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Транскраниальная электрическая стимуляция постоянным током при болезни Паркинсона
Parkinson’s disease is one of the most common neurodegenerative pathologies manifested by progressive motor and cognitive-
affective disorders. In the context of global population aging, the prevalence of pathology continues to grow steadily, which
creates a significant medical and social burden on health care systems and determines the relevance of the search for new
therapeutic approaches. As an additional method of Parkinson’s disease treatment transcranial direct current stimulation (tDCS)
is used to reduce motor and non-motor manifestations. Randomized controlled trials, meta-analyses, and systematic reviews
have been conducted to evaluate the efficacy of tDCS in Parkinson’s disease. Clinical studies demonstrate the significant
potential of tDCS for the correction of motor impairments, with a focus on symptoms of hypokinesia, postural instability, gait
disturbances, and cognitive impairment, with the most pronounced positive changes in executive function and working memory.
Additionally, there is a positive effect on the affective sphere, manifested in a reliable reduction of depressive symptomatology
according to standardized assessment scales. In addition, there is strong evidence of a normalizing effect on sleep architec-
ture, including improvements in sleep duration and quality, which is of particular importance in patients with comorbid sleep disorders. Overall, tDCS represents a promising direction in the complex therapy of Parkinson’s disease, demonstrating a good
safety profile and a wide range of therapeutic effects. The greatest clinical efficacy is achieved when optimized stimulation
protocols are used in combination with other rehabilitation methods. Future research should focus on developing personalized
approaches and more thorough investigation of long-term effects.