?
A novel method for multiplex protein biomarker analysis of human serum using quantitative MALDI mass spectrometry
Journal of Pharmaceutical and Biomedical Analysis. 2022. Vol. 210. Article 114575.
Taraskin A., Konstantin K. Semenov, Lozhkov A., Baranovskaya I., Protasov A., Ramsay E., Tyulin A.
In this work, we have extended our previously proposed approach for determining protein concentrations in human serum (using MALDI-TOF mass spectrometry) to include simultaneous analysis of several proteins associated with acute inflammation (alpha-2-macroglobulin, fetuin-A, serum amyloid A1). This technique can be used to diagnose systemic inflammation and provides results in 4–5 h. The developed approach was verified using standard immunological methods (ELISA). Samples from 87 individuals, in specific groups, were used for testing and validation: control; inflammatory soft tissue disease accompanied by sepsis; influenza A infection; or COVID-19. The feasibility of differentiating patient groups with the aforementioned conditions was analyzed using a combination of the inflammatory markers described. For fetuin-A and serum amyloid A1, diagnostically significant concentration ranges were established.
Stepanyants V., Долгов И. М., Хорошилов Г. С. et al., Труды Института системного программирования РАН 2026 Т. 38 № 3 С. 95–110
Highly automated and connected vehicles are gradually entering the market. Currently, solutions are being proposed that allow these technologies to be used for cooperative driving automation, which can significantly improve traffic safety. Such technologies and their software should be tested to ensure safety before being implemented in real systems. Verification and validation of vehicular control ...
Added: May 12, 2026
Pogodaeva S., Miletina O., Antipova N. et al., Cancers 2025 Vol. 17 No. 19 Article 3228
Pediatric tumors such as neuroblastoma are characterized by a genome-wide ‘transcriptional burden’, surmising the involvement of multiple alterations of gene expression. Search for master regulators of transcription whose inactivation is lethal for tumor cells identified the non-POU domain-containing octamer-binding protein (NONO), a member of the Drosophila Behavior/Human Splicing family known for the ability to form ...
Added: April 15, 2026
Chernov K. V., Savin A. M., Otvodnikova D. E. et al., Oncology Research 2026 Vol. 34 No. 5 P. 1–40
The formation of drug resistance poses the ultimate threat in modern oncology. Targeted therapy lacks versatility, while conventional therapy is famous for its side effects. However, for the new therapeutics to address the challenge of drug resistance, such compounds should combine properties of both modalities. In this review, we argue that metal-based therapeutics are paramount ...
Added: April 15, 2026
Barskaya E. S., Savin A. M., Chernov K. V. et al., International Journal of Molecular Sciences 2026 Vol. 27 No. 6 Article 2800
Copper–organic compounds are being investigated as antitumor candidates. Besides their efficacy as cytotoxic agents alone, the oxidative potential of electrochemical Cu2+-to-Cu1+ transition emerges as an attractive approach for elimination of tumor cells otherwise resistant to chemotherapy. To minimize side effects of the potent oxidative burst upon Cu(II) reduction, the metal cations should be delivered to the ...
Added: April 15, 2026
S. V. Nikulin, Olkhovik D., A.V. Razumovskaya et al., Doklady Biochemistry and Biophysics 2026
A novel trend in anticancer therapy is based on the combination of cytotoxic and metabolic drugs. Bach1 is a transcription factor activating glycolysis and increasing proliferation and metastatic potential in cancer cells. The cytotoxic effect was evaluated for a combination of rotenone, an inhibitor of mitochondrial respiration, and two different inhibitors of Bach1 transcription factor ...
Added: April 13, 2026
Kuvshinov A., Fominykh A., Ivanov F., IEEE Access 2026 Vol. 14 P. 50549–50557
The recursive (U|U+V) construction, a generalization of which includes polar codes, provides a powerful framework for building complex codes from simpler components. However, existing approaches predominantly rely on fixed or symmetric tree architectures, overlooking the critical impact of decomposition choice on code performance. This paper addresses the challenge of optimal tree decomposition selection by presenting a framework ...
Added: April 7, 2026
Manohin A., Электрооборудование: эксплуатация и ремонт 2026 № 2 С. 75–85
An extended method for calculating heat transfer coefficients using programs
for automated analysis of the thermal regime of TRIANA (ASONIKA-T) radio-electronic
equipment for various designs is proposed. Based on the analysis of the obtained
heat transfer coefficients, it is shown how to set realistic values for the convective
heat transfer coefficient in SOLIDWORKS Simulation and other CAE thermal analysis
systems. ...
Added: April 3, 2026
Zolotova N., Kirillova M., Dzhalilova D. et al., International Journal of Molecular Sciences 2025 Vol. 26 No. 23 Article 11511
Recently, evidence indicating that microplastics (MPs) have a hazardous effect on human health is accumulating. The potential of MPs having a role in carcinogenesis was suggested. Therefore, the aim of this study was to evaluate MPs’ effect on colitis-associated colorectal cancer (CAC) development. The AOM/DSS-induced CAC model was reproduced in two groups of adult male ...
