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October 19, 2026
'Cultural Studies Seeks to Understand What Lies Beneath the Surface of Everyday Things'
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Examining the effects of transcranial direct current stimulation on human episodic memory with machine learning

Plos One. 2020. Vol. 15. No. 12. P. 1–15.
Petrovskaya A., Kirillov B., Asmolova A., Galli G., Feurra M., Medvedeva A.

We aimed to replicate a published effect of transcranial direct-current stimulation (tDCS) -induced recognition enhancement over the human ventrolateral prefrontal cortex [1] and analyze the data with machine learning. We investigated effects over an adjacent region, the dorsolateral PFC. We found weak or absent effects over the VLPFC and DLPFC. We conducted machine learning studies to examine the effects of semantic and phonetic features on memorization, which revealed no effect of VLPFC tDCS on the original dataset or the current data. The highest contributing factor to memory performance was individual differences in memory not explained by word features, tDCS group, or sample size, while semantic, phonetic, and orthographic word characteristics did not contribute significantly. To our knowledge,We aimed to replicate a published effect of transcranial direct-current stimulation (tDCS) - induced recognition enhancement over the human ventrolateral prefrontal cortex (VLPFC) and analyze the data with machine learning. We investigated effects over an adjacent region, the dorsolateral prefrontal cortex (DLPFC). In total, we analyzed data from 97 participants after exclusions. We found weak or absent effects over the VLPFC and DLPFC. We conducted machine learning studies to examine the effects of semantic and phonetic features on memorization, which revealed no effect of VLPFC tDCS on the original dataset or the current data. The highest contributing factor to memory performance was individual differencesin memory not explained by word features, tDCS group, or sample size, while
semantic, phonetic, and orthographic word characteristics did not contribute significantly. To our knowledge, this is the first tDCS study to investigate cognitive effects with machine learning, and future studies may benefit from studying physiological as well as cognitive effects with data-driven approaches and computational models.

Research target: Medical Technologies
Priority areas: humanitarian
Language: English
DOI
Text on another site
Keywords: machine learningtranscranial direct current stimulation episodic memory
Publication based on the results of:
Multidisciplinary investigation of neurocognitive brain processes using neurophysiological, behavioral and structural approaches (2020)
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