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September 21, 2026
Researchers Develop Methodology to Assess the Quality of Legal Representation in Criminal Proceedings
Having a good defence attorney in criminal proceedings can largely determine whether a defendant retains their freedom, health and good name. Researchers at HSE University propose a method for predicting an attorney’s performance based on the outcomes of their previous cases. The methodology takes into account the severity of the charges, the complexity of the cases, and the most likely outcome, drawing on judicial statistics.
September 21, 2026
Algebra, Geometry, and AI: Russian and Vietnamese Mathematicians Discuss Current Research
A delegation of scientists from Hanoi visited the HSE Faculty of Computer Science and then took part in a Russian-Vietnamese conference in St Petersburg. The events were part of the three-year project ‘Flexibility and Computational Methods.’ Over the course of the project, the researchers have prepared joint publications and obtained new mathematical results.
September 18, 2026
When Pictures Hinder Understanding: Illustrations May Impede Learning of Abstract Ideas
Illustrations can help remember specific actions but do not always make abstract ideas easier to learn. Researchers from HSE University and Humboldt University compared how people learn from texts with different levels of abstractness. They found that participants remembered illustrations better and performed better on related tasks after reading a multimedia text about yoga asanas than after reading an abstract text about the Nash equilibrium. The findings could help improve the selection of illustrations for educational and informational materials. The study has been published in Learning and Instruction.

 

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Validation of an NMR-Spectroscopic Method for Authenticity Confirmation of Buserelin Acetate Pharmaceutical Substance

Pharmaceutical Chemistry Journal. 2018. No. 52. P. 159–165.
Kuz’mina N. E., Krylov V. I., Moiseev S. V., Deryabin A., Yashkir V. A., Merkulov V. A.

The specificity of different variants of an NMR spectroscopic method for authenticity confirmation of buserelin acetate drug substance was estimated by comparing PMR and 13C NMR spectra of buserelin acetate and [5-D-tyrosine]buserelin acetate in various solvents. Spectra of these diastereomers differed most if deuterated water was used as the solvent. Solvent and intramolecular non-bonded interactions influenced proton- exchange tautomerism in the L-histidine residue of the analyzed oligomers. The widths of 13C NMR resonances of this amino acid depended on the proton-exchange rate. The method based on 13C NMR spectroscopy (D2O solvent) was recommended for pharmacopoeial analysis.

Research target: Biology
Language: English
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DOI
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Keywords: specificityNMR spectroscopybuserelin acetateanalytical method validationimidazole proton tautomerism
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