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Commentary: Deep learning in obsessive-compulsive disorder: a narrative review
Frontiers in Psychiatry. 2026. Vol. 17. P. 1776019.
Kashevarova O., Portnova G., Khayrullina G., Liaukovich K., Proshina E., Gaidareva A., Verma R., Bhardwaj R., Martynova O.
Nersisyan A., Frontiers in Molecular Biosciences 2026 Vol. 13 Article 1995001
Antiviral activity is commonly summarized using endpoint measures such as EC50 or EC90, yet these quantities emerge from a dynamic biological system and depend on viral replication kinetics, host-cell properties, experimental design, and the assay used to quantify infection. Infectious-virus titers, viral RNA, infected-cell fractions, viability measurements, and immune readouts capture different components of the ...
Added: October 15, 2026
Тукачев Н. В., González-Jiménez M., Ramakrishnan G. et al., Physical Chemistry Chemical Physics 2021 Vol. 23 No. 23 P. 13250–13260
Low-frequency vibrations play an essential role in biomolecular processes involving DNA such as gene expression, charge transfer, drug intercalation, and DNA–protein recognition. However, understanding the vibrational basis of these mechanisms relies on theoretical models due to the lack of experimental evidence. Here we present the low-frequency vibrational spectra of G-quadruplexes (structures formed by four strands ...
Added: October 14, 2026
Батова О. Н., Савинецкая Л. Е., Проявка С. В. et al., Nature Conservation Research. Заповедная наука 2026 Т. 11 № 4 С. 25–39
Spermophilus suslicus is a threatened species listed in Red Data Books at all levels (from regional Red Data
Books to the IUCN Red List of Threatened Species), and it currently requires special conservation activity.
Over the past 30–50 years, its range has changed from continuous to mosaic, and its population has declined
everywhere. In 2015, in Russia experimental ...
Added: October 13, 2026
Temereva E., Zoologischer Anzeiger 2026 Vol. 325 P. 182–195
Brachiopoda is a group of animals, that is still insufficiently studied at the ultrastructural level, despite the significance of ultrastructure of tissues and organs for analysing the functional morphology, reconstructing the organisation and biology of numerous extinct brachiopods, and establishing relationships among major taxa. In the present study, we provide a revised reconstruction of the ...
Added: October 11, 2026
Ekaterina D. Riumina, Klink G. V., Alekseeva E. et al., PNAS, США 2026 Vol. 123 No. 35 P. 1–20
The role of escape from the cytotoxic T cell (CTL) response in SARS-CoV-2 evolution remains controversial. Here, we study the origin and spread of SARS-CoV-2 variants whose mutations reduce presentation by the HLA class I alleles common in human populations. We find that 35% of mutations that are characteristic of the variants of concern, and ...
Added: October 2, 2026
Aly Ismailov, Poptsova M., Plos One 2026 Vol. 21 No. 9 Article e0355902
Added: October 2, 2026
Knyazev E., Чеботарева О. Е., М.: Издательский дом НИУ ВШЭ, 2026.
This teaching and learning guide provides a concise overview of the theoretical and practical aspects of the basic skills required to work in a biological laboratory. It also includes protocols for practical classes conducted as part of the introductory professional training placement for first-year students in the Bachelor’s programme in Cell and Molecular Biotechnology at ...
Added: September 30, 2026
Ryskina H., Knyazev E., Вопросы биологической, медицинской и фармацевтической химии 2026 Т. 29 № 9 С. 84–91
Introduction. The active integration of rapidly developing omics and computer technologies in the 21st century has led to a breakthrough in understanding the principles of the functioning of living systems. One of the dynamically developing integrative areas in biology is biological modeling. The fundamental paradigm has been the methodology that allows for the prediction of ...
Added: September 29, 2026
ARUTYUNOV G. P., TARLOVSKAYA E. I., POLYAKOV D. S. et al., Heliyon 2024 Vol. 10 No. 7 Article e28892
The aim of this study is to investigate the course of the acute period of COVID-19 and devise a prognostic scale for patients hospitalized.
Materials and methods
The ACTIV registry encompassed both male and female patients aged 18 years and above, who were diagnosed with COVID-19 and subsequently hospitalized. Between June 2020 and March 2021, a total ...
Added: September 28, 2026
Арутюнов Г. П., Тарловская Е. И., Батлук Т. И. et al., Российский кардиологический журнал 2025 Т. 30 № 10 С. 111–120
The use of beta-blockers (BB) plays a crucial role in the treatment of cardiovascular diseases. However, there are significant discrepancies with current guidelines in real-world practice. The main issues related to suboptimal dosing regimens and poor medication adherence reduce the effectiveness of therapy and worsen the prognosis of patients. Under the auspices of the Eurasian ...
Added: September 28, 2026
Арутюнов Г. П., Батлук Т. И., Башкинов Р. А. et al., Клиническая медицина 2025 Т. 103 № 4 С. 309–313
Recurrent Pericarditis (RP) is a significant medical issue despite advancements in modern cardiology. The management of patients with this condition is associated with several challenges due to the variety of clinical manifestations, difficulties in differential diagnosis, lack of standardized treatment protocols, and a high likelihood of recurrences. Furthermore, there is insufficient data in the literature ...
