Интерфейс мозг-компьютер: опыт построения, использования и возможные пути повышения рабочих характеристик
Brain-computer interfaces find application in a number of different areas and have the potential to be used for research as well as for practical purposes. The clinical use of BCI includes current studies on neurorehabilitation ([Frolov et al., 2013; Ang et al., 2010]), and there is the prospect of using BCI to restore movement and communication capabilities, providing alternative effective pathways to those that may be lost due to injury or illness. The processing of electrophysiological data requires analysis of high-dimensional, nonstationary, noisy signals reflecting complex underlying processes and structures. We have shown that for non-invasive neuroimaging methods such as EEG the potential improvement lies in the field of machine learning and involves designing data analysis algorithms that can model physiological and psychoemotional variability of the user. The development of such algorithms can be conducted in different ways, including the classical Bayesian paradigm as well as modern deep learning architectures. The interpretation of nonlinear decision rules implemented by multilayer structures would enable automatic and objective knowledge extraction from the neurocognitive experiments data. Despite the advantages of non-invasive neuroimaging methods, a radical increase in the bandwidth of the BCI communication channel and the use of this technology for the prosthesis control is possible only through invasive technologies. Electrocorticogram (ECoG) is the least invasive of such technologies, and in the final part of this work we demonstrate the possibility of using ECoG to decode the kinematic characteristics of the finger movement.
Increasing evidence suggests that neuronal communication is a defining property of functionally specialized brain networks and that it is implemented through synchronization between population activities of distinct brain areas. The detection of long-range coupling in electroencephalography (EEG) and magnetoencephalography (MEG) data using conventional metrics (such as coherence or phase-locking value) is by definition contaminated by spatial leakage. Methods such as imaginary coherence, phase-lag index or orthogonalized amplitude correlations tackle spatial leakage by ignoring zero-phase interactions. Although useful, these metrics will by construction lead to false negatives in cases where true zero-phase coupling exists in the data and will underestimate interactions with phase lags in the vicinity of zero. Yet, empirically observed neuronal synchrony in invasive recordings indicates that it is not uncommon to find zero or close-to-zero phase lag between the activity profiles of coupled neuronal assemblies. Here, we introduce a novel method that allows us to mitigate the undesired spatial leakage effects and detect zero and near zero phase interactions. To this end, we propose a projection operation that operates on sensor-space cross-spectrum and suppresses the spatial leakage contribution but retains the true zero-phase interaction component. We then solve the network estimation task as a source estimation problem defined in the product space of interacting source topographies. We show how this framework provides reliable interaction detection for all phase-lag values and we thus refer to the method as Phase Shift Invariant Imaging of Coherent Sources (PSIICOS). Realistic simulations demonstrate that PSIICOS has better detector characteristics than existing interaction metrics. Finally, we illustrate the performance of PSIICOS by applying it to real MEG dataset recorded during a standard mental rotation task. Taken together, using analytical derivations, data simulations and real brain data, this study presents a novel source-space MEG/EEG connectivity method that overcomes previous limitations and for the first time allows for the estimation of true zero-phase coupling via non-invasive electrophysiological recordings.
Autonomous taxies are in high demand for smart city scenario. Such taxies have a well specified path to travel. Therefore, these vehicles only required two important parameters. One is detection parameter and other is control parameter. Further, detection parameters require turn detection and obstacle detection. The control parameters contain steering control and speed control. In this paper a novel autonomous taxi model has been proposed for smart city scenario. Deep learning has been used to model the human driver capabilities for the autonomous taxi. A hierarchical Deep Neural Network (DNN) architecture has been utilized to train various driving aspects. In first level, the proposed DNN architecture classifies the straight and turning of road. A parallel DNN is used to detect obstacle at level one. In second level, the DNN discriminates the turning i.e. left or right for steering and speed controls. Two multi layered DNNs have been used on Nvidia Tesla K 40 GPU based system with Core i-7 processor. The mean squared error (MSE) for the detection parameters viz. speed and steering angle were 0.018 and 0.0248 percent, respectively, with 15 milli seconds of realtime response delay.
