Без выбросов и отходов. Вклад Олимпийских игр – 2012 в устойчивое развитие: уроки для России.
Many environmental stimuli present a quasi-rhythmic structure at different timescales that the brain needs to decompose and integrate. Cortical oscillations have been proposed as instruments of sensory de-multiplexing, i.e., the parallel processing of different frequency streams in sensory signals. Yet their causal role in such a process has never been demonstrated. Here, we used a neural microcircuit model to address whether coupled theta–gamma oscillations, as observed in human auditory cortex, could underpin the multiscale sensory analysis of speech. We show that, in continuous speech, theta oscillations can flexibly track the syllabic rhythm and temporally organize the phoneme-level response of gamma neurons into a code that enables syllable identification. The tracking of slow speech fluctuations by theta oscillations, and its coupling to gamma-spiking activity both appeared as critical features for accurate speech encoding. These results demonstrate that cortical oscillations can be a key instrument of speech de-multiplexing, parsing, and encoding.
The given study is devoted to the issues of searching the ways for adaptation to climate change, mitigation of its impact on the economy and population, as well as to the role of increasing energy efficiency in the economies of some countries of Eastern Europe, Caucasus and Central Asia (EECCA). It also relates to the issues of responding to negative trends and emerging challenges caused by climate change. The Report represents several case studies on the above topics implemented in Moldova, Tadjikistan, Kazakhstan, Azerbaijan and the Russian Federation by the network of regional enviuronmental centres. It also contains consideration of possible methodological approaches and recommendations on addressing the above issues in the EECCA region.
In the past decades Foresight has been significantly developed as a tool for long-term forecasting in the field of power generation and energy efficiency. Such research aims at investigation of the most promising innovation strategies in this area, identifying various (including alternative) ways to achieve technological and market goals with the participation of best qualified experts. Such Foresight method as Roadmapping is widespread in the world practice. It helps to shape complex and interrelated views on prospects of innovation development in specific areas of energy efficiency, it links R&D programmes with creation of technologies and products, as well as their subsequent commercialization. The paper provides an overview of the world Foresight experience aimed at creating vision of the future and building innovation strategies related to energy efficiency. Special attention is paid to the Russian research practice, in particular to different types of Foresight projects implemented by the specialists of State University - Higher School of Economics. The authors describe the results of main projects dedicated to shape the future of energy-efficient technologies and to develop of innovation strategies on their application.
One of the key advances in genome assembly that has led to a significant improvement in contig lengths has been improved algorithms for utilization of paired reads (mate-pairs). While in most assemblers, mate-pair information is used in a post-processing step, the recently proposed Paired de Bruijn Graph (PDBG) approach incorporates the mate-pair information directly in the assembly graph structure. However, the PDBG approach faces difficulties when the variation in the insert sizes is high. To address this problem, we first transform mate-pairs into edge-pair histograms that allow one to better estimate the distance between edges in the assembly graph that represent regions linked by multiple mate-pairs. Further, we combine the ideas of mate-pair transformation and PDBGs to construct new data structures for genome assembly: pathsets and pathset graphs.