Ion-Sensitive Three-Terminal Device as a Universal Hybrid Platform With TiO2 Nanowires on the Channel
Abstract—We developed a three-terminal ion-sensitive device (TTISD) as a proton (H+) and arsenic (As3+) sensor
for the detection of glucose and As(III) dissolved in water. The TTISD was fabricated using the e-beam evaporation
and glancing angle deposition (GLAD) technique. The TiO2 nanowires (NWs) were grown by GLAD on the conducting
nafion channel of the TTISD to immobilize the test specimens. Arsenic (As) contamination in drinking water is a burning issue as it’s a threat to human health beyond the safe limit of As(III) in drinking water (0.005mg/dL). Glucose concentration within the limit of 0–200 mg/dL in various body fluids, such as blood, sweat, and saliva is also a necessary parameter to monitor. Early detection of high As(III) concentration in water and regularmonitoring of glucose concentration in the human body are essential for human health and safety. This work presents a common nano-hybrid platform for the detection of low-concentration glucose (40–200 mg/dL) and highconcentration
arsenic (0.02–2 mg/dL) in drinking water. The device exhibits a rapid response time of 1 s, enabling real-time detection of glucose and As(III).