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August 24, 2026
Researchers Develop Method for Direct Generation of Regulatory DNA
Researchers at HSE University have developed a model for generating promoters and enhancers—DNA sequences that regulate gene activity. The model works directly with DNA nucleotides, without first transforming them into a continuous numerical representation. This solution could be useful for applications in synthetic biology and gene therapy. The study results were presented at the ICLR 2026 Workshop ‘Generative AI in Genomics (Gen^2): Barriers and Frontiers.’
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HSE Scholar Presents Research on Postcards in Brazil and South Korea
Timur Khusyainov, Deputy Dean of theFaculty of Humanities atHSE University–Nizhny Novgorod, took part in two international conferences—the XVI World Congress of Rural Sociology in Porto Alegre, Brazil, and the 36th Annual Conference of the Alliance of Digital Humanities Organisations (DH2026) in Daejeon, South Korea. On his way to the conferences, the researcher also visited several other places, where he presented the experience of the Pochtovoe educational project.

 

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Beyond Vector Spaces: Compact Data Representation as Differentiable Weighted Graphs

P. 1–11.
Mazur D., Egiazarian V., Morozov S., Babenko A.

Learning useful representations is a key ingredient to the success of modern ma- chine learning. Currently, representation learning mostly relies on embedding data into Euclidean space. However, recent work has shown that data in some domains is better modeled by non-euclidean metric spaces, and inappropriate geometry can result in inferior performance. In this paper, we aim to eliminate the inductive bias imposed by the embedding space geometry. Namely, we propose to map data into more general non-vector metric spaces: a weighted graph with a shortest path distance. By design, such graphs can model arbitrary geometry with a proper configuration of edges and weights. Our main contribution is PRODIGE: a method that learns a weighted graph representation of data end-to-end by gradient descent. Greater generality and fewer model assumptions make PRODIGE more powerful than existing embedding-based approaches. We confirm the superiority of our method via extensive experiments on a wide range of tasks, including classification, compression, and collaborative filtering.

Language: English
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Keywords: Representation learning

In book

Advances in Neural Information Processing Systems 32 (NeurIPS 2019)
[б.и.], 2019.
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