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Effects of Transcranial Alternating Current Stimulation on the Primary Motor Cortex by Online Combined Approach with Transcranial Magnetic Stimulation
Journal of Visualized Experiments. 2017. No. 127. P. 1–7.
Transcranial Alternating Current Stimulation (tACS) is a neuromodulatory technique able to act through sinusoidal electrical waveforms in a specific frequency and in turn modulate ongoing cortical oscillatory activity. This neurotool allows the establishment of a causal link between endogenous oscillatory activity and behavior. Most of the tACS studies have shown online effects of tACS. However, little is known about the underlying action mechanisms of this technique because of the AC-induced artifacts on Electroencephalography (EEG) signals. Here we show a unique approach to investigate online physiological frequency-specific effects of tACS of the primary motor cortex (M1) by using single pulse Transcranial Magnetic Stimulation (TMS) to probe cortical excitability changes. In our setup, the TMS coil is placed over the tACS electrode while Motor Evoked Potentials (MEPs) are collected to test the effects of the ongoing M1-tACS. So far, this approach has mainly been used to study the visual and motor systems. However, the current tACS-TMS setup can pave the way for future investigations of cognitive functions. Therefore, we provide a step-by-step manual and video guidelines for the procedure.
Publication based on the results of:
Medushevsky A. N., Liberal.ru 2026
The Liberal Mission Foundation continues to introduce readers to new concepts of democracy and relevant publications. This discussion focuses on the challenges facing democracy in the era of globalization, as addressed in two recent books: *The Backsliders: Why Leaders Undermine Their Own Democracies* by S.C. Stokes (2025) and *Critical Theories and the Postsocialist Challenge: Race, ...
Added: August 26, 2026
Medushevsky A. N., Вопросы теоретической экономики 2026 № 2 С. 146–164
It is generally accepted that the basis of social and legal stability in any society is a consensus on vir tue — the fundamental values of proper behavior, ways of maintaining and reproducing them. And, conversely, the destruction of this consensus is a sign of the loss of stability and divergence of positions of social ...
Added: August 26, 2026
Vlasenko D., Saranskaia I., Zakharov D., European Physical Journal: Special Topics 2026 P. 1–16
Hypergraphs provide a natural framework for representing neurophysiological interactions distributed across sets of sensors. A key methodological question is how hyperedges should be defined from frequency-resolved electroencephalography/magnetoencephalography (EEG/MEG) data. We demonstrate a construction strategy in which hyperedges are obtained from canonical coherence (caCOH), an extension of coherence that estimates coupling between multidimensional signal spaces. To ...
Added: August 18, 2026
Diachkova M., Lelik V., Dorofeeva S. et al., Language Resources and Evaluation 2026 Vol. 60 Article 68
This article presents the Russian Language-Monolingual corpus (RusLan-M, v.1.0), a longitudinal multimedia collection of early child speech from two Russian-speaking monolingual children: Tosya (ages 0;10–3;10, 246 recordings) and Yasha (ages 1;04–3;00, 42 recordings). The corpus consists of approximately 41 h (2,454 min.) of video recordings and 35,386 child utterances, available with transcriptions in the CHAT ...
Added: August 17, 2026
Ekaterina Vasilyeva, Trifonova A., Bultseva M. A., Current Psychology 2026 Vol. 45 Article 1320
The current exploratory study aims to reveal identity gaps and interpersonal communication strategies used by Russians to overcome social identity crises. Based on previous research, we assume that many Russians who live both in Russia and abroad face ethnic and national identity threats and experience different social identity crises due to recent geopolitical events. This ...
Added: August 6, 2026
Ulgen H., Journal of International Students 2026 Vol. 16 No. 17 P. 283–312
This study reports a secondary analysis of phenomenologically informed, semistructured interviews with 15 Turkish undergraduate and graduate students at three universities in Moscow and examines how peer networks function beyond emotional buffering to support academic engagement and institutional navigation in Russian–medium higher education. Drawing on social support theory, communities of practice, and community cultural wealth ...
Added: August 5, 2026
A. Radygina, S. Kulikova, Herald of the Russian Academy of Sciences 2025 Vol. 95 No. 6 P. 963–970
Musical training has a significant impact on brain organization, leading to functional and structural
adaptations that enhance auditory, visual, motor, and cognitive processes. This study investigates how
extensive musical training shapes functional brain connectivity by comparing professional musicians and
non-musicians. Using EEG phase-locking value (PLV) analysis, we examined neural synchronization across
alpha, beta, and gamma frequency ranges during music ...