Added: September 28, 2026
Lin Z., Duan K., Wan R. et al., Advanced Science 2026 P. 1–13
Targeted protein degradation represents a promising therapeutic strategy, yet its broader application is often limited by the scarcity of usable E3 ligases. Glutathione peroxidase 4 (GPX4) is a key target for inducing ferroptosis, but achieving sustained and potent inhibition remains challenging with conventional enzymatic inhibitors. Herein, we report the first small‐molecule GPX4 degraders that incorporate ...
Added: September 26, 2026
Diachkova E., Nikulin D., Кубкин Я. В. et al., American Journal of Respiratory and Critical Care Medicine 2026 Vol. 212
Accurate classification of a patient with pulmonary hypertension (PH) into one of five groups is fundamental for appropriate disease management strategies. The time from disease onset to correct diagnosis is unacceptably long in many cases. Chronic thromboembolic pulmonary hypertension (CTEPH) develops as a consequence of venous thromboemboli, resulting in a more pronounced hereditary predisposition to ...
Added: September 23, 2026
Xu Y., Ryabov F., Alexandrov I. et al., USA 2026 Vol. 6 No. 8 Article 101324
Центромеры обеспечивают расхождение хромосом, однако организацию их хроматина в пределах повторяющейся альфа-сателлитной ДНК долгое время было трудно изучать. Для решения этой задачи мы создали гаплотип-разрешённые аннотации сателлитной ДНК для полной диплоидной сборки генома человека T2T-HG002. Затем с помощью метода направленного метилирования с секвенированием длинных прочтений (DiMeLo-seq) мы картировали центромерный белок A (CENP-A), модификацию H3K9me3 и ...
Added: September 23, 2026
Hebbar P., Ryabov F., Alexandrov I. et al., Cell 2026 Vol. 189 P. 4891–4908.e12
The common marmoset is a New World monkey widely used to study primate evolution and human disease. We present a telomere-to-telomere (T2T) reference assembly for the species, plus three near-T2T haplotypes. These resolve previously inaccessible regions, including the centromeres, sex chromosomes, subterminal satellites, acrocentric chromosomes, and the major histocompatibility complex (MHC). We find marmoset centromeres ...
Added: September 23, 2026
Shaitan A., Ke Y., Shutao C. et al., 2026 No. 24 Article 181
Background Therapeutic peptides exert pivotal effects in diverse biological processes, and have attracted significant interest in the field of biomedicine in recent years. However, most existing methods often fail to adequately capture the intricate interactions among amino acid residues and the contextual dependencies within peptide sequences, which hampers the extraction of deep semantic representations and ...
Added: September 18, 2026
Anton Rogachev, Sysoeva O., Frontiers in Systems Neuroscience 2025 Vol. 19 Article 1658243
Added: September 17, 2026
Liaukovich K., Panfilova E., Khayrullina G. et al., International Journal of Psychophysiology 2025 Vol. 207 P. 112475
Added: September 5, 2026
Liaukovich K., Bainbridge E., Khayrullina G. et al., Neuroscience and Behavioral Physiology 2026 Vol. 56 P. 10–19
Added: September 5, 2026
Белканов Е. А., Budnik R., Грекова Е. М. et al., М.: ООО "Сам полиграфист", 2026.
The commentary on Federal Law No. 243-FZ of July 26, 2026, "On Supporting the Development of Artificial Intelligence Technologies in the Russian Federation" was prepared by leading Russian scholars specializing in information (digital) law, including the legal aspects of artificial intelligence. It contains an article-by-article scientific and practical systematic analysis of the provisions of the ...
Added: September 5, 2026
Дейнеко А. Г., Право и государство: теория и практика 2025 № 9 С. 156–160
The research is devoted to the implementation and protection of fundamental human rights and freedoms in the context of the development of the entire complex of modern information technologies. The author's concept of improving the mechanisms for ensuring the implementation and protection of the main categories of individual rights and freedoms has been developed, and the basic ...
Added: September 4, 2026
Tyurkin M., Azamat A., Singh J., [б.и.], 2025.
n this chapter, we explore into the role of multistakeholder collaboration in propelling sustainable innovation for the digital circular economy. As the world transforms towards sustainable and resource-efficient systems, collaboration is key. The interplay between governments, businesses, academia, and civil society becomes crucial. Understanding what motivates the adoption of technologies like artificial intelligence (AI), blockchain, ...
Added: July 20, 2026
Springer, 2026.
The book presents the proceedings of the 13th International Conference on Frontiers of Intelligent Computing: Theory and Applications (FICTA 2024), held at Intelligent Systems Research Group (ISRG), London Metropolitan University, London, United Kingdom, during June 6–7, 2025. Researchers, scientists, engineers and practitioners exchange new ideas and experiences in the domain of intelligent computing theories with ...
Added: June 8, 2026
Fonotov A., Kosychev A., Управление наукой: теория и практика 2026 Т. 8 № 1 С. 12–31
The study compares the national artificial intelligence (AI) strategies of the United States, China and Russia, assessing their substantive completeness and governance logics. It employs a hybrid framework that combines governance approaches (anticipatory, reflexive, experimentalist and tentative) with a content analysis of the structures of the strategies. The results show that the United States relies ...
Added: June 4, 2026