Resting-state functional connectivity in deaf and hearing individuals and its link to executive processing

Neuropsychologia. 2023. Vol. 185. Article 108583.

Cardin V., Kremneva E., Komarova A., Vinogradova V., Davidenko T., Zmeykina E., Kopnin P., Iriskhanova K., Woll B.

Sensory experience shapes brain structure and function, and it is likely to influence the organisation of functional networks of the brain, including those involved in cognitive processing. Here we investigated the influence of early deafness on the organisation of resting-state networks of the brain and its relation to executive processing. We compared resting-state connectivity between deaf and hearing individuals across 18 functional networks and 400 ROIs. Our results showed significant group differences in connectivity between seeds of the auditory network and most large-scale networks of the brain, in particular the somatomotor and salience/ventral attention networks. When we investigated group differences in resting-state fMRI and their link to behavioural performance in executive function tasks (working memory, inhibition and switching), differences between groups were found in the connectivity of association networks of the brain, such as the salience/ventral attention and default-mode networks. These findings indicate that sensory experience influences not only the organisation of sensory networks, but that it also has a measurable impact on the organisation of association networks supporting cognitive processing. Overall, our findings suggest that different developmental pathways and functional organisation can support executive processing in the adult brain.

Keywords: Deafness, Resting state, auditory cortex, Executive function