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Regular version of the site

Book chapter

Subgroup Discovery for Treatment Optimization

P. 48-53.

Modern medicine aspire to improve the effectiveness of treatment for some diseases through, so called, personalized medicine. However, totally personalized medicine or personalized treatment of even one disease is a very ambitious goal. Subgroup analysis of patients is a preliminary step to the total personalization. Several completely different views on the principles and usefulness of subgroup analysis for treatment personalization exist. This paper is limited to data-driven subgroup discovery, when collected data analyzed for significant treatment-biomarker interactions in post-hoc manner, and presents a brief overview of key methods for this type of subgroup analysis.

In book

Subgroup Discovery for Treatment Optimization
Edited by: J. Baixeries, S. Boytcheva, O. Pianykh et al. Iss. 6. EasyChair, 2018.