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September 7, 2026
Biologists Discover 'Molecular Fingerprint' of Preeclampsia
Researchers at HSE University employed a new method to model hypoxia in placental cells during pregnancies complicated by preeclampsia and identified molecular markers of tissue hypoxia. Since hypoxia is one of the key mechanisms underlying preeclampsia, these findings are important for a more accurate and timely diagnosis of the disease and for the development of effective treatment methods. The paper has been published in Placenta.
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Randomized Machine Learning Algorithms to Forecast the Evolution of Thermokarst Lakes Area in Permafrost Zones

Automation and Remote Control. 2023. Vol. 84. No. 1. P. 64–81.
Yu. A. Dubnov, A. Yu. Popkov, Polishchuk V. Y., Sokol E. S., Melnikov A. V., Polishchuk Y. M., Yu. S. Popkov

Randomized machine learning focuses on problems with considerable uncertainty in data and models. Machine learning algorithms are formulated in terms of a functional entropylinear programming problem. We adapt these algorithms to forecasting problems on an example of the evolution of thermokarst lakes area in permafrost zones. Thermokarst lakes generate methane, a greenhouse gas affecting climate change. We propose randomized machine learning procedures using dynamic regression models with random parameters and retrospective data (climatic parameters and remote sensing of the Earth’s surface). The randomized machine learning algorithm developed below estimates the probability density functions of model parameters and measurement noises. Randomized forecasting is implemented as algorithms transforming the optimal distributions into the corresponding random sequences (sampling algorithms). The randomized forecasting procedures and technologies are trained, tested, and then applied to forecast the evolution of thermokarst lakes area in Western Siberia.

Research target: Mathematics Computer Science
Language: English
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Keywords: информационная энтропиядистанционное зондированиеRemote Sensing information entropyrandomized forecastingthermokarst lakesрандомизированное машинное обучениерандомизированное прогнозирование randomized machine learning термокарстовые озера
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