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The inconsistent effects of tDCS in rehabilitation and cognitive enhancement: sources of variability and paths to personalization
Frontiers in Human Neuroscience. 2026. Vol. 20. No. 0. Article 1817726.
Background/aims:
Transcranial direct current stimulation (tDCS) has emerged as a promising intervention in both rehabilitation and cognitive enhancement, yet its effects remain inconsistent across studies. This variability has raised questions about the underlying mechanisms influencing tDCS efficacy.
Methods:
In this review, we address the issue of the inconsistent effect of tDCS on motor and cognitive domains across studies in healthy individuals and those with neurodegenerative disorders. A review of literature in the field was conducted using PubMed and Google Scholar.
Results:
Research indicates that individual anatomical differences among subjects may contribute to the inconsistent outcomes observed, as variations in current density at targeted brain regions and genetic variations responsible for the stimulation effect. Understanding the factors that contribute to the inconsistent effects of tDCS will be essential for enhancing its application in clinical settings and maximizing its potential benefits in cognitive rehabilitation and enhancement.
Conclusion:
Future research should focus on optimizing tDCS parameters and exploring individualized approaches to treatment, taking into account the diverse responses observed in different populations.
Dadinova L., Petoukhov M., Mozhaev A. et al., Crystallography Reports 2026 Vol. 71 P. 52–58
Bacterial chromosomes are tightly packed in the cells due to interactions with specific nucleoid-associated proteins. Among them, the IHF protein draws attention due to its presumed influence on intracellular crystallization processes, leading to bacterial resistance to drugs. The crystal structure of the IHF heterodimer is known only in complex with a short DNA fragment, whereas ...
Added: August 6, 2026
Vasilieva E., Bultseva M. A., Trifonova A., Current Psychology 2026 Vol. 45 Article 1320
The current exploratory study aims to reveal identity gaps and interpersonal communication strategies used by Russians to overcome social identity crises. Based on previous research, we assume that many Russians who live both in Russia and abroad face ethnic and national identity threats and experience different social identity crises due to recent geopolitical events. This ...
Added: August 6, 2026
Ulgen H., Journal of International Students 2026 Vol. 16 No. 17 P. 283–312
This study reports a secondary analysis of phenomenologically informed, semistructured interviews with 15 Turkish undergraduate and graduate students at three universities in Moscow and examines how peer networks function beyond emotional buffering to support academic engagement and institutional navigation in Russian–medium higher education. Drawing on social support theory, communities of practice, and community cultural wealth ...
Added: August 5, 2026
Radygina A., Kulikova S., Herald of the Russian Academy of Sciences 2025 Vol. 95 No. 6 P. 963–970
Musical training has a significant impact on brain organization, leading to functional and structural
adaptations that enhance auditory, visual, motor, and cognitive processes. This study investigates how
extensive musical training shapes functional brain connectivity by comparing professional musicians and
non-musicians. Using EEG phase-locking value (PLV) analysis, we examined neural synchronization across
alpha, beta, and gamma frequency ranges during music ...
Added: August 5, 2026
Zolotareva A., Социальные науки и детство 2026 Т. 7 № 2 С. 66–77
Context and relevance. Early detection of anxiety and depression symptoms is a priority task for the child and adolescent mental health system. As Russian practice traditionally relies on separate instruments, assessing anxiety and depression in isolation, there is a need for integrated instruments. Objective. To examine the factor structure of the Russian version of the ...
Added: August 4, 2026
Iskakova B., Kleinlein E. V., Prisyazhniuk D. et al., European Journal of Education 2026 Vol. 61 No. 3 Article e70810
This study examines pre-service teachers' (PSTs) attitudes towards inclusive education in Germany and Russia and investigates how they relate to teacher training curricula and teacher educators' discourse. A mixed-methods design was used, including an online survey of PSTs (n = 460) with an open-ended question, curriculum review and exploratory interviews with university educators in both contexts. The ...
