Brain routes for reading in adults with and without autism: EMEG evidence
Reading utilises at least two neural pathways. The temporal lexical route visually maps whole words to their lexical entries, whilst the nonlexical route decodes words phonologically via parietal cortex. Readers typically employ the lexical route for familiar words, but poor comprehension plus precocity at mechanically 'sounding out' words suggests that differences might exist in autism. Combined MEG/EEG recordings of adults with autistic spectrum conditions (ASC) and controls while reading revealed preferential recruitment of temporal areas in controls and additional parietal recruitment in ASC. Furthermore, a lack of differences between semantic word categories was consistent with previous suggestion that people with ASC may lack a 'default' lexical-semantic processing mode. These results are discussed with reference to dual-route models of reading.
Increasing evidence suggests that neuronal communication is a defining property of functionally specialized brain networks and that it is implemented through synchronization between population activities of distinct brain areas. The detection of long-range coupling in electroencephalography (EEG) and magnetoencephalography (MEG) data using conventional metrics (such as coherence or phase-locking value) is by definition contaminated by spatial leakage. Methods such as imaginary coherence, phase-lag index or orthogonalized amplitude correlations tackle spatial leakage by ignoring zero-phase interactions. Although useful, these metrics will by construction lead to false negatives in cases where true zero-phase coupling exists in the data and will underestimate interactions with phase lags in the vicinity of zero. Yet, empirically observed neuronal synchrony in invasive recordings indicates that it is not uncommon to find zero or close-to-zero phase lag between the activity profiles of coupled neuronal assemblies. Here, we introduce a novel method that allows us to mitigate the undesired spatial leakage effects and detect zero and near zero phase interactions. To this end, we propose a projection operation that operates on sensor-space cross-spectrum and suppresses the spatial leakage contribution but retains the true zero-phase interaction component. We then solve the network estimation task as a source estimation problem defined in the product space of interacting source topographies. We show how this framework provides reliable interaction detection for all phase-lag values and we thus refer to the method as Phase Shift Invariant Imaging of Coherent Sources (PSIICOS). Realistic simulations demonstrate that PSIICOS has better detector characteristics than existing interaction metrics. Finally, we illustrate the performance of PSIICOS by applying it to real MEG dataset recorded during a standard mental rotation task. Taken together, using analytical derivations, data simulations and real brain data, this study presents a novel source-space MEG/EEG connectivity method that overcomes previous limitations and for the first time allows for the estimation of true zero-phase coupling via non-invasive electrophysiological recordings.
The collected papers contain articles by famous and young scientists on actual problems of philology (cognitive linguistics, lexical semantics, semiotics, pragmatics, text linguistics, stylistics; poetics, literary criticism; translation, intercultural communication). The issue also presents research on foreign language teaching methods. The edition is addressed to linguists, translators, teachers, postgraduates, students and a wide readership.
Topical issues on early childhood mental health are considered in the article. There is a high prevalence of psychiatric morbidity in early childhood and increase in mental disorders among children in general, which is ahead of a similar increase among adults. At the same time, unjustifiably on children’s mental health little attention is being paid, specialty “children’s psychiatrist” is not reestablished, the number of specialized beds is reduced etc. The data on the frowth of severe mental disorders (endogenous psychoses of the autism group) beginning in early and pre-school age.
The paper continues research into words denoting everyday life objects in the Russian language. This research is conducted for developing a new encyclopedic thesaurus of Russian everyday life terminology. Working on this project brings up linguistic material which leads to discovering new trends and phenomena not covered by the existing dictionaries. We discuss derivation models which gain polularity: clipped forms (komp < komp’juter ‘computer’, nout < noutbuk ‘notebook computer’, vel < velosiped ‘bicycle’, mot<motocikl ‘motorbike’), competing masculine and feminine con- tracted nouns derived from adjectival noun phrases (mobil’nik (m.) / mo- bilka (f.) < mobil’nyj telefon (m.) ‘mobile phone’, zarjadnik (m.) / zarjadka (f.) < zarjadnoe ustrojstvo (n.) ‘AC charger’), hybrid compounds (plat’e- sviter ‘sweater dress’, jubka-brjuki ‘skirt pants’, shapkosharf ‘scarf hat’, vilkolozhka ‘spork, foon’). These words vary in spelling and syntactic behav- iour. We describe a newly formed series of words denoted multifunctional objects: mfushkaZ< MFU < mnogofunkcional’noe ustrojstvo ‘MFD, multi- function device’, mul’titul ‘multitool’, centr ‘unit, set’. Explaining the need to compose frequency lists of word meanings rather than just words, we of- fer a technique for gathering such lists and provide a sample produced from our own data. We also analyze existing dictionaries and perform various experiments to study the changes in word meanings and their comparative importance for speakers. We believe that, apart from the practical usage for our lexicographic project, our results might prove interesting for research in the evolution of the Russian lexical system.