Added: March 24, 2026
Silina M., Dzhalilova D., Fokichev N. et al., Frontiers in Molecular Biosciences 2025 Vol. 12 Article 1674608
Humans and laboratory animals differ in their resistance to hypoxia, which affects the severity of inflammatory diseases and the rate of tumor progression. Therefore, it is necessary to search for methods for assessing the initial tolerance to oxygen deficiency and the risks of developing acute mountain sickness without direct hypoxia exposure on the organism. The ...
Added: March 24, 2026
SciTePress, 2024.
This book contains the proceedings of the 21st International Conference on Informatics in Control, Automation and Robotics. This year, ICINCO is held in Porto, Portugal, on November 18-20, 2024. It was sponsored by the Institute for Systems and Technologies of Information, Control and Communication (INSTICC), and technically co-sponsored by the IEEE Systems, Man and Cybernetics ...
Added: March 17, 2026
IEEE, 2025.
On behalf of the organizing committee, it is our great privilege to present this compendium of research
articles for the 11th International Conference on Automation, Robotics, and Applications (ICARA 2025),
which will be held in the vibrant city of Zagreb, Croatia from February 12 to 14, 2025. The proceedings
encapsulate the latest advancements and innovative research in the ...
Added: March 17, 2026
Cham: Springer, 2026.
This book delivers actionable insights through 21 peer-reviewed chapters featuring new methods, models, and applications based on computational intelligence. Discover cutting-edge tools to support smart, efficient decision-making in complex, real-world scenarios. Organized into three parts—prescriptive analytics, soft computing models, and practical case studies—it spans domains such as healthcare, energy, mobility, finance, and public services. Readers ...
Added: March 17, 2026
Frolov O. V., Safin R. N., Tsoy T. G. et al., Ученые записки Казанского университета. Серия: Физико-математические науки 2025 Vol. 167 No. 4 P. 786–805
Advancements in robotics have expanded a use of unmanned aerial vehicle (UAV) swarms in
critical tasks such as disaster response, including search and rescue operations during floods, hurricanes,
landsliding, and earthquakes. Swarm formation control stands as a critical challenge in UAV swarm
control. In this article, a simple and resource-efficient method for addressing collisions within swarm
formations during outdoor ...
Added: March 17, 2026
Springer, 2026.
The two volume set LNAI 16303 + 16304 constitutes the refereed proceedings of the 10th International Conference on Interactive Collaborative Robotics, ICR 2025, held in Hanoi, Vietnam, during November 10–13, 2025. The 58 full papers presented in these two volumes were carefully reviewed and selected from 143 submissions. The papers are organized in the following topical sections:
Part ...
Added: March 17, 2026
Springer, 2026.
This book includes selected papers from the Fifth International Conference on Agriculture Digitalization and Organic Production (ADOP 2025), held in Barnaul, Altai Region, Russia, during June 03-06, 2025. The topics covered in the book are ground robotic systems in crop production, unmanned aerial vehicles in crop production, aerospace monitoring tools in crop production, robotic animal ...
Added: March 17, 2026
Song J., Bai Y., Svinin M. et al., Artificial Life and Robotics 2026 P. 1–13
This study introduces an innovative control approach for deploying multiple unmanned aerial vehicles (UAVs) to monitor an unknown food region. The proposed strategy is designed to optimally distribute UAVs across the food-afected area while cooperatively estimating the extent of inundation. To achieve this, an adaptive coverage controller is developed based on Centroidal Voronoi Tessellation (CVT), incorporating a novel ...
Added: March 17, 2026
Shchetinin I., Nikolenko P., Nizamov T. et al., Ceramics International 2026 Vol. 52 No. 3 P. 3500–3511
In this work, we comprehensively investigated the influence of Indium doping on the structure, magnetic and functional properties of strontium M-type hexaferrites SrFe12-xInxO19 nanoparticles (where x = 1.7, 1.8, 2.0). Colloidally stable SrFe12-xInxO19 nanoparticles (∼10 nm) were synthesized using a combination of the citrate method and high-energy ball milling. We demonstrate that doping reduces both the specific saturation magnetization and, ...
Added: March 16, 2026
Kurtc V., Prokhorov A., Journal of Mathematical Sciences 2025 No. 295 P. 229–240
We present a methodology for calibrating doubly constrained gravity models. Three types of deterrence functions are examined: exponential, power, and combined. The latter includes two calibration parameters, whereas the others contain only one. The parameters are identified so that the model reproduces the observed trip length distribution with high accuracy. We test four optimization methods: ...
Added: March 12, 2026
Kiselev G., Prokhorov A., Journal of Mathematical Sciences. Vol. 295, No. 2, December, 2025. Mathematical Modeling and AI for Traffic Flows on Networks and Related Topics 2025 No. 295 P. 185–196
We study the problem of estimating the population and workplaces in a given area using open data sources and machine learning algorithms for automation and improvement of quality and accuracy of the transport demand calculation in transport modeling.
Bibliography: 6 titles. Illustrations: 7 figures. ...
Added: March 12, 2026