The performance of machine learning methods is heavily dependent on the choice of data representation (or features) on which they are applied. The rapidly developing field of representation learning is concerned with questions surrounding how we can best learn meaningful and useful representations of data. We take a broad view of the field and include topics such as deep learning and feature learning, metric learning, compositional modeling, structured prediction, reinforcement learning, and issues regarding large-scale learning and non-convex optimization. The range of domains to which these techniques apply is also very broad, from vision to speech recognition, text understanding, gaming, music, etc.
The Abstract book contains the abstracts of the posters presentations of the participants of the Methodological school: Methods of data processing in EEg and MEG, Moscow, 16-30th of April, 2013. The School was devoted to the theoretical and practical aspects of the contemporary methods of the dynamic mapping of brain activity by analysis of multichannel MEG and EEG.
The Abstract book contains the abstracts of the posters presentations of the participants of the Methodological school: Methods of data processing in EEG and MEG, Moscow, 16-30th of April, 2013. The School was devoted to the theoretical and practical aspects of the contemporary methods of the dynamic mapping of brain activity by analysis of multichannel MEG and EEG.
The general aim of this thesis is to explore the gendered and classed nature of social work and social welfare in Russia to show how social policy can be a part of and reinforce marginalisation. The overall research question is in what ways class and gender are constructed in Russian social work practice and welfare rhetoric through Soviet legacies and contemporary challenges? In addition, which actors contribute to the constitution of social work values and how this value system affects the agency of the clients? This study focuses on contradictory ideologies that are shaped in discursive formations of social policy, social work training and practice. It is a qualitative study, containing fi ve papers looking at this issue from three different perspectives: policy and institutions, culture and discourse, actors and identity. The data collection was arranged as a purposive–iterative process. The empirical material consists of qualitative interviews with social work practitioners, administrators and clients, participant observations in social services and analysis of documents of various kinds.
The distractive effects on attentional task performance in different paradigms are analyzed in this paper. I demonstrate how distractors may negatively affect (interference effect), positively (redundancy effect) or neutrally (null effect). Distractor effects described in literature are classified in accordance with their hypothetical source. The general rule of the theory is also introduced. It contains the formal prediction of the particular distractor effect, based on entropy and redundancy measures from the mathematical theory of communication (Shannon, 1948). Single- vs dual-process frameworks are considered for hypothetical mechanisms which underpin the distractor effects. Distractor profiles (DPs) are also introduced for the formalization and simple visualization of experimental data concerning the distractor effects. Typical shapes of DPs and their interpretations are discussed with examples from three frequently cited experiments. Finally, the paper introduces hierarchical hypothesis that states the level-fashion modulating interrelations between distractor effects of different classes.
This article describes the expierence of studying factors influencing the social well-being of educational migrants as mesured by means of a psychological well-being scale (A. Perrudet-Badoux, G.A. Mendelsohn, J.Chiche, 1988) previously adapted for Russian by M.V. Sokolova. A statistical analysis of the scale's reliability is performed. Trends in dynamics of subjective well-being are indentified on the basis the correlations analysis between the condbtbions of adaptation and its success rate, and potential mechanisms for developing subjective well-being among student migrants living in student hostels are described. Particular attention is paid to commuting as a factor of adaptation.
Hypoxia of trophoblast cells is an important regulator of normal development of the placenta. However, some pathological states associated with hypoxia, e.g. preeclampsia, impair the functions of placental cells. Oxyquinoline derivative inhibits HIF-prolyl hydroxylase by stabilizing HIF-1 transcription complex, thus modeling cell response to hypoxia. In human choriocarcinoma cells BeWo b30 (trophoblast model), oxyquinoline increased the expression of a core hypoxia response genes along with up-regulation of NOS3, PDK1, and BNIP3 genes and down-regulation of the PPARGC1B gene. These changes in the expression profile attest to activation of the metabolic cell reprogramming mechanisms aimed at reducing oxygen consumption by enabling the switch from aerobic to anaerobic glucose metabolism and the respective decrease in number of mitochondria. The possibility of practical use of the therapeutic properties of oxyquinoline derivatives is discussed.
I give the explicit formula for the (set-theoretical) system of Resultants of m+1 homogeneous polynomials in n+1 variables