The real work is devoted to the solution of problems of interaction of the subjects of innovative activity (SIA) in the Russian Federation. Problems of interaction of SID pour out, as a rule, in problems of a mutual dissatisfaction between the parties with the participating in creation of innovations and their consumers. The mutual dissatisfaction with participants of innovative activity is expressed in statements of such character when representatives of innovative ideas and projects complain about representatives of business that business isn't interested in new and advanced technological developments and products of innovative activity. In return business shows discontent with quality and level of innovative developments of scientific community by representatives. Unfortunately, such situation proceeds over fifteen years and each of the parties is sincerely sure of the correctness. In the present book the author has made an attempt to understand the reasons of problems of development of innovative process in Russia. As an example of regional innovative system the Nizhny Novgorod Region where the author of the present monograph conducted surveys and interview of tens of innovative companies and other participants of innovative activity in 2014 has been chosen. The book consists of three heads, in each of which is devoted to the following questions: In chapter 1 of work research of forms known for today and scientific methods of interaction between subjects of innovative activity is conducted. In chapter 2 field and desk researches of factors of development of interaction of subjects of innovative activity are described. In a chapter 3 the mechanisms allowing to develop forms and methods of interaction of SID in Russia are offered.