Pathological Upper Limb Synergies of Patients with Poststroke Hemiparesis

Neuroscience and Behavioral Physiology. 2018. Vol. 48. No. 7. P. 813–822.

Хижникова А. Е., Клочков А. С., Nazarova M., Черникова Л. А.

This review presents current data on possible mechanisms forming synergies in health, particularly at the
cortical level. The mechanisms of formation of pathological synergies, taking account of the anatomical
and physiological characteristics of the upper limbs and the hypothesis, that synergistic patterns are transformed
in patients with spastic hemiparesis are discussed. Current views of the pathophysiological bases
of the formation of pathological synergies based on neuroimaging and neurophysiological study data are
presented, along with a method for noninvasive stimulation of the brain. The question of the correction and
transformation of pathological synergies in rehabilitation practice is discussed. Particular attention is paid to
clinical and instrumented evaluation of synergies and the use of validated clinical scales and instrumented
methods such as video movement analysis, electromyography, magnetic and contactless tracking systems,
and virtual reality technologies.

Keywords: моторная кора, motor cortex, синергии, synergies

Publication based on the results of: Активное и пассивное декодирование нейрональных процессов при выполнении когнитивных и нейроэкономических задач (2017)