Vaccine prophylaxis, diagnostics and genotypes of mumps (epidemic parotitis) virus

Importance Elevated low-density lipoprotein cholesterol (LDL-C) is a modifiable risk factor for cardiovascular disease, the leading cause of premature death worldwide. Assessing the LDL-C–related burden is critical for guiding prevention and treatment strategies. Objectives To estimate the global, regional, and national burden of ischemic heart disease and ischemic stroke attributable to elevated LDL-C (relative to 35-54 mg/dL) from ...

Added: August 4, 2026

Global, regional, and national burden of road injuries 1990–2023: a systematic analysis for the Global Burden of Disease Study 2023

Vlassov V., van der Lubbe S. C., Moberg M. E. et al., The Lancet Public Health 2026 P. 1–6

Background Road injuries are a leading cause of mortality and morbidity worldwide. Years of international efforts have aimed to strengthen policy engagement, including the 2020 UN General Assembly's proclamation of the Second Decade of Action for Road Safety (2021–30), targeting a 50% reduction in road traffic deaths and serious injuries by 2030. The aim of this ...

Added: July 25, 2026

Global, regional, and national burden of tuberculosis and multidrug-resistant tuberculosis by HIV status, 1990–2023: a systematic analysis for the Global Burden of Disease Study 2023

Ledesma J. R., Zhang M., Liew M. F. et al., The Lancet Infectious Diseases 2026 P. 1–12

Background Tuberculosis (TB) is the leading global cause of death from a single infectious agent. Recent reductions in global health funding have threatened TB control, making comprehensive assessment of TB, HIV-related TB, and drug-resistant TB burdens before these disruptions essential for shaping effective responses. The WHO End TB Strategy sets targets of a 95% reduction in ...

Added: July 7, 2026

Socioeconomic development, longevity and prevalence of obesity and overweight: The retrospective longitudinal analysis of international data

Liapin G., Vlassov V., DIALOGUES IN HEALTH 2026 Vol. 8 Article 100317

Objectives Due to the economic growth at the end of the 20th century, people in low-income countries live longer but still spend most of their income on food. These countries, as well as affluent countries, demonstrate a rising prevalence of obesity. The interplay of longevity and obesity at different levels of economic development is not clear. Methods We ...

Added: June 29, 2026

Global, regional, and national burden of breast cancer among females, 1990–2023, with forecasts to 2050: a systematic analysis for the Global Burden of Disease Study 2023

Bhangdia K., May M. L., Kocarnik J. M. et al., The Lancet Oncology 2026 Vol. 27 No. 3 P. 302–326

Background Breast cancer is a leading cause of mortality and morbidity among females worldwide. As part of the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2023, we provided an updated comprehensive assessment of the epidemiological trends, disease burden, and risk factors associated with breast cancer globally, regionally, and nationally from 1990 to 2023. Methods Breast ...

Added: March 6, 2026

Global, Regional, and National Burden of Cardiovascular Diseases and Risk Factors in 204 Countries and Territories, 1990-2023

Stark B., DeCleene N., Desai E. et al., Journal of the American College of Cardiology 2025 Vol. 86 No. 22 P. 2167–2243

Background: Cardiovascular diseases (CVDs) are the leading cause of mortality and are among the foremost causes of disability globally. CVD burden has continued to increase in most countries since 1990, with trends driven by changing exposures to harmful risk factors, population growth, and population aging. Objectives: We report estimates of global, national, and subnational CVD burden, including 18 ...

Added: December 7, 2025

Quantifying the fatal and non-fatal burden of disease associated with child growth failure, 2000–2023: a systematic analysis from the Global Burden of Disease Study 2023

Troeger C., Arndt M. B., Aalruz H. et al., The Lancet Child and Adolescent Health 2026 Vol. 10 No. 1 P. 22–38

Background Child growth failure (CGF), which includes underweight, wasting, and stunting, is among the factors most strongly associated with mortality and morbidity in children younger than 5 years worldwide. Poor height and bodyweight gain arise from a variety of biological and sociodemographic factors and are associated with increased vulnerability to infectious diseases. We used data ...

Added: December 6, 2025

Global burden of 292 causes of death in 204 countries and territories and 660 subnational locations, 1990–2023: a systematic analysis for the Global Burden of Disease Study 2023

Naghavi M., Kyu H. H., A B. et al., The Lancet 2025 Vol. 406 No. 10513 P. 1811–1872

Background Timely and comprehensive analyses of causes of death stratified by age, sex, and location are essential for shaping effective health policies aimed at reducing global mortality. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2023 provides cause-specific mortality estimates measured in counts, rates, and years of life lost (YLLs). GBD 2023 aimed ...

Added: October 15, 2025

Burden of 375 diseases and injuries, risk-attributable burden of 88 risk factors, and healthy life expectancy in 204 countries and territories, including 660 subnational locations, 1990–2023: a systematic analysis for the Global Burden of Disease Study 2023

Hay S. I., Ong K. L., Santomauro D. F. et al., The Lancet 2025 Vol. 406 No. 10513 P. 1873–1922

Background For more than three decades, the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) has provided a framework to quantify health loss due to diseases, injuries, and associated risk factors. This paper presents GBD 2023 findings on disease and injury burden and risk-attributable health loss, offering a global audit of the state of ...

Added: October 15, 2025

The global, regional, and national burden of cancer, 1990-2013;2023, with forecasts to 2050: a systematic analysis for the Global Burden of Disease Study 2023

Force L. M., Kocarnik J. M., May M. L. et al., The Lancet 2025 Vol. 406 No. 10512 P. 1565–1586

Background Cancer is a leading cause of death globally. Accurate cancer burden information is crucial for policy planning, but many countries do not have up-to-date cancer surveillance data. To inform global cancer-control efforts, we used the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2023 framework to generate and analyse estimates of cancer burden ...

Added: September 25, 2025

Obsession with fertility – a way to overdiagnosis

Vlassov V., BMJ Evidence-Based Medicine 2025 Vol. 30 P. A10–A11

World wide reduction of fertility below the threshold of substitution lead to the shrinkage of the populations, ageing of populations and multiple undesired consequences including the collapse of the pension systems. Countries with the large and underpopulated territory (Russia) and/or quick ageing and population reduction (China) share the pessimistic vision of the instability and vulnerability. ...

Added: September 22, 2025

Characterising acute and chronic care needs: insights from the Global Burden of Disease Study 2019

Anza-Ramirez C., Jaime Miranda J., Armocida B. et al., Nature Communications 2025 Vol. 16 Article 4235

Chronic care manages long-term, progressive conditions, while acute care addresses short-term conditions. Chronic conditions increasingly strain health systems, which are often unprepared for these demands. This study examines the burden of conditions requiring acute versus chronic care, including sequelae. Conditions and sequelae from the Global Burden of Diseases Study 2019 were classified into acute or ...

Added: July 14, 2025

Global, regional, and national prevalence of adult overweight and obesity, 1990–2021, with forecasts to 2050: a forecasting study for the Global Burden of Disease Study 2021

Ng M., Gakidou E., Lo J. et al., The Lancet 2025 Vol. 405 No. 10481 P. 813–838

Background Overweight and obesity is a global epidemic. Forecasting future trajectories of the epidemic is crucial for providing an evidence base for policy change. In this study, we examine the historical trends of the global, regional, and national prevalence of adult overweight and obesity from 1990 to 2021 and forecast the future trajectories to 2050. Methods Leveraging established ...

Added: March 9, 2025

Global, regional, and national prevalence of child and adolescent overweight and obesity, 1990–2021, with forecasts to 2050: a forecasting study for the Global Burden of Disease Study 2021

Kerr J. A., Cini K. I., Patton G. C. et al., The Lancet 2025 Vol. 405 No. 10481 P. 785–812

Background Despite the well documented consequences of obesity during childhood and adolescence and future risks of excess body mass on non-communicable diseases in adulthood, coordinated global action on excess body mass in early life is still insufficient. Inconsistent measurement and reporting are a barrier to specific targets, resource allocation, and interventions. In this Article we report ...

Added: March 7, 2025

Different phenotypic assessment of depression prevalence in Russian population: DSM-criteria vs HADS

Rukavishnikov G., Rakitko A., Kasyanov E. et al., European Psychiatry 2022 Vol. 65 No. S1 P. 556–556

Introduction Because of different phenotypic approaches, data on depression prevalence is variable and controversial. Objectives The aim was to evaluate the prevalence of different depressive phenotypes in the Russian population (DSM criteria based self-report vs HADS questionnaire). Methods The data was from the on-line survey of 5116 clients of Genotek Ltd. (males - 50,63%; age - Me=35 (Q1-30;Q3-42)). The survey ...

Added: March 4, 2025

Global, regional, and national progress towards the 2030 global nutrition targets and forecasts to 2050: a systematic analysis for the Global Burden of Disease Study 2021

Arndt M. B., Abate Y. H., Abbasi-Kangevari M. et al., The Lancet 2025 Vol. 404 No. 10471 P. 2543–2583

Background The six global nutrition targets (GNTs) related to low birthweight, exclusive breastfeeding, child growth (ie, wasting, stunting, and overweight), and anaemia among females of reproductive age were chosen by the World Health Assembly in 2012 as key indicators of maternal and child health, but there has yet to be a comprehensive report on progress for ...

Added: December 15, 2024

Association of Drugs for Sale on the Internet and Official Health Indicators: Darknet Parsing and Correlational Study

Soshnikov S., Bekker S., Idrisov B. et al., JMIR Formative Research 2024 Vol. 8 Article e56006

Background:Studying illicit drug circulation and its effects on population health is complicated due to the criminalization of trade and consumption. Illicit drug markets have evolved with IT, moving digital to the “darknet.” Previous research has analyzed darknet market listings and customer reviews. Research tools include public health surveys and medical reports but lack neutral data ...

Added: December 7, 2024

Global, regional, and national stillbirths at 20 weeks' gestation or longer in 204 countries and territories, 1990–2021: findings from the Global Burden of Disease Study 2021

Comfort H., McHugh T. A., Schumacher A. E. et al., The Lancet 2024 Vol. 404 No. 10466 P. 1955–1988

Background Stillbirth is a devastating and often avoidable adverse pregnancy outcome. Monitoring stillbirth levels and trends—in a comprehensive manner that leaves no one uncounted—is imperative for continuing progress in pregnancy loss reduction. This analysis, completed as part of the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021, methodically accounted for different stillbirth definitions ...

Added: November 12, 2024

Global, Regional, and National Burden of Injuries, and Burden Attributable to Injuries Risk Factors, 1990 to 2019: Results from the Global Burden of Disease Study 2019

Malekpour M., Rezaei N., Azadnajafabad S. et al., Public Health 2024 Vol. 237 P. 212–231

Objectives In this study, the trends and current situation of the injury burden as well as attributable burden to injury risk factors at global, regional, and national levels based on the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 are presented. Study design To assess the attributable burden of injury risk factors, the data of ...

Added: October 31, 2024

Global pattern, trend, and cross-country inequality of early musculoskeletal disorders from 1990 to 2019, with projection from 2020 to 2050

Jin Y., Guo C., Abbasian M. et al., Med 2024 Vol. 5 No. 8 P. 943–962.e6

Background This study aims to estimate the burden, trends, forecasts, and disparities of early musculoskeletal (MSK) disorders among individuals ages 15 to 39 years. Methods The global prevalence, years lived with disabilities (YLDs), disability-adjusted life years (DALYs), projection, and inequality were estimated for early MSK diseases, including rheumatoid arthritis (RA), osteoarthritis (OA), low back pain (LBP), neck pain ...

Added: June 11, 2024

Burden of disease scenarios for 204 countries and territories, 2022–2050: a forecasting analysis for the Global Burden of Disease Study 2021

Emil Vollset S., Ababneh H. S., Habtegiorgis Abate Y. et al., The Lancet 2024 Vol. 403 No. 10440 P. 2204–2256

Background Future trends in disease burden and drivers of health are of great interest to policy makers and the public at large. This information can be used for policy and long-term health investment, planning, and prioritisation. We have expanded and improved upon previous forecasts produced as part of the Global Burden of Diseases, Injuries, and Risk ...

Added: May 21, 2024

Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021

Brauer M., Roth G., Aravkin A. et al., The Lancet 2024 Vol. 403 No. 10440 P. 2162–2203

Understanding the health consequences associated with exposure to risk factors is necessary to inform public health policy and practice. To systematically quantify the contributions of risk factor exposures to specific health outcomes, the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 aims to provide comprehensive estimates of exposure levels, relative health risks, ...

Added: May 21, 2024

Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021

Ferrari A., Santomauro D. F., Aali A. et al., The Lancet 2024 Vol. 403 No. 10440 P. 2133–2161

Background Detailed, comprehensive, and timely reporting on population health by underlying causes of disability and premature death is crucial to understanding and responding to complex patterns of disease and injury burden over time and across age groups, sexes, and locations. The availability of disease burden estimates can promote evidence-based interventions that enable public health researchers, policy ...

Added: April 22, 2024