Added: August 5, 2026
Zolotareva A., Социальные науки и детство 2026 Т. 7 № 2 С. 66–77
Context and relevance. Early detection of anxiety and depression symptoms is a priority task for the child and adolescent mental health system. As Russian practice traditionally relies on separate instruments, assessing anxiety and depression in isolation, there is a need for integrated instruments. Objective. To examine the factor structure of the Russian version of the ...
Added: August 4, 2026
Iskakova B., Kleinlein E. V., Prisyazhniuk D. et al., European Journal of Education 2026 Vol. 61 No. 3 Article e70810
This study examines pre-service teachers' (PSTs) attitudes towards inclusive education in Germany and Russia and investigates how they relate to teacher training curricula and teacher educators' discourse. A mixed-methods design was used, including an online survey of PSTs (n = 460) with an open-ended question, curriculum review and exploratory interviews with university educators in both contexts. The ...
Added: August 3, 2026
Reznichenko S. I., Кияненко И. К., Nartova-Bochaver S. K. et al., Экспериментальная психология 2026 Т. 19 № 2 С. 10–28
Abstract
Context and relevance. In the context of accelerated urbanization and a growing disconnect from the natural
environment, there is increasing interest in biophilic attitudes — a system of stable views, beliefs, and
evaluations that reflect a person’s relationship with living nature and shape their psychological well-being and
environmentally responsible behavior. Existing tools for their measurement, such as the ...
Added: August 3, 2026
Krivoshchekov V., Gulevich O., Frontiers In Social Psychology 2026 Vol. 4
Precarious manhood theory (PMT) explains men's compensatory responses to masculinity threats in domains such as affect, aggression, risk-taking, dominance, and social attitudes. While recent meta-analytic evidence suggests that masculinity threat has a small-to-medium average effect, recent preregistered replication work has failed to reproduce some influential masculinity-threat effects in a large representative sample, raising questions about ...
Added: July 28, 2026
Hachaturova M. R., Safonova A., Экспериментальная психология 2026 Т. 19 № 2 С. 51–66
Context and relevance. The influence of the environment on psychological well-being has been studied in a wide variety of contexts, including workplaces, schools, healthcare facilities, and digital spaces. However, the psychological well-being of university faculty, particularly in relation to their connection to the university environment in the wide sense, remains virtually unrepresented in psychological research. ...
Added: July 25, 2026
Davydova A., Sheronova J., Kosonogov V. et al., Journal of Visualized Experiments 2025 No. 226 Article e67500
Transcranial magnetic stimulation (TMS) is a powerful method for revealing causal links between specific brain regions and cognitive functions. While offline TMS has traditionally dominated cognitive neuroscience research, online repetitive TMS (rTMS) presents undoubted advantages, enabling stimulation concurrent with task performance. Leveraging advancements in this stimulation method, the study introduces a novel online rTMS protocol ...
Added: December 19, 2025
Volodina M., Ossadtchi A., Makarova M. et al., В кн.: Когнитивная наука в Москве: новые исследования. Материалы конференции 25 – 26 июня 2025.: М.: Буки Веди, 2025.
It is known that the motor cortex exhibits increased excitability during the systolic phase of the cardiac cycle (Al et al., 2023). Previous studies have shown that self-observation can enhance interoceptive sensitivity (Ainley et al., 2012). We hypothesized that visual stimuli enhancing bodily awareness could influence the relationship between the phase of the cardiac cycle and ...
Added: September 9, 2025
Makarova M., Некрасова Ю. Ю., Fedosov N. et al., Brain Stimulation 2025 Vol. 18 No. 1 P. 495
Сortico-spinal neuron excitability can be tracked using rhythmic oscillations whose phase plays a pivotal role in assessing the state of the pertinent neural network. Brain’s oscillatory activity can be non-invasively registered with electroencephalography (EEG) and magnetoencephalography (MEG). Using transcranial magnetic stimulation (TMS) contingent upon the parameters of the ongoing brain activity was shown to have numerous applications in both research and clinics. Despite the potential, the described closed-loop ...
Added: September 8, 2025
Carlos Nieto-Doval, Aynur Ragimova, Gleb Perevoznyuk et al., Scientific Reports 2025 Vol. 15 Article 23245
Motor resonance (MoR) refers to the automatic activation of motor circuits during action observation, reflecting an internal simulation of the observed movement. This phenomenon is thought to arise
from the activity of mirror neuron regions, which modulate primary motor cortex (M1) excitability via cortico-cortical pathways. MoR, which is believed to be involved in the mechanism underlying action understanding ...
