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Приложение к журналу Вопросы онкологии. Тезисы X Петербургского международного онкологического форума "Белые ночи 2024"
СПб. :
АННМО «Вопросы онкологии», 2024.
Dzhalilova D., Zolotova N., Fokichev N. et al., PeerJ 2023 Vol. 11 Article e16159
Background
Colorectal cancer (CRC) is the third most common cancer. It is a heterogeneous disease, including both hereditary and sporadic types of tumors. CRC results from complex interactions between various genetic and environmental factors. Inflammatory bowel disease is an important risk factor for developing CRC. Despite growing understanding of the CRC biology, preclinical models are still ...
Added: March 26, 2025
Русских С. В., Москвичева Л. И., Tarasenko E. A. et al., Здоровье населения и среда обитания 2023 Т. 31 № 7 С. 15–25
Introduction: Job satisfaction of oncologists at outpatient cancer centers is an important factor that determines not only personal well-being of a doctor, but also the effectiveness of provision, quality and availability of primary specialized oncological care. Objectives: To assess the risk of emotional burnout and to determine the level of job satisfaction of oncologists working ...
Added: August 18, 2023
Tran K. B., Lang J. J., Compton K. et al., The Lancet 2022 Vol. 400 No. 10352 P. 563–591
Background
Understanding the magnitude of cancer burden attributable to potentially modifiable risk factors is crucial for development of effective prevention and mitigation strategies. We analysed results from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 to inform cancer control planning efforts globally.
Methods
The GBD 2019 comparative risk assessment framework was used to estimate ...
Added: August 23, 2022
Kocarnik J., Compton K., Dean F. et al., JAMA Oncology 2022 Vol. 8 No. 3 P. 420–444
Importance: The Global Burden of Diseases, Injuries, and Risk Factors Study 2019 (GBD 2019) provided systematic estimates of incidence, morbidity, and mortality to inform local and international efforts toward reducing cancer burden.
Objective: To estimate cancer burden and trends globally for 204 countries and territories and by Sociodemographic Index (SDI) quintiles from 2010 to ...
Added: January 1, 2022
Rozenberg J., Zvereva S., Dalina A. et al., Cells 2021 Vol. 10 No. 12 Article 3516
Understanding the mechanisms that regulate cancer progression is pivotal for the development of new therapies. Although p53 is mutated in half of human cancers, its family member p73 is not. At the same time, isoforms of p73 are often overexpressed in cancers and p73 can overtake many p53 functions to kill abnormal cells. According to ...
Added: December 23, 2021
GBD 2019 Adolescent Young Adult Cancer C., Otstavnov S., Vlassov V., The Lancet Oncology 2022 Vol. 23 No. 1 P. 27–52
Background: In estimating the global burden of cancer, adolescents and young adults with cancer are often overlooked, despite being a distinct subgroup with unique epidemiology, clinical care needs, and societal impact. Comprehensive estimates of the global cancer burden in adolescents and young adults (aged 15-39 years) are lacking. To address this gap, we analysed ...
Added: December 13, 2021
Espiritu D., Gribkova A., Gupta S. et al., Journal of Physical Chemistry B 2021 Vol. 125 No. 16 P. 3963–3976
At the cellular level, cancer is the disease of both the
genome and the epigenome, and the interplay between genetic
mutations and epigenetic states may occur at the level of
elementary chromatin units, the nucleosomes. They are formed
by a segment of DNA wrapped around an octamer of histone
proteins. In this review, we survey various mechanisms of cancer
etiology and ...
Added: September 14, 2021
Бердышева Е. С., Topos (Философско-культурологический журнал) 2020 № 1 С. 86–110
This article discusses the cultural, institutional and political foundations of the price of a key line of drug treatment for HER2+ breast cancer in Russia. The social biography of trustuzumab, targeted innovative drug for the treatment of metastatic breast cancer with tumor overexpression of HER2, is used as an empirical example – widely famous and ...
Added: October 2, 2020
Духанина Л. Н., Maksimenko A., Вопросы онкологии 2020 Т. 66 № 4 С. 315–324
The article analyzes the topics of the Russian-language segment of social media related to state support for countering and preventing cancer. Based on a quantitative and qualitative analysis of unstructured oncodiscourse data with a retrospective from 2016 to 2019, followed by highlighting the most resonant events that were reflected in social Russian-language media, the main ...
Added: August 31, 2020
Vlassov V., JAMA Oncology 2019 P. 1749–1768
Importance Cancer and other noncommunicable diseases (NCDs) are now widely recognized as a threat to global development. The latest United Nations high-level meeting on NCDs reaffirmed this observation and also highlighted the slow progress in meeting the 2011 Political Declaration on the Prevention and Control of Noncommunicable Diseases and the third Sustainable Development Goal. Lack of ...
Added: October 21, 2019
Pyatnitskiy M., Карпов Д., Мошковский С., Биомедицинская химия 2018 Т. 64 № 4 С. 303–314
Понятие критически важных генов, чья утрата функции приводит к гибели клетки, является одной
из основополагающих концепций генетики и имеет важное значение для фундаментальных и прикладных
исследований. Особенно перспективно изучение данной области применительно к онкологии, поскольку поиск
генетических уязвимостей раковых клеток позволяет выявить новые потенциальные мишени для противоопухолевой терапии. Современные возможности биотехнологий позволяют проводить крупномасштабные проекты по секвенированию соматических ...
Added: October 29, 2018
Ella Y Tyuryumina, Alexey A Neznanov, Plos One 2018 Vol. 13 No. 7 P. 1–16
The goal of this research is to improve the accuracy of predicting the breast cancer (BC) pro- cess using the original mathematical model referred to as CoMPaS. The CoMPaS is the original mathematical model and the corresponding software built by modelling the natural history of the primary tumor (PT) and secondary distant metastases (MTS), it ...
Added: July 7, 2018
Vlassov V., JAMA Oncology 2018 Vol. 4 No. 11 P. 1553–1568
Importance:
The increasing burden due to cancer and other noncommunicable diseases poses a threat to human development, which has resulted in global political commitments reflected in the Sustainable Development Goals as well as the World Health Organization (WHO) Global Action Plan on Non-Communicable Diseases. To determine if these commitments have resulted in improved cancer control, quantitative ...
Added: June 5, 2018
Vlassov V., JAMA Oncology 2017 Vol. 3 No. 12 P. 1683–1691
Question What is the burden of liver cancer globally, what are the major risk factors for liver cancer across countries, regions, and at the global level and how did these change between 1990 and 2015?
Findings There were 854 000 incident liver cancer cases and 810 000 deaths globally in 2015, contributing to 20 578 000 disability-adjusted life-years. Hepatitis B ...
Added: October 8, 2017
Бердышева Е. С., Гольдман О. Э., Вестник общественного мнения. Данные. Анализ. Дискуссии 2017 Т. 1-2 № 124 С. 152–160
В статье описываются результаты целевого массового опроса москвичей, имеющих онкологический диагноз, проведенного в рамках реализации общественного контроля реализации майских указов Президента РФ, направленных на улучшение статистики злокачественных новообразований в России. В центре исследования находятся отдельные аспекты функционирования онкологической помощи в России, а именно – степень онконастороженности россиян и их готовность к самостоятельному профилактическому онкомониторингу; информированность ...
Added: August 24, 2017
Vlassov V., JAMA Oncology 2017 Vol. 3 No. 4 P. 524–548
Importance:
Cancer is the second leading cause of death worldwide. Current estimates on the burden of cancer are needed for cancer control planning.
Objective:
To estimate mortality, incidence, years lived with disability (YLDs), years of life lost (YLLs), and disability-adjusted life-years (DALYs) for 32 cancers in 195 countries and territories from 1990 to 2015.
Evidence Review:
Cancer mortality was estimated ...
Added: December 25, 2016
Vlassov V., JAMA Oncology 2015 Vol. 1 No. 4 P. 505–527
ABSTRACT
Cancer is among the leading causes of death worldwide. Current estimates of cancer burden in individual countries and regions are necessary to inform local cancer control strategies.
OBJECTIVE
To estimate mortality, incidence, years lived with disability (YLDs), years of life lost (YLLs), and disability-adjusted life-years (DALYs) for 28 cancers in 188 countries by sex from 1990 to ...
Added: June 7, 2015