Proteomics-based scoring of cellular response to stimuli for improved characterization of signaling pathway activity

Kazakova E.; Solovyeva E.; Levitsky L.; Bubis J.; Emekeeva D.; Antonets A.; Alexey A. Nazarov; Gorshkov M.; Tarasova I.

doi:10.1002/pmic.202200275

Публикации

?

Proteomics-based scoring of cellular response to stimuli for improved characterization of signaling pathway activity

Proteomics. 2023. Vol. 53. No. 5. Article 2200275.

Kazakova E., Solovyeva E., Levitsky L., Bubis J., Emekeeva D., Antonets A., Alexey A. Nazarov, Gorshkov M., Tarasova I.

Научное направление: Химия

Язык: английский

DOI

Ключевые слова: Proteomics cell viability drug response pathway activity

2,2-Diaryl-1,3,2-dioxaborines based on curcumin: synthesis, photophysical properties and preliminary biological studies

Nazarov Alexey A., Dudarova N., Zhidkova O. и др., Journal of Photochemistry and Photobiology A: Chemistry 2026 Vol. 483 Article 117654

Добавлено: 9 сентября 2026 г.

Degree-based topological co-indices for QSPR modelling of benzenoid hydrocarbons: a comparative computational study

Chemical Papers 2026

Добавлено: 8 сентября 2026 г.

Bridging experiment and molecular dynamics: Mefenamic acid confinement in nanocrystalline cellulose aerogels under scCO2 conditions

Гурина Д. Л., Fashchevsky K. A., Oparin R. D. и др., Surfaces and Interfaces 2026 Vol. 98 Article 110545

Добавлено: 8 сентября 2026 г.

Stress tensor of inhomogeneous flexible polymer chain solutions beyond the ground-state dominance approximation

Будков Ю. А., Journal of Chemical Physics 2026 Vol. 165 No. 9 Article 094902

Добавлено: 2 сентября 2026 г.

“-Ethylene” vs “-ethane”: How minor cation variations drive the self-assembly of structurally different supramolecular diiodine-halometalate hybrid complexes

Новиков А. С., Polyhedron 2026 Vol. 299 Article 118358

Two new supramolecular halometalate hybrid complexes, (H2bpen){[MCl5](I2)} (M = Sb(III) (1) and Bi(III) (2); bpen – 1,2-Bis(4-pyridyl)ethylene, have been prepared. Despite very close similarity of the nature of cations, they reveal significant structural difference from the (H2bpe){[MCl5](I2)} (bpe – 1,2-bis(4-pyridil)ethane) reported earlier. We discuss these features, along with thermal stability, optical properties as well as Raman spectra ...

Добавлено: 2 сентября 2026 г.

From Small Data to High Capacity: Symbolic Learning of Sodium-Ion Cathode Materials

Meng K., Васенко А. С., Чулков Е. В. и др., The Journal of Physical Chemistry Letters 2026 Vol. 17 No. 36 P. 10546–10554

Добавлено: 29 августа 2026 г.

Monometallic Ln3+ and heterometallic Ln3+–Cd2+ complexes based on pentafluorophenylacetic acid: efficient control of dimension and luminescent properties

Белоусов Ю. А., Кискин М. А., Сидорук А. В. и др., Australian Journal of Chemistry 2022 Vol. 75 No. 9 P. 572–580

Добавлено: 26 августа 2026 г.

Understanding the electric double layer at electrode–electrolyte interfaces, Part III: crystallographic-face dependence of silver capacitance in aqueous NaF solutions

Мазур Д. А., Petr E. Brandyshev, Doronin S. и др., Electrochimica Acta 2026 Vol. 577 Article 149729

Добавлено: 20 августа 2026 г.

Hall effect in electrolyte solutions: Self-consistent Debye–Hückel–Onsager theory

Будков Ю. А., Каликин Н. Н., Journal of Chemical Physics 2026 Vol. 165 Article 064506

Добавлено: 12 августа 2026 г.

Charge-controlled binding, alloy synergy, and the copper anomaly in Au–Ag–Cu dimers to clusters: DFT-derived design rules for targeted drug delivery

Obijiofor O., Alexander S. Novikov, New Journal of Chemistry 2026 Vol. 50 No. 33 P. 13931–13957

Добавлено: 12 августа 2026 г.

Surface-sulfonated Al₂O₃, CeO₂, and TiO₂ as functional fillers for Nafion-type gel polymer electrolytes for lithium metal batteries

Voropaeva D., S. Novikova, I. Stenina и др., Solid State Ionics 2026 Vol. 445 Article 117288

Добавлено: 30 июля 2026 г.