Added: August 28, 2025
W. Joseph MacInnes, Zhozhikashvili N., Feurra M., , in: First International Conference, AIiH 2024, Swansea, UK, September 4–6, 2024, Proceedings, Part II. Artificial Intelligence in Healthcare. LNCS, volume 14976Vol. 14976.: Springer, 2024. P. 221–234.
Convolutional Neural Networks (CNNs) match human performance in many visual tasks like the classification of images, however they may not simulate the underlying biological processes. We implemented a CNN to try replicate results from an object inversion experiment with Transcranial Magnetic Stimulation (TMS). After training on upright faces, the CNN model went through three stages ...
Added: January 28, 2025
Zhuravleva A.A., Stupina E., Malyutina S.A., , in: Десятая международная конференция по когнитивной науке: Тезисы докладов. Пятигорск, 26–30 июня 2024 г.: Пятигорск: ОПиИД УНР ФГБОУ ВО «ПГУ», 2024. P. 117–118.
Novel word acquisition is crucial for both first language acquisition and foreign language learning. Most previous studies of its neural bases were conducted via neuroimaging methods, which can reveal correlational but not causal links between neural and cognitive processes. This paper is one of the first to study the effect of transcranial alternating current stimulation ...
Added: January 12, 2025
Aynur A. Ragimova, Carlos M. Nieto-Doval, Mikhail I. Salamatin et al., Psychology. Journal of the Higher School of Economics 2024 Vol. 21 No. 3 P. 439–455
Though the mirror neuron system (MNS) is studied in the scientific community, the influence of the body posture on the functioning of the MNS, as well as on the excitatory and inhibitory system of the brain, has not been revealed yet. In our study, we investigated the functioning of the MNS in case of head ...
Added: September 29, 2024
Астафьева Д. С., Власов Я. В., Стрельник А. И. et al., Нервно-мышечные болезни 2023 Т. 13 № 2 С. 20–30
По общемировым данным, нейропатическая боль встречается у 7 % населения и в 57-65 % случаев сопровождается коморбидной депрессией, что, в свою очередь, усугубляет течение болезни и ухудшает качество жизни пациентов. Ритмическая транскраниальная магнитная стимуляция (рТМС) представляет собой неинвазивный нефармакологический метод терапии депрессии, также способный помочь пациентам облегчить восприятие нейропатической боли. Представлен обзор результатов применения протоколов ...
Added: March 6, 2024
Fedosov N., Julia Nekrasova, Makarova M. et al., , in: 2023 IEEE Ural-Siberian Conference on Computational Technologies in Cognitive Science, Genomics and Biomedicine (CSGB), 28-30 Sept. 2023.: IEEE, 2023. P. 189–195.
The paper introduces a novel hardware-software complex for the low latency real time phase-dependent transcranial
magnetic stimulation (TMS) neurofeedback. The software with key elements implemented on the board of the EEGrecording device accurately tracks the sensorimotor rhythm phase with minimal time-delay and immediately sends the trigger to the TMS-device. An accurate phase estimation is achieved by ...
Added: December 7, 2023
A. G. Davydova, J. P. Sheronova, V. V. Kosonogov et al., Neuroscience and Behavioral Physiology 2023 Vol. 53 No. 2 P. 247–256
The theory of cognitive dissonance (CD) is tightly linked with studies of the process of making complex decisions. In particular, CD is manifest within the framework of the “free choice paradigm” consisting of reassessment of alternatives as a result of choosing between two similar alternatives via the motivation to reduce internal conflict. The mechanisms of ...
Added: April 18, 2023
Vlasov A., Kuzmina L. P., Petraikin A. V. et al., Brain Stimulation 2023 Vol. 16 No. 1 P. 278–278
Our goal was to evaluate genetic and gender differences in motor threshold (MT) using monophasic single pulse Transcranial Magnetic Stimulation (TMS).
Methods. In this pilot study, we used TMS over dominant primary motor cortex and recorded motor evoked potentials (MEP) from the contralateral which yielded a higher MT than other TMS methods. We applied the monophasic stimulation ...
Added: February 24, 2023
Rossi S., Santarnecchi E., Feurra M., Handbook of Clinical Neurology 2022 Vol. 184 P. 239–247
Recent technological advances in the field of noninvasive brain stimulation (NIBS) have allowed to interact with endogenous brain oscillatory activity, the main neural communication code of our brain, opening new scenarios for transient modifications of cognitive and behavioral performances: such a possibility can be capitalized both for research purposes in subjects healthy, as well as ...
Added: October 29, 2022