International Symposium on Functional Neuroimaging: Basic Research and Clinical Applications. Abstracts
The “International Symposium on Functional Neuroimageing: Basic Research and Clinical Applications” took place at the Moscow State University of Psychology and Education on May 22nd-24th, 2012. The aim of the symposium was to contribute to implementation of neuroimaging methods in Russia and to familiarize Russian researchers, students and everyone interested with the modern methods of visualization of human brain processes. Russian research groups are only starting such researches and that is why the symposium was a prominent event for the Russian science.
The problem of non-invasive preoperative localization of motor areas in human cortex has not been solved yet. In clinical practice, localization of the hand representation in the primary motor cortex often becomes one of the main goals of the pre-surgical evaluation. In healthy subjects the area of the motor hand representation usually corresponds to certain standard anatomical landmarks (hand knob in the precentral gyrus), which can be easily found in sMRI images. Unfortunately, in patients with various brain lesions these landmarks may be absent or not corresponding to the area of the motor cortex. In such cases, location of irreplacable areas must be determined according to their functional and/or temporal dynamical characteristics.
It might become a promising method of localizing primary motor area by way of taking into account the characteristic properties of the primary motor cortex temporal dynamics during movement preparation.
Key characteristics of non-fluent (Broca, motor) aphasia are, among others, verb finding difficulties and effortful speech output. These characteristics are related to different levels of speech production (lexical retrieval and motor execution). This study was aimed at identifying normative brain activation related to verb production in healthy individuals, as well as patterns of its reorganization depending on the locus of the linguistic deficit in patients with non-fluent aphasia.