The Abstract book contains the abstracts of the posters presentations of the participants of the Methodological school: Methods of data processing in EEg and MEG, Moscow, 16-30th of April, 2013. The School was devoted to the theoretical and practical aspects of the contemporary methods of the dynamic mapping of brain activity by analysis of multichannel MEG and EEG.
The Abstract book contains the abstracts of the posters presentations of the participants of the Methodological school: Methods of data processing in EEG and MEG, Moscow, 16-30th of April, 2013. The School was devoted to the theoretical and practical aspects of the contemporary methods of the dynamic mapping of brain activity by analysis of multichannel MEG and EEG.
The article is implemented within the cognitive approach and is dedicated to the formation of a substantive core of the polysemantic verb, particularly of the verb of relations in the modern English. The first part of the article presents points of view on the semantic nature - "content plan" - of the word. In the second part of the paper the authors identify the main cognitive mechanisms underlying the formation of meanings of the verb compose, as well as its substantial core that combines all the lexical-semantic variants of a this verb.
The problem of non-invasive preoperative localization of motor areas in human cortex has not been solved yet. In clinical practice, localization of the hand representation in the primary motor cortex often becomes one of the main goals of the pre-surgical evaluation. In healthy subjects the area of the motor hand representation usually corresponds to certain standard anatomical landmarks (hand knob in the precentral gyrus), which can be easily found in sMRI images. Unfortunately, in patients with various brain lesions these landmarks may be absent or not corresponding to the area of the motor cortex. In such cases, location of irreplacable areas must be determined according to their functional and/or temporal dynamical characteristics.
It might become a promising method of localizing primary motor area by way of taking into account the characteristic properties of the primary motor cortex temporal dynamics during movement preparation.
The distractive effects on attentional task performance in different paradigms are analyzed in this paper. I demonstrate how distractors may negatively affect (interference effect), positively (redundancy effect) or neutrally (null effect). Distractor effects described in literature are classified in accordance with their hypothetical source. The general rule of the theory is also introduced. It contains the formal prediction of the particular distractor effect, based on entropy and redundancy measures from the mathematical theory of communication (Shannon, 1948). Single- vs dual-process frameworks are considered for hypothetical mechanisms which underpin the distractor effects. Distractor profiles (DPs) are also introduced for the formalization and simple visualization of experimental data concerning the distractor effects. Typical shapes of DPs and their interpretations are discussed with examples from three frequently cited experiments. Finally, the paper introduces hierarchical hypothesis that states the level-fashion modulating interrelations between distractor effects of different classes.
The article is devoted to a particular form of freedom of assembly — the right to counter-demonstrate. The author underlines the value of this right as an element of democratic society, but also acknowledges the risk of violent actions among participants of opposing demonstrations. Due to this risk, the government may adopt adequate measures restricting the right to counter-demonstrate, certain types of which are analyzed in this paper.
Development of standards of international controllability is reviewed in the article. Institutional approach is applied to development of international legal regime of Energy Charter. Definition of controllability is connected to development of international standards of dispute settlement, which are described in the article in detail. In connection with controllability, Russian interest, defense of investment in European Union and ecological investment encouragement, is reviewed in the article.
мировое управление и управляемость, Мировая экономика, международное экономическое право, энергетическая хартия, International control and controllability, International economics, international economic law, Energy Charter
международное частное право; недвижимость; ; школа бартолистов; бартолисты; теория статутов; статуарная теория/