Transcranial alternating current stimulation modulates risky decision making in a frequency controlled experiment
In this study, we investigated the effect of transcranial alternating current stimulation (tACS) on decision making under risk and executive control in humans. Stimulation was delivered online at 5, 10, 20, and 40 Hz on the left and right DLPFC while subjects performed a modified risky decision making task. This task allowed subjects to voluntarily switch between risky and safe options associated with potential gains or losses while simultaneously measuring the cognitive control component (voluntary switching) of decision making. Our results revealed a frequency- and hemisphere-specific effect of 20Hz tACS delivered on the left DLPFC that significantly increased risk-taking. These results suggest a modulatory role of 20 Hz neural oscillations on the left DLPFC in risk-taking perhaps by activating the brain’s reward system.