Long-range machine-learning potentials with environment-dependent charges enable predicting LO-TO splitting and dielectric constants

Korogod D., Shapeev A., Ivan S. Novikov, Physical Review B: Condensed Matter and Materials Physics 2026 Vol. 114 No. 2 Article 024104

Добавлено: 22 июля 2026 г.

A Way to Create Mn-Containing GdFe3(BO3)4 and the Dopant Effect on Its Magnetic Properties

Moshkina E., Molokeev M., Zolotov A. и др., Journal of Alloys and Compounds 2026 Vol. 1077 Article 189412

Добавлено: 29 июня 2026 г.

Incorporating Scientific Knowledge into Neural Network Density Functionals

Schneider M., Zaripov D., Dokin R. и др., Journal of Chemical Theory and Computation 2026 Vol. 22 No. 9 P. 4405–4414

Добавлено: 26 июня 2026 г.

Electrodeposition and electrochromic properties of hydrated mixed oxides MoxW1-xO3·2H2O films

Лауринавичюте В. К., Levin E. E., Mironkova A. A. и др., Surfaces and Interfaces 2026 Vol. 81 Article 108389

Добавлено: 24 июня 2026 г.

Impact of heat treatment on microstructure and mechanical properties of additively manufactured aluminum bronze

Filippova A. V., Yurchenko N. Y., Smirnov S. A. и др., Journal of Alloys and Compounds 2026 No. 1074 Article 189162

Добавлено: 12 июня 2026 г.

An integrative proteomics method identifies a regulator of translation during stem cell maintenance and differentiation

Sabatier P., Beusch C., Мальцева Д. В. и др., Nature Communications 2021 No. 12 Article 6558

Добавлено: 12 ноября 2021 г.

200+ Protein Concentrations in Healthy Human Blood Plasma: Targeted Quantitative SRM SIS Screening of Chromosomes 18, 13, Y, and the Mitochondrial Chromosome Encoded Proteome

Kopylov A., Ponomarenko E., Ilgisonis E. и др., Journal of Proteome Research 2019 Vol. 18 No. 1 P. 120–129

Добавлено: 7 октября 2019 г.

Brain Proteome of Drosophila melanogaster Is Enriched with Nuclear Proteins

Kuznetsova K., Ivanov M., Пятницкий М. А. и др., Biochemistry. Biokhimiia 2019 Vol. 84 No. 1 P. 71–78

Добавлено: 7 октября 2019 г.

The Size of the Human Proteome: The Width and Depth

Ponomarenko E., Poverennaya E., Ilgisonis E. и др., International Journal of Analytical Chemistry 2016 P. 1–6

Добавлено: 14 марта 2018 г.

Human aqueous humor proteome in cataract, glaucoma and pseudoexfoliation syndrome

Kliuchnikova A., Samokhina N., Ilina I. и др., Proteomics 2016 Vol. 16 No. 13 P. 1938–1946

Добавлено: 14 марта 2018 г.

Database searching in mass spectrometry based proteomics

Кертес-Фаркаш А., Myers M. P., Current Bioinformatics 2012 Vol. 7 No. 2 P. 221–230

Bottom-up proteomics (mass spectrometry analysis of peptides obtained by proteolysis and separated by liquid chromatography, (LCMS/MS)) is one of the most frequently used techniques for identifying and characterizing proteins in biological samples. A key element of the analysis is database searching when the mass spectra of the peptides are compared with a database of theoretically ...

Добавлено: 18 ноября 2015 г.

Precursor mass dependent filtering of mass spectra for proteomics analysis

Кертес-Фаркаш А., Myers M. P., Protein and peptide letters 2014 Vol. 21 No. 8 P. 858–863

Identification and elimination of noise peaks in mass spectra from large proteomics data streams simultaneously improves the accuracy of peptide identification and significantly decreases the size of the data. There are a number of peak filtering strategies that can achieve this goal. Here we present a simple algorithm wherein the number of highest intensity peaks ...

Добавлено: 18 ноября 2015 г.

Data preprocessing and filtering in mass spectrometry based proteomics

Кертес-Фаркаш А., Myers M. P., Current Bioinformatics 2012 Vol. 7 No. 2 P. 212–220

Mass spectrometry based proteomics analysis can produce many thousands of spectra in a single experiment, and much of this data, frequently greater than 50%, cannot be properly evaluated computationally. Therefore a number of strategies have been developed to aid the processing of mass spectra and typically focus on the identification and elimination of noise, which ...

Добавлено: 18 ноября 2015 г.