow
  • Business Internship
  • Research
  • International Laboratories
  • Research Centres
  • Research Projects
  • Monitoring Studies
  • Conferences & Seminars
  • Academic Jobs
  • Yasin (April) International Academic Conference on Economic and Social Development
  • Media & Resources
  • Publications by staff
  • HSE Journals
  • Publishing House
  • iq.hse.ru: commentary by HSE experts
  • Library
  • Economic & Social Data Archive
  • Video
  • HSE Repository of Socio-Economic Information
  • HSE1993–2026
  • Contacts
  • Copyright
  • Privacy Policy
  • Site Map
Edit