Added: August 3, 2026
Reznichenko S. I., Кияненко И. К., Nartova-Bochaver S. K. et al., Экспериментальная психология 2026 Т. 19 № 2 С. 10–28
Abstract
Context and relevance. In the context of accelerated urbanization and a growing disconnect from the natural
environment, there is increasing interest in biophilic attitudes — a system of stable views, beliefs, and
evaluations that reflect a person’s relationship with living nature and shape their psychological well-being and
environmentally responsible behavior. Existing tools for their measurement, such as the ...
Added: August 3, 2026
Mikhaylets E. V., Razorenova A. М., Chernyshev V. L. et al., Scientific Reports 2026 Vol. 16 Article 23560
Meditation offers a naturalistic paradigm for studying introspection, yet the neural dynamics of advanced tantric practices remain largely unexplored. Buddhist Highest Yoga Tantra (BHYT) comprises a sequence of eight dissolution stages culminating in the “clear light” state. We recorded EEG during eyes-closed BHYT meditation performed in monasteries and hermitages (51 sessions from 36 male practitioners; ...
Added: July 29, 2026
Hachaturova M. R., Safonova A., Экспериментальная психология 2026 Т. 19 № 2 С. 51–66
Context and relevance. The influence of the environment on psychological well-being has been studied in a wide variety of contexts, including workplaces, schools, healthcare facilities, and digital spaces. However, the psychological well-being of university faculty, particularly in relation to their connection to the university environment in the wide sense, remains virtually unrepresented in psychological research. ...
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Vasiliev F., Vasilieva E., Мир психологии. Научно-методический журнал 2026 Т. 2 № 125 С. 113–125
This study examines how various team aspects influence their evaluation
of teamwork outcomes. The research was conducted on a targeted sample in Russian
organizations. Using structural equation modeling, three groups of factors were identified:
team aspects that affected cognitive evaluation, emotional evaluation of work, and satisfaction
with the work process (team reputation and commitment); team aspects that did not ...
Added: July 22, 2026
Грудников Н. С., Пастухова Е. Г., Психология и право 2026 Т. 16 № 2 С. 198–214
Context and relevance. Mediation is a widespread form of conflict resolution with its own unique principles. Restorative justice, as a new paradigm in criminal justice, utilizes mediation as a form of implementation while adapting it to its own core concepts. Objective. The study aims to identify the differences between the value foundations of classical and ...
Added: July 22, 2026
Sokolova A., Журнал клинического и прикладного психоанализа 2024 Т. 1 С. 66–84
В статье рассматриваются взгляды нейропсихоанализа на этиологию расстройств зависимости от психоактивных веществ. Нейропсихоанализ исследует взаимосвязь между последними достижениями в нейронауках и психоаналитическими моделями сознания. Он пересматривает взгляды психоанализа на нарушения развития и функционирования человека на основе нового понимания работы головного мозга. Воззрения нейропсихоанализа на этиологию расстройств зависимости (РЗ) вырастают из аффективной нейронауки и семи эмоциональных ...
Added: July 18, 2026
Sokolova A., Psychoanalytic Psychology 2026
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Resistance to change remains central to psychoanalytic practice: Patients often maintain dysfunctional
beliefs and relational patterns even when they recognize their destructive nature. While psychoanalysis has
richly described resistance as a defense against painful affect and threats to internal object relations, the
process-level dynamics through which resistance persists over time have remained incompletely articulated.
This ...
Added: July 18, 2026
Shchebetenko S., / Series PsyArXiv "PsyArXiv". 2026.
Personality psychology owes much of its cumulative success to self- and informant-report
assessment. Report-based trait constructs are reliable, replicable, predictive, and useful for organising a
wide range of findings. This paper argues that their success should be understood not only
methodologically, but also theoretically. I propose the attributional model of personality reporting,
according to which self- and informant-reported traits are ...
Added: July 16, 2026
Arina Bukina, Eritsyan K., Antonova N. et al., Frontiers in Psychology 2026 Vol. 17 Article 1824428
Background:
Numerous studies have shown that indigenous populations experience poorer health outcomes compared to people with other backgrounds. However, the interpretation of these disparities remains challenging due to differences in living conditions and social environments, as well as by potential measurement-related biases. Little is known about whether the underlying mechanisms of mental health outcomes differ between ...
Added: July 15, 2026
Denisova V., Petrović N., Journal of Rational - Emotive and Cognitive - Behavior Therapy 2026 Vol. 44 No. 35 P. 1–16
Cognitive distortions are routinely described in cognitive-behavioral (CBT) and rational-emotive behavior (REBT) therapies as “errors in logic” or “illogical thinking.” While this terminology is pedagogically convenient, it often obscures a crucial conceptual distinction between violations of logical inference and problems related to the justification, scope, or evaluative force of belief content. In this paper, we do not ...
Added: July 15, 2026
Shmelev I., Мир психологии. Научно-методический журнал 2026 Т. 125 № 2 С. 269–287
The article is devoted to the study of subjectness phenomenon in higher education.
Subjectness is considered as a person’s ability for active creative actions, self-determination,
and transformation of reality. The main theoretical approaches to understanding subjectness
269in psychological and pedagogical discourse are analyzed. Techniques for developing students’
subjectivity are presented, including coaching, techniques for developing critical thinking,
dialogic learning, collaborative ...
Added: July 15, 2026
Qiwei G., Ruisi W., Zhongli L. et al., Journal of Affective Disorders 2026 Vol. 412 Article 122110
Subthreshold depression (StD) in adolescence is clinically important, but its neurobiological substrates remain unclear. We examined whether adolescents with StD show multimodal MRI alterations related to glymphatic function. ...
Added: July 13, 2026
Galina Oreshina, Journal of Nonverbal Behavior 2026 Article 10919
Interpersonal synchrony is increasingly conceptualized not as a static marker of rapport but as a dynamic, context-sensitive process that fluctuates across interactional phases to serve distinct relational functions. This study examined whether movement synchrony—absolute, non-absolute, client-leading, and counsellor-leading—was associated with therapeutic alliance in naturally occurring counselling sessions. Twenty-seven video recordings were analysed using motion energy ...
Added: July 13, 2026
Viktor Timokhov, Andrey Timashkov, Oksana Zinchenko, Scientific Reports 2025 Vol. 15 No. 1 Article 38153
This study investigated the causal role of the human frontopolar cortex (FPC) in managing counterfactual strategies during decision-making under uncertainty. Using a combination of cathodal high-definition transcranial direct current stimulation (HD-tDCS) and computational modeling, we examined how cathodal stimulation, preliminarily simulated with SimNIBS, affects the retrieval of alternative strategies in the task that constantly provokes ...
Added: October 1, 2025
Alexandra Bernadotte, Zinchenko O., Frontiers in Systems Neuroscience 2025 Vol. 19 Article 1444283
Attention deficit hyperactivity disorder (ADHD) stands as one of the most prevalent neurodevelopmental disorders, affecting millions worldwide. While traditional pharmacological interventions have been the cornerstone of ADHD treatment, emerging novel methods such as transcranial Direct Current Stimulation (tDCS) and neurofeedback offer promising avenues for addressing the multifaceted challenges of ADHD management. This review paper critically ...
Added: October 1, 2025
Перикова Е. И., Филиппова М. Г., Blagoveshchensky E. et al., International Journal of Psychophysiology 2021 Vol. 168 P. S89
Effects of transcranial direct current stimulation (tDCS) on acquisition of novel vocabulary remain controversial, which could be related to specific neural mechanisms underpinning different language learning strategies. To comprehensively assess tDCS effects on fast mapping (FM) and explicit encoding (EE) of novel words, we modulated tDCS stimulation regime (anodal/cathodal/sham), stimulated hemisphere (left/right), site (Broca/Wernicke/their right-hemispheric ...
Added: April 2, 2025
Sherbakova O., Блинова Е. Н., Новиковская Н. А. et al., В кн.: От слова - к репрезентации: нейрокогнитивные основы вербального научения.: СПб.: Скифия-принт, 2022. Гл. 5 С. 294–350.
Added: April 1, 2025
Перикова Е. И., Филиппова М. Г., Наследов А. Д. et al., В кн.: От слова - к репрезентации: нейрокогнитивные основы вербального научения.: СПб.: Скифия-принт, 2022. Гл. 2 С. 97–143.
This chapter describes the study on tDCS effects on explicit and implicit word learning ...
Added: April 1, 2025