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  • Выбор терапии онкологического заболевания в подгруппах пациентов на основе анализа замкнутых описаний
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October 1, 2026
HSE Researchers Show How Congenital Motor Disorders Affect Brain Development
Researchers from HSE University’s Institute for Cognitive Neuroscience have synthesised the findings of their previous studies on brain development in children with obstetric brachial plexus palsy and arthrogryposis. Their analysis shows that impaired motor function in early childhood not only limits children’s motor experience but also affects memory, categorical thinking, and information processing. The study has been published in Frontiers in Psychology.
October 1, 2026
Window into the Body: Scientists Develop Neural Network to Detect Risk of 15 Diseases from Retinal Images
Russian universities, with the participation of HSE University, Sber, and Z-union, have developed a neural network that can simultaneously assess the risk of 15 types of pathology from retinal photographs, including not only eye diseases but also cardiovascular conditions. The AI system can help clinicians detect potentially concerning changes at an early stage, identify signs reflecting the condition of retinal blood vessels, and determine whether a patient may need further examination. The paper has been published in Frontiers in Medicine.
September 30, 2026
'We Did Not Limit the Time for Questions'
The International Laboratory for Supercomputer Atomistic Modelling and Multi-Scale Analysis at HSE University held a major conference on molecular dynamics. Participants had the opportunity to attend all the presentations, while speakers were given as much time as they needed to answer questions. The HSE News Service interviewed Grigory Smirnov, Head of the Laboratory, and Genri Norman, Chief Research Fellow, about the conference preparations and the discussions it generated.

 

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Выбор терапии онкологического заболевания в подгруппах пациентов на основе анализа замкнутых описаний

С. 352–359.
Korepanova N., Kuznetsov S.

The main tools of modern evidence-based medicine in comparing different treatments of lethal diseases are statistical criteria applied to results of randomized studies. However, important information is often lost in this kind of studies. In this paper we propose an approach to treatment selection in subgroups of patients given by similarity of their physiological and clinical descriptions. This similarity is naturally described by closed descriptions in terms of so called pattern structures. 

Language: Russian
Full text
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Keywords: subgroup analysisclosed descriptionsвыбор терапиианализ подгруппзамкнутые описания
Publication based on the results of:
Mining Data with Complex Structure and Semantic Technologies (2016)

In book

Пятнадцатая национальная конференция по искусственному интеллекту с международным участием КИИ-2016 (3-7 октября 2016г., г.Смоленск, Россия): Труды конференции
Т. 1. , Смоленск: Универсум, 2016.
Similar publications
Subgroup Discovery for Treatment Optimization
Korepanova N., , in: Proceedings of the first Workshop on Data Analysis in Medicine (WDAM-2017)Issue 6.: EasyChair, 2018. P. 48–53.
Modern medicine aspire to improve the effectiveness of treatment for some diseases through, so called, personalized medicine. However, totally personalized medicine or personalized treatment of even one disease is a very ambitious goal. Subgroup analysis of patients is a preliminary step to the total personalization. Several completely different views on the principles and usefulness of ...
Added: June 9, 2018
Машинное обучение для оптимизации лечения в подгруппах пациентов
Korepanova N., Искусственный интеллект и принятие решений 2018 № 1 С. 54–66
In clinical trials comparing experimental and control treatment the effect of treatment often depends on the range of patient’s characteristics (biomarkers) such as clinical, anthropological, genetic, psychological, social characteristics and others. Personalized medicine aims at finding such dependencies to tailor treatment strategies to a patient. This paper presents an overview of the approaches to data ...
Added: November 29, 2017
Pattern Structures for Treatment Optimization
Natalia V. Korepanova, Sergei O. Kuznetsov, , in: CLA 2016: Proceedings of the Thirteenth International Conference on Concept Lattices and Their Applications. CEUR Workshop ProceedingsVol. 1624.: M.: Higher School of Economics, National Research University, 2016. P. 217–229.
A comparison of different treatment strategies does not always result in determining the best one for all patients, one needs to study subgroups of patients with significant difference in efficiency between treatment strategies. To solve this problem an approach to subgroups generation is proposed, where data are described in terms of a pattern structure and ...
Added: October 12, 2016
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