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The exact solution of the mutator model with directed mutations, linear fitness function, and finite genome length
Chinese Journal of Physics. 2018. Vol. 56. No. 5. P. 2235–2240.
Yakushkina T., Saakian D.
In this study, we considered the model by Beckman and Loeb [Proc. Natl. Acad. Sci. U.S.A. 103 (2006) 14140] for the mutator phenomena. We construct an infinite population Crow-Kimura model with a mutator gene, directed mutations, a linear fitness function, and a finite genome length. We solved analytically the dynamics of the model using the generating function method. Such models provide realistic predictions for finite population sizes and have been widely discussed recently. The analytical formulas provided can be used to calculate the advantage of the mutator mechanism for the accumulation of mutations in cancer biology.
Богатырев А. Б., Математический сборник 2023 Т. 214 № 3 С. 106–119
Рассматривается клеточное разбиение пространства модулей вещественных кривых рода 2 с отмеченной точкой на единственном вещественном овале. Клетки перечисляются определенными графами, веса которых описывают комплексную структуру на кривой. Показано, что стягивание ребра графа приводит к корневой особенности естественного отображения из весов графа в пространство модулей кривых. ...
Added: August 14, 2026
Богатырев А. Б., Gendron Q., Успехи математических наук 2023 Т. 78 № 1 С. 209–210
Уравнение Пелля-Абеля — это функциональное уравнение вида P²-DQ² = 1, с заданным многочленом D, свободным от квадратов, и неизвестными многочленами P и Q. Мы показываем, что пространство уравнений Пелля-Абеля с фиксированными степенями D и примитивным решением P является комплексным многообразием. Мы описываем его связные компоненты с помощью эффективно вычислимого инварианта. ...
Added: August 14, 2026
Богатырев А. Б., Transactions of the Moscow Mathematical Society 2024 Vol. 85 No. 2 P. 323–337
The best uniform rational approximation of the Sign function on two intervals separated by zero was explicitly found by E. I. Zolotarëv in 1877. The natural extension of this problem to three bands was solved by E. Stiefel in 1961. We indicate the solutions overlooked by the prominent geometer and study their properties. ...
Added: August 14, 2026
Богатырев А. Б., Успехи математических наук 2026 Т. 81 № 3(489) С. 159–160
Предложена простая и эффективно реализуемая формула для изменения абелевых интегралов (включая их периоды) при вариации образующих классической группы Шоттки, представляющей риманову поврехность. ...
Added: August 14, 2026
Gendron Q., Compositio Mathematica 2025 Vol. 161 No. 7 P. 1483–1511
A Pell–Abel equation is a functional equation of the form P^2-DQ^2=1 , with a given polynomial D free of squares and unknown polynomials P and Q. We show that the space of Pell–Abel equations with the degrees of D and of the primitive solution P fixed is a complex manifold. We describe its connected components ...
Added: August 14, 2026
Yu Z., Wang J., Wang Z. et al., Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences 2026 Vol. 384 P. 1–16
The integration of data-driven and knowledge-driven approaches in generative geospatial modelling (GGM) is often hindered by their mathematical incompatibilities. Here, we propose a geometric algebra (GA)-based framework that employs a unified multi-vector representation to fuse heterogeneous data and diverse knowledge. The framework facilitates structured reasoning and hypothesis generation through a task-adaptable, five-stage cycle: representation, reasoning, ...
Added: August 13, 2026
Cham: Springer, 2026.
This book constitutes the proceedings of the 10th International Workshop Empowering Novel Geometric Algebra for Graphics and Engineering, ENGAGE 2025, held in conjunction with Computer Graphics International conference, CGI 2025, in Hong Kong, China, on July 14, 2025.
The 14 full papers included in this volume were carefully reviewed and selected from 16 submissions. The papers ...
Added: August 13, 2026
Ratnikov F., European Physical Journal: Special Topics 2026 P. 1–10
EEG recordings are often affected by the loss or corruption of individual channels due to electrode detachment, poor scalp contact, or external interference. Such channels must be accurately reconstructed before further analysis. In this study, we investigate Next-Generation Reservoir Computing (NG-RC) as a data-driven approach for reconstructing corrupted EEG channels and compare its performance with ...
Added: August 12, 2026
Speranski S. O., Математические заметки 2026 Т. 120 № 3 С. 470–483
We show that, in terms of closure ordinals, many infinitary calculi for ‘first-order’ logics of probability (i.e., for languages similar to those in [Abadi & Halpern 1994]) are as hard as possible: the corresponding closure ordinals coincide with the least non-constructive ordinal, denoted by $\omega_1^{\mathrm{CK}}$. ...
Added: August 12, 2026
Minets M., Krasnozhenov G., Trofimova E. et al., PeerJ Computer Science 2026 Vol. 12 Article e4063
This article presents CAD2TechSpec, a novel framework for automating design processes within computer-aided design (CAD) systems by leveraging multimodal large language models (LLMs). The framework enables the analysis and generation of detailed design specifications, including the automated creation of machining process plans. Our system architecture combines 3D model rendering, dimensionality reduction techniques, and the capabilities ...
Added: August 12, 2026
Мизинов П. В., Journal of Computer Virology and Hacking Techniques 2023 No. 20 P. 383–396
Biometric vein recognition systems are vulnerable to presentation attacks. Traditionally, researchers have used a near-infrared (NIR) drawing of the user’s vascular bed to create a presentation attack instrument (PAI). This paper investigates the feasibility of using free software to capture a venous pattern of the hand without NIR under normal lighting conditions and to create ...
Added: August 11, 2026
Ali S., Bocharnikov V., Ratnikov F. et al., Sensors 2026 Vol. 26 No. 16 Article 5024
Large distributed sensor arrays require repeated recalibration as radiation damage, material aging, gain variation, and readout drift alter channel responses. We studied a high-granularity calorimeter as a large sensor array and addressed unsupervised recalibration from two unpaired datasets: a nominal reference response and an aged response with attenuated cell-wise signals. Aging was modeled by a ...
Added: August 11, 2026
Trubochkina N. K., М.: Издательство «Юрайт», 2026.
This textbook is designed to develop students' holistic understanding of modern production processes and methods for their analysis and management using machine learning technologies. In the context of the fourth industrial revolution, where traditional engineering disciplines are inextricably intertwined with intelligent data processing methods, there is a growing need for specialists capable of integrating knowledge ...
Added: August 8, 2026
Kulev Y., Maksaev A., Promyslov V., Linear Algebra and its Applications 2026 Vol. 730 P. 51–72
The notion of λ-th upper scrambling index was introduced by Huang and Liu in 2010, as a generalization of a notion considered by Akelbek and Kirkland in 2009. For a primitive digraph D, it is defined as the smallest positive integer k such that for every λ vertices of D there exist directed paths of lengths k from these vertices to a common vertex. This ...
Added: August 7, 2026
Kanunnikov A., Promyslov V., Vassilieva E., Electronic Journal of Combinatorics 2024 Vol. 31 No. 3 Article P3.6
Introduced by Goulden and Jackson in their 1996 paper, the matchings-Jack conjecture and the hypermap-Jack conjecture (also known as the b-conjecture) are two major open questions relating Jack symmetric functions, the representation theory of the symmetric groups and combinatorial maps. They show that the coefficients in the power sum expansion of some Cauchy sum for ...
Added: August 7, 2026
Фирсанова В. И., ACM, 2026.
The inclusion of autistic people can be augmented by a mobile app that provides information without a human mediator making information perception more liberating for people in the spectrum. This paper is an overview of a doctoral work dedicated to the development of a web-based mobile tool for supporting the inclusion of people on the ...
Added: August 4, 2026
Фирсанова В. И., Хлусова Я. К., CEUR Workshop Proceedings, 2025.
Knowledge graphs are widely used in Retrieval Augmented Generation (RAG) and Explainable AI (XAI), since they can illustrate semantic relationships generated by Large Language Models (LLMs). Recent studies focus on generating knowledge graphs from unstructured data to improve RAG performance; however, they do not explain the underlying graph structure. The analysis of synthetic graphs behind ...
Added: August 4, 2026
Spiridonov V. P., Belousov N. M., Sarkissian G. A., Analysis and Mathematical Physics 2026 Vol. 16 Article 96
Hyperbolic hypergeometric integrals are defined as Barnes-type integrals of products of hyperbolic gamma functions. Their reduction to ordinary hypergeometric functions is well known. We study in detail their degeneration to complex hypergeometric functions. Namely, using uniform bounds on the integrands, we prove that the univariate hyperbolic beta integral and the conical function degenerate to two-dimensional ...
Added: August 4, 2026
Gayfullin S., Kikteva V., Results in Mathematics 2026 Vol. 81 No. 5 Article 146
In this paper we obtain a criterion of flexibility for an affine complexity-zero horospherical variety. This result generalizes previously known results on flexibility of normal horospherical varieties, horospherical varieties with an action of a semisimple group, and non-normal toric varieties. ...
Added: August 3, 2026
Anfisa V. Popova, Bykova D., Fedonin G. et al., Molecular Biology and Evolution 2025 Vol. 42 No. 11 Article msaf264
Many Mycobacterium tuberculosis (MTB) genome sites experience different selective forces depending on whether a patient is treated with antibiotics. Here, we searched for pairs of such sites that evolve interdependently. We reconstructed the phylogeny of more than 11,000 MTB clinical isolates with known phenotypes for at least one of 13 antitubercular drugs. By analyzing the ...
Added: November 18, 2025
Popova A., Neverov A. D., Nature Communications 2020 Vol. 11 Article 4603
Amino acid propensities at a site change in the course of protein evolution. This may happen for two reasons. Changes may be triggered by substitutions at epistatically interacting sites elsewhere in the genome. Alternatively, they may arise due to environmental changes that are external to the genome. Here, we design a framework for distinguishing between ...
Added: June 9, 2025
Popova A., Neverov A. D., Proceedings of the National Academy of Sciences of the United States of America 2019 Vol. 116 No. 42 P. 21104–21112
Influenza A virus (IAV) is a major public health problem and a pandemic threat. Its evolution is largely driven by diversifying positive selection so that relative fitness of different amino acid variants changes with time due to changes in herd immunity or genomic context, and novel amino acid variants attain fitness advantage. Here, we hypothesize ...
Added: June 9, 2025
Klink G. V., Kalinina O. V., Bazykin G. A., PLoS Computational Biology 2022 Vol. 18 No. 2 Article e1009878
Fitness conferred by the same allele may differ between genotypes and environments, and these differences shape variation and evolution. Changes in amino acid propensities at protein sites over the course of evolution have been inferred from sequence alignments statistically, but the existing methods are data-intensive and aggregate multiple sites. Here, we develop an approach to ...
Added: June 26, 2024
Klink G. V., Kalinina O., Bazykin G., Virus Evolution 2024 Vol. 10 No. 1 Article veae036
Amino acid preferences at a protein site depend on the role of this site in protein function and structure as well as on external constraints. All these factors can change in the course of evolution, making amino acid propensities of a site time-dependent. When viral subtypes divergently evolve in different host subpopulations, such changes may ...
Added: June 26, 2024