THE CURRENT STATE OF THE RUSSIAN OIL AND GAS INDUSTRY: учебное пособие (Допущено УМО)
Work-book «The current state of the Russian oil and gas industry» is offered for publication as a training aid for students qualified at the direction 131000 “Oil and gas engineering”. We have described the geology of hydrocarbons, in particular - the geology of heavy oil, unconventional resources of energy, etc. In this workbook there are also methods for the development of deposits of heavy oil and produce shale oil. Special attention was given to unconventional sources of hydrocarbons, exactly, gas hydrates and clayey shale. Novelty of work-book is presentation of oil and gas terminology to students from China. This work-book is published for the first time and will be very useful for self-study students of oil and gas disciplines, as well as oil and gas terms in Russian, English and Chinese. The manuscript is classified as «Approved by UMO on Higher Education in the field of applied geology as a work book for students enrolled in the direction 131000 “Oil and Gas Engineering”».
Many environmental stimuli present a quasi-rhythmic structure at different timescales that the brain needs to decompose and integrate. Cortical oscillations have been proposed as instruments of sensory de-multiplexing, i.e., the parallel processing of different frequency streams in sensory signals. Yet their causal role in such a process has never been demonstrated. Here, we used a neural microcircuit model to address whether coupled theta–gamma oscillations, as observed in human auditory cortex, could underpin the multiscale sensory analysis of speech. We show that, in continuous speech, theta oscillations can flexibly track the syllabic rhythm and temporally organize the phoneme-level response of gamma neurons into a code that enables syllable identification. The tracking of slow speech fluctuations by theta oscillations, and its coupling to gamma-spiking activity both appeared as critical features for accurate speech encoding. These results demonstrate that cortical oscillations can be a key instrument of speech de-multiplexing, parsing, and encoding.
The article analyses Russia’s policy response to developments in its mineral resources base (often perceived as an exploration crisis), with a focus on oil. The authors review and discuss trends in exploration (including its organization and efficiency), recent developments in its financing, and the reorganization of exploration activity. The evolution of Russia’s licensing system is presented, drawing attention to changes that have affected incentives, risks, and barriers to potential resource users, both Russian and foreign. Also identified are conflicts between the objectives of resource managers and broader political goals and interests.
The present article is devoted to a legal regulation of investments in gas industry of Russia. The author points attention of the scientist on it its perspectives in view of BRICS, on the possibilities that this form of cooperation can provide. The object of the article is the characterization of the actual legal regulation and of the investment climate in general. In the conclusion the author proposes the new approach for cooperation in the domain of the gas production in Russia.
Hypoxia of trophoblast cells is an important regulator of normal development of the placenta. However, some pathological states associated with hypoxia, e.g. preeclampsia, impair the functions of placental cells. Oxyquinoline derivative inhibits HIF-prolyl hydroxylase by stabilizing HIF-1 transcription complex, thus modeling cell response to hypoxia. In human choriocarcinoma cells BeWo b30 (trophoblast model), oxyquinoline increased the expression of a core hypoxia response genes along with up-regulation of NOS3, PDK1, and BNIP3 genes and down-regulation of the PPARGC1B gene. These changes in the expression profile attest to activation of the metabolic cell reprogramming mechanisms aimed at reducing oxygen consumption by enabling the switch from aerobic to anaerobic glucose metabolism and the respective decrease in number of mitochondria. The possibility of practical use of the therapeutic properties of oxyquinoline derivatives